Results 151 to 160 of about 339,306 (357)
Co-delivery of human cancer-testis antigens with adjuvant in protein nanoparticles induces higher cell-mediated immune responses. [PDF]
, 2018 Nanoparticles have attracted considerable interest as cancer vaccine delivery vehicles for inducing sufficient CD8+ T cell-mediated immune responses to overcome the low immunogenicity of the tumor microenvironment.
Kim, Tae Il +5 more
core +2 more sources
Micro‐ and Nano‐Bots for Infection Control
Advanced Materials, EarlyView.This review presents a strategic vision for integrating micro‐ and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on ...
Azin Rashidy Ahmady +5 more
wiley +1 more source
VaccinesSARS-CoV-2 vaccination-induced protection against infection is likely to be affected by functional antibody features. To understand the kinetics of antibody responses in healthy individuals after primary series and third vaccine doses, sera from the ...
Jimmie L. Bullock +9 more
doaj +1 more source
Advanced Materials, EarlyView.This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Linzixuan Zhang +17 more
wiley +1 more source
Preventive and therapeutic vaccines for human papillomavirus-associated cervical cancers [PDF]
, 2000 Morris Ling +3 more
openalex +2 more sources
Viral gene drive spread during herpes simplex virus 1 infection in mice
Nature CommunicationsGene drives are genetic modifications designed to propagate efficiently through a population. Most applications rely on homologous recombination during sexual reproduction in diploid organisms such as insects, but we recently developed a gene drive in ...
Marius Walter +13 more
doaj +1 more source
A vaccine containing autogenous term placenta and an immunopoteniator to reduce the incidence of autochthonous cancer [PDF]
, 1978 C K Vitou, Barid B. Mukherjee
openalex +1 more source
Advanced Materials, EarlyView.Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash +9 more
wiley +1 more source
Gene editing for latent herpes simplex virus infection reduces viral load and shedding in vivo
Nature CommunicationsAnti-HSV therapies are only suppressive because they do not eliminate latent HSV present in ganglionic neurons, the source of recurrent disease. We have developed a potentially curative approach against HSV infection, based on gene editing using HSV ...
Martine Aubert +10 more
doaj +1 more source