Results 71 to 80 of about 163,730 (308)

Chiral Microneedle Arrays With Terahertz Chiroptical Activity With Chiral‐Plasmon‐Chiral‐Phonon Resonance

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Microneedle arrays (MNAs) is a rapidly emerging technology with broad biomedical applications in drug delivery and biosensing. With sub‐millimeter dimensions and periodicity, MNAs possess geometries nearly ideal for biomedical devices operating within the terahertz (THz) spectral window.
Sang Hyun Lee   +6 more
wiley   +1 more source

Hitchhiking on Controlled-Release Drug Delivery Systems: Opportunities and Challenges for Cancer Vaccines

open access: yesFrontiers in Pharmacology, 2021
Cancer vaccines represent among the most promising strategies in the battle against cancers. However, the clinical efficacy of current cancer vaccines is largely limited by the lack of optimized delivery systems to generate strong and persistent ...
Lu Han   +6 more
doaj   +1 more source

Trypsin digest of cancer cells surface stimulates anti-tumor immune response better than cancer cells themselves

open access: yes, 2010
Antigens expressed on the surface of cancer cells are accessible targets for both humoral and cell-mediated immune responses, and are therefore potential candidates for vaccine development.
Balashova Elena, Petr Lokhov
core   +2 more sources

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

open access: yesAdvanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi   +9 more
wiley   +1 more source

Biomaterial-enhanced cancer vaccines

open access: yesMaterials & Design, 2022
Cancer vaccines are a promising strategy for preventing cancer progression through antitumor immunity activation. Some vaccines, such as Sipuleucel-T (an autologous active cellular immunotherapy), have been applied clinically.
Shengxian Li   +4 more
doaj   +1 more source

Vaccines Against Non-Infectious, Non-Cancer Novel Targets

open access: yes, 2015
This chapter discusses vaccines against non-infectious, non-cancer novel targets. It is part of a collection which takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines
Dimitrios Lamprou   +15 more
core   +1 more source

Developing Effective Cancer Vaccines Using Rendered-Inactive Tumor Cells

open access: yes, 2023
Cancer is a major public health threat, and researchers are constantly looking for new ways to develop effective treatments. One approach is the use of cancer vaccines, which work by boosting the body’s immune system to fight cancer.
Bin Wang   +4 more
core   +1 more source

Microneedles Mediated Delivery of Nanodiamonds for Quantum Sensing of Free Radicals in Skin Tissue

open access: yesAdvanced Materials Technologies, EarlyView.
Fluorescent nanodiamonds are nanoscale sensors capable of monitoring cellular stress responses. However, to function effectively, they must be delivered into cells or tissues. Here, we demonstrate their application in the skin by developing a dissolvable microneedle platform that dissolves after skin insertion, enabling the delivery of nanodiamonds ...
Siyu Fan   +10 more
wiley   +1 more source

Tissue vaccines for cancer

open access: yesExpert Review of Vaccines, 2007
Most tumors, including prostate carcinoma, are heterogeneous mixtures of neoplastic cells and supporting stromal matrix. Attempts to vaccinate as a means to treat or prevent cancer have typically relied on use of a single antigen or cell type. In the case of whole-cell vaccines, clonal populations of cancer cells are grown in culture and harvested for ...
Mark A, Suckow   +2 more
openaire   +2 more sources

Areas of Uncertainty in SARS-CoV-2 Vaccination for Cancer Patients

open access: yes, 2022
Early in the COVID-19 pandemic, it was recognized that infection with SARS-CoV-2 is associated with increased morbidity and mortality in patients with cancer; therefore, preventive vaccination in cancer survivors is expected to be particularly impactful.
Anastasios Dimou, Dimou, Anastasios
core   +1 more source

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