Results 171 to 180 of about 184,119 (211)
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Current Gene Therapy, 2007
Cytotoxic chemotherapy is associated with modest survival advantage as initial treatment of advanced lung cancer. However, toxicity and minimal benefit to use second line treatment justifies exploration of alternative approaches. Recent understanding of mechanisms by which tumor antigen recognition can be enhanced has justified development of a recent ...
Rob, Eager +2 more
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Cytotoxic chemotherapy is associated with modest survival advantage as initial treatment of advanced lung cancer. However, toxicity and minimal benefit to use second line treatment justifies exploration of alternative approaches. Recent understanding of mechanisms by which tumor antigen recognition can be enhanced has justified development of a recent ...
Rob, Eager +2 more
openaire +2 more sources
2012 Sixth International Conference on Complex, Intelligent, and Software Intensive Systems, 2012
Cancer vaccine research is a hot topic for medical treatments of cancer. Identification of candidate antigenic stimuli for the vaccine is already improved using immune-informatics. Subsequent test in vivo are expensive and time consuming. There is an increasing request to a modeling approach to speed up this phase of vaccine research.
PAPPALARDO, FRANCESCO, MOTTA, Santo
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Cancer vaccine research is a hot topic for medical treatments of cancer. Identification of candidate antigenic stimuli for the vaccine is already improved using immune-informatics. Subsequent test in vivo are expensive and time consuming. There is an increasing request to a modeling approach to speed up this phase of vaccine research.
PAPPALARDO, FRANCESCO, MOTTA, Santo
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Expert Opinion on Therapeutic Targets, 2004
Cancer vaccines - a dream or a reality? There is no doubt that a time will come when this new approach to cancer treatment will provide opportunities that will be both complementary and synergistic with existing treatments. Novelty is often linked to risk, and if there is a given medical field that desperately needs therapeutic improvement, cancer is ...
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Cancer vaccines - a dream or a reality? There is no doubt that a time will come when this new approach to cancer treatment will provide opportunities that will be both complementary and synergistic with existing treatments. Novelty is often linked to risk, and if there is a given medical field that desperately needs therapeutic improvement, cancer is ...
openaire +2 more sources
Surgical Oncology Clinics of North America, 2007
Therapeutic cancer vaccines target the cellular arm of the immune system to initiate a cytotoxic T-lymphocyte response against tumor-associated antigens. Immunotherapy offers one of the few therapeutic options that reproducibly leads to a subset of patients with long-term remissions (seemingly cures) of widely metastatic disease.
Lilah F, Morris, Antoni, Ribas
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Therapeutic cancer vaccines target the cellular arm of the immune system to initiate a cytotoxic T-lymphocyte response against tumor-associated antigens. Immunotherapy offers one of the few therapeutic options that reproducibly leads to a subset of patients with long-term remissions (seemingly cures) of widely metastatic disease.
Lilah F, Morris, Antoni, Ribas
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Current Opinion in Immunology, 2002
Increasingly, data from distinct experimental systems show that immunity can be activated to prevent tumors. The rationale for prevention is strong because, in that setting, one deals with an immune system that is neither impaired by tumor- and treatment-induced suppression nor tolerant to tumor-associated antigens that have been encountered in the ...
Olivera J, Finn, Guido, Forni
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Increasingly, data from distinct experimental systems show that immunity can be activated to prevent tumors. The rationale for prevention is strong because, in that setting, one deals with an immune system that is neither impaired by tumor- and treatment-induced suppression nor tolerant to tumor-associated antigens that have been encountered in the ...
Olivera J, Finn, Guido, Forni
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Expert Opinion on Biological Therapy, 2010
Personalized medicine has extended to management of cancer and implies prescription of specific therapeutics best suited for an individual patient and the type of tumor. These principles have been applied to cancer vaccines.Various cancer vaccines that can be personalized. Tumor-derived vaccines have been used and active immunotherapy based on antigens
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Personalized medicine has extended to management of cancer and implies prescription of specific therapeutics best suited for an individual patient and the type of tumor. These principles have been applied to cancer vaccines.Various cancer vaccines that can be personalized. Tumor-derived vaccines have been used and active immunotherapy based on antigens
openaire +2 more sources
Expert Opinion on Therapeutic Patents, 2001
The intellectual property literature concerning novel cancer vaccine strategies for the period of 1998 and 2000 is reviewed. Nearly 400 citations have been identified and the majority of the citations described herein involve the identification of new tumour associated antigens and novel strategies of cancer vaccine formulations. Significant progresses
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The intellectual property literature concerning novel cancer vaccine strategies for the period of 1998 and 2000 is reviewed. Nearly 400 citations have been identified and the majority of the citations described herein involve the identification of new tumour associated antigens and novel strategies of cancer vaccine formulations. Significant progresses
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Current Opinion in Immunology, 2006
The immunological bases of current approaches to therapeutic cancer vaccination (or 'vacci-treatment') have been established for a decade or longer. The new developments lie mostly in the lessons learnt from clinical testing of these approaches. Three lessons are particularly worthy of note.
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The immunological bases of current approaches to therapeutic cancer vaccination (or 'vacci-treatment') have been established for a decade or longer. The new developments lie mostly in the lessons learnt from clinical testing of these approaches. Three lessons are particularly worthy of note.
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Advanced Drug Delivery Reviews, 2019
Immunotherapy is revolutionizing the treatment of cancer, and the current immunotherapeutics have remarkably improved the outcomes for some cancer patients. However, we still need answers for patients with immunologically cold tumors that do not benefit from the current immunotherapy treatments.
Yoosoo, Yang +4 more
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Immunotherapy is revolutionizing the treatment of cancer, and the current immunotherapeutics have remarkably improved the outcomes for some cancer patients. However, we still need answers for patients with immunologically cold tumors that do not benefit from the current immunotherapy treatments.
Yoosoo, Yang +4 more
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Expert Opinion on Investigational Drugs, 1998
A new era involving the evaluation of recombinant cancer vaccines has begun with the concurrent emergence of insights and technologies in the fields of molecular biology and immunology. These advances include: The identification and cloning of an array of genes associated with the neoplastic process, such as oncogenes, suppressor genes, genes encoding ...
J, Schlom +6 more
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A new era involving the evaluation of recombinant cancer vaccines has begun with the concurrent emergence of insights and technologies in the fields of molecular biology and immunology. These advances include: The identification and cloning of an array of genes associated with the neoplastic process, such as oncogenes, suppressor genes, genes encoding ...
J, Schlom +6 more
openaire +2 more sources