Results 71 to 80 of about 5,770,101 (353)

Cancer vaccines: past, present and future; a review article

Discover Oncology, 2022
Immunotherapy and vaccines have revolutionized disease treatment and prevention. Vaccines against infectious diseases have been in use for several decades. In contrast, only few cancer vaccines have been approved for human use. These include preventative
Eddie Grimmett, Bayan Al-Share, Mohamad Basem Alkassab, Ryan Weng Zhou, Advait Desai, Mir Munir A. Rahim, Indryas Woldie   +6 more
doaj   +1 more source

Therapeutic cancer vaccines [PDF]

Journal of Clinical Investigation, 2015
The clinical benefit of therapeutic cancer vaccines has been established. Whereas regression of lesions was shown for premalignant lesions caused by HPV, clinical benefit in cancer patients was mostly noted as prolonged survival. Suboptimal vaccine design and an immunosuppressive cancer microenvironment are the root causes of the lack of cancer ...
Melief, C.J.M., Hall, T. van, Arens, R., Ossendorp, F., Burg, S.H. van der   +4 more
openaire   +3 more sources

IL-7: A promising adjuvant ensuring effective T cell responses and memory in combination with cancer vaccines?

Frontiers in Immunology, 2022
Cancer vaccines exhibit specificity, effectiveness, and safety as an alternative immunotherapeutic strategy to struggle against malignant diseases, especially with the rapid development of mRNA cancer vaccines in recent years.
Yue Zhao, Kongyuan Wei, Hao Chi, Zhijia Xia, Xiaosong Li   +4 more
semanticscholar   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Expression of HIV from a 1-LTR circular DNA in the absence of integration

Retrovirology
Background Like all retroviruses, two kinds of viral DNA are present in the nucleus of HIV-infected cells: integrated DNA and a pool of unintegrated DNA containing linear and circular forms. For the most part, it has been difficult to examine the role of
Corrado Gurgo, Claudio Fenizia, Katherine McKinnon, Ru-ching Hsia, Genoveffa Franchini   +4 more
doaj   +1 more source

mRNA vaccine in cancer therapy: Current advance and future outlook

Clinical and Translational Medicine, 2023
Messenger ribonucleic acid (mRNA) vaccines are a relatively new class of vaccines that have shown great promise in the immunotherapy of a wide variety of infectious diseases and cancer.
Youhuai Li, Mina Wang, Xueqiang Peng, Yingying Yang, Qishuang Chen, Jiaxing Liu, Qing She, Jichao Tan, Chuyuan Lou, Zehuan Liao, Xuexin Li   +10 more
doaj   +1 more source

Characterization of Murine Breast Cancer Cell Lines for Anti-Cancer Vaccine [PDF]

, 2017
Breast cancer is the most commonly diagnosed cancer in women and the second leading cause of cancer death among women in the United States (1). While treatments involving radiation and chemotherapy currently exist, disease must be detected early in order
Frazier, Haven N
core   +2 more sources

Using Intervention Mapping to Develop an Efficacious Multicomponent Systems-Based Intervention to Increase Human Papillomavirus (HPV) Vaccination in a Large Urban Pediatric Clinic Network [PDF]

, 2020
Background: The CDC recommends HPV vaccine for all adolescents to prevent cervical, anal, oropharyngeal, vaginal, vulvar, and penile cancers, and genital warts. HPV vaccine rates currently fall short of national vaccination goals.
Coan, Sharon P., Crawford, Claire A., Frost, Erica L., Gabay, Efrat K., Healy, C. Mary, Savas, Lara S., Shegog, Ross, Spinner, Stanley W., Vernon, Sally W.   +8 more
core   +2 more sources

Lung Cancer Vaccines [PDF]

The Cancer Journal, 2011
To date, in lung cancer, early attempts to modulate the immune system via vaccine-based therapeutics have been unsuccessful. An improved understanding of tumor immunology has facilitated the production of more sophisticated lung cancer vaccines. It is anticipated that it will likely require multiple epitopes of a diverse set of genes restricted to ...
Ronan J, Kelly, Giuseppe, Giaccone
openaire   +2 more sources

Beyond Just Peptide Antigens: The Complex World of Peptide-Based Cancer Vaccines

Frontiers in Immunology, 2021
Peptide-based cancer vaccines rely upon the strong activation of the adaptive immune response to elicit its effector function. They have shown to be highly specific and safe, but have yet to prove themselves as an efficacious treatment for cancer in the ...
Alexander J. Stephens, N. Burgess-Brown, Shisong Jiang   +2 more
semanticscholar   +1 more source