Results 261 to 270 of about 286,222 (357)

Emerging Therapeutic Strategies for Lung Cancer: The Role of Immunotherapy and HPV-Targeted Cancer Vaccines. [PDF]

Vaccines (Basel)
Bhaliya K, Anwer M, Wei MQ.
europepmc   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, EarlyView.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +2 more sources

Harnessing immunotherapy: cancer vaccines as novel therapeutic strategies for brain tumor. [PDF]

Front Immunol
Kiel K, Piranlioglu R, Godlewski J, Bronisz A.   +3 more
europepmc   +1 more source

Lipopolyplex-formulated mRNA cancer vaccine elicits strong neoantigen-specific T cell responses and antitumor activity [PDF]

Ting Fan, Congcong Xu, Jichuan Wu, Yihua Cai, WuQiang Cao, Haifa Shen, Mingna Zhang, Hanfei Zhu, Jingxian Yang, Zhounan Zhu, Xiaopin Ma, Jiale Ren, Lei Huang, Qianyun Li, Yuying Tang, Bo Yu, Chunxiu Chen, Mingcheng Xu, Qiuhe Wang, Zhuya Xu, Fengjia Chen, Shujing Liang, Zhixian Zhong, Anmbreen Jamroze, Dean G. Tang, Hangwen Li, Chunyan Dong   +26 more
openalex   +1 more source

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng, Juping Sun, Junyu Liu, Yuqi Zhang, Wanwan Liu, Xiaobin Li, Han Wu, Juan Li, Jisong Zhang, Chanyuan Jin, Can Yang Zhang   +10 more
wiley   +1 more source

Shared epitopes create safety and efficacy concerns in several cancer vaccines. [PDF]

J Immunother Cancer
Kellermann G, Mograbi B, Hofman P, Brest P.   +3 more
europepmc   +1 more source

A phase-1/2 study of adenovirus-p53 transduced dendritic cell vaccine in combination with indoximod in metastatic solid tumors and invasive breast cancer

, 2018
Hatem Soliman, Fatema Khambati, Hyo S. Han, Roohi Ismail‐Khan, Marilyn M. Bui, Daniel M. Sullivan, Scott Antonia   +6 more
openalex   +2 more sources

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source