TREM2 Recognition of Candidalysin Orchestrates Mucosal Immunity in Oropharyngeal Candidiasis
Abstract The landscape of oral mucosal immunity, particularly in the context of oropharyngeal candidiasis (OPC), remains largely uncharted. By employing single-cell RNA sequencing (scRNA-seq) on murine models of OPC, we have illuminated the immune dynamics within this niche.
Weiwei Deng +12 more
openaire +1 more source
Characterisation of the p38 signalling pathway in candidalysin-induced epithelial activation [PDF]
, 2022 Nikou, Spyridoula
core
Characterisation of EGFR signalling events induced by Candida albicans and the cytolytic peptide toxin, candidalysin [PDF]
, 2021 Ponde, Nicole
core
Screen for Candida albicans Virulence Factors that Modulate the Host Immune Response in the Larval Zebrafish [PDF]
Candida is one of the most frequent causes of bloodstream infections in the U.S. The first line of defense against these invasive infections is the innate immune system.
Blair, Bailey A
core +1 more source
Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin [PDF]
, 2022 Nicole O. Ponde +9 more
openalex +1 more source
Quantification of biophysical properties of candidalysin, a fungal peptide toxin secreted by C. albicans during invasion [PDF]
, 2023 Gaukhar Zhurgenbayeva +1 more
openalex +1 more source
Effects of Candidalysin Derived from Candida albicans on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts [PDF]
Candida albicans (Ca) is frequently detected in the peri-implant sulcus with peri-implantitis, a major postoperative complication after oral implant therapy. However, the involvement of Ca in the pathogenesis of peri-implantitis remains unclear.
Hiroshima, Yuka +8 more
core
Candida albicans epithelial invasion induces host membrane rupture at distinct subcellular niches following priming by the fungal toxin candidalysin [PDF]
Noa Conan +6 more
openalex +1 more source
Identification of Candidalysin: a Candida albicans peptide toxin involved in epithelial damage [PDF]
, 2016 Sarah Höfs
openalex