Results 121 to 130 of about 286,222 (357)

Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]

, 2013
Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E., Denniss, Frances, Guinn, Barbara-Ann, Khan, Ghazala, Sigurdardottir, Dagmar   +4 more
core   +3 more sources

Unfolding and Degradation of Micellar Immunodrug Carriers Derived From End Group Modified Aliphatic Poly(Carbonate)s with Acid‐Responsive Ketal Side Groups

Advanced Materials, EarlyView.
An acid‐responsive polymeric micelle system based of aliphatic poly(carbonate)s with benzyl ketal side chains is designed for targeted immunodrug delivery. It can disassemble in endosomal environments, enabling site‐specific immunoactivation and enhanced biodegradability.
Adrian V. Hauck, Michael Fichter, Laura J. Rosenberger, Jannis Willig, Alexander Fuchs, Felicia Schön, Paul Schneider, Carolina Medina‐Montano, Taufiq Ahmad, Jessica Erlenbusch, Pol Besenius, Leonard Kaps, Matthias Bros, Stephan Grabbe, Volker Mailänder, Jürgen Groll, Lutz Nuhn   +16 more
wiley   +1 more source

Current status of clinical research on breast cancer vaccines

结直肠肛门外科
Breast cancer vaccines mainly activate the patient’s own immune system to fight against breast cancer. With the continuous development of immunology, research on breast cancer vaccines has made significant progress, but they are still in the clinical ...
Chu Zhiliang, Yao Yubo, Wang Xiaoming, Li Shuhua, Ge Xueyan   +4 more
doaj   +1 more source

Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis [PDF]

, 2019
Background More than 10 years have elapsed since human papillomavirus (HPV) vaccination was implemented. We did a systematic review and meta-analysis of the population-level impact of vaccinating girls and women against human ...
\uc9lodie, B\ue9nard, A Kahn, Jessica, A Machalek, Dorothy, A Smith, Megan, Ali, Hammad, Baldo, Vincenzo, Boily, MarcMarie\uadClaude, Brassard, Paul, Brisson,, Callander, Denton, Checchi, Marta, Cocchio, Silvia, Dalianis, Tina, Dehlendorff, Christian, Donovan, Basil, F Chow, Eric P, G Pollock, Kevin, Gr\ufcn, Nathalie, Harrison, Christopher, Herweijer, Eva, J Woestenberg, Petra, Jes\ufas Purri\uf1os\uadHermida, Mar\ueda, K Fairley, Christopher, K Kjaer, Susanne, Kavanagh, Kimberley, L Brotherton, Julia M, L Deeks, Shelley, Liu, Bette, M Garland, Suzanne, M Imburgia, Teresa, M Johnson, Anne, M Wheeler, Cosette, M\ue9lanie, Drolet, Markowitz, Lauri, Mesher, David, Munk, Christian, Niccolai, Linda, Norma, P\ue9rez, Nyg\ue5rd, Mari, Ogilvie, Gina, Oliphant, Jeannie, S\uf6derlund\uadStrand, Anna, Sonnenberg, Pam, Sparen, P\ue4r, Steben, Marc, T Hansen, Bo, Tanton, Clare, V Kliewer, Erich, W Flagg, Elaine, W Gargano, Julia, Yu., Bo Nancy   +50 more
core   +2 more sources

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Human Papillomavirus: How Social Ideologies Influence Medical Policy and Care [PDF]

, 2012
The purpose of this paper is to discuss the ways in which new advances in the production of a vaccine against human papillomavirus (HPV) have been received by both the general public and the medical community.
Hachem, Fadi
core   +1 more source

Immunogenicity of targeted lentivectors [PDF]

, 2014
To increase the safety and possibly efficacy of HIV-1 derived lentivectors (LVs) as an anti-cancer vaccine, we recently developed the Nanobody (Nb) display technology to target LVs to antigen presenting cells (APCs).
Adotévi, Bennett, Bevan, Bhardwaj, Bhardwaj, Bhardwaj, Blander, Bonehill, Bonehill, Breckpot, Breckpot, Breckpot, Charleston, Chuah, Collins, Collins, Collins, Collins, Cosset, Diebold, Donckier, Eggermont, Enk, Figdor, Gajewski, Garcia, Groettrup, Inaba, Kast, Lahoutte, Lévy, McCullough, Medzhitov, Melief, Mellman, Mortha, Moser, Moser, Munn, Naldini, Neyns, Noguiez-Hellin, Nussenzweig, Palena, Raes, Reis e Sousa, Reiser, Reiser, Richardson, Romani, Roncarolo, Sakuma, Schroyens, Semesyuk, Song, Storm, Thielemans, Thielemans, Thielemans, Thielemans, Torretta, Turk, Van Kooyk, Wang, Wang, Yamaguchi, Yewdell, Yu   +67 more
core   +3 more sources

Cancer vaccines [PDF]

QJM, 1996
L G, Durrant, I, Spendlove
openaire   +2 more sources

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

HIV-1 suppression and rare dolutegravir resistance in antiretroviral-experienced people with HIV in Liberia

Communications Medicine
Background Increasingly, persons with HIV in Liberia are receiving antiretroviral therapy containing the integrase strand-transfer inhibitor (InSTI) dolutegravir (DTG), but the prevalence of and factors associated with virologic failure and HIV drug ...
James Soka Moses, Alice K. Pau, Safia Kuriakose, Greg Grandits, Cavan Reilly, Brad T. Sherman, Weizhong Chang, Lisheng Dai, Muhammad A. Khan, Helene Highbarger, Moses Mannah, Johnathan McCullough, Carla Chorley, Isaac Morlu, Joseph Dorbor, Ophelia Talweh Bongolee, Rebecca Slewion, Esther Akpa, Barthalomew Wilson, April L. Poole, Stacy L. Kopka, Tracey Miller, Cecelia J. Nuta, Christina Lindan, David Glidden, Jeffrey N. Martin, Kumblytee L. Johnson, Robin L. Dewar, Ian Wachekwa, Stephen A. Migueles   +29 more
doaj   +1 more source