Results 141 to 150 of about 334,749 (357)
Advanced Materials, EarlyView.This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Linzixuan Zhang +17 more
wiley +1 more source
mBioSeveral bacterial vaginosis (BV)-associated bacteria have been associated with elevated risk of human immunodeficiency virus (HIV) acquisition; however, susceptibility of these bacteria to antibiotics is poorly understood.
D. J. Valint +4 more
doaj +1 more source
Genomic data analysis in tree spaces [PDF]
arXiv, 2016 Recently, an elegant approach in phylogenetics was introduced by Billera-Holmes-Vogtmann that allows a systematic comparison of different evolutionary histories using the metric geometry of tree spaces. In many problem settings one encounters heavily populated phylogenetic trees, where the large number of leaves encumbers visualization and analysis in ...
arxiv
Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications
Advanced Materials Technologies, EarlyView.This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin +8 more
wiley +1 more source
Defining a Simulation Strategy for Cancer Immunocompetence [PDF]
arXiv, 2013 Although there are various types of cancer treatments, none of these currently take into account the effect of ageing of the immune system and hence altered responses to cancer. Recent studies have shown that in vitro stimulation of T cells can help in the treatment of patients.
arxiv
Case of Inoperable Cancer of the Fauces, the Pharynx, the Tongue, and the Cervical Glands that has shown Marked Amelioration after Treatment for Ten Weeks with a Bacterial Vaccine of Neoformans [PDF]
, 1906 Scanes Spicer, A. E. Wright
openalex +1 more source
Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors
Advanced Therapeutics, EarlyView.Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe +4 more
wiley +1 more source
VaccinesSARS-CoV-2 vaccination-induced protection against infection is likely to be affected by functional antibody features. To understand the kinetics of antibody responses in healthy individuals after primary series and third vaccine doses, sera from the ...
Jimmie L. Bullock +9 more
doaj +1 more source
Determining Positive Cancer Rescue Mutations in p53 Based Cancers by using Artificial Intelligence [PDF]
arXiv, 2017 A mutation in a protein-coding gene in DNA can alter the protein structure coded by the same gene. Structurally altered proteins usually lose their functions and sometimes gain an undesirable function instead. These types of mutations and their effects can result in genetic diseases or antibiotic resistant bacteria, among other health issues. Important
arxiv