Results 131 to 140 of about 1,624 (196)

Candida auris-Macrophage Cellular Interactions and Transcriptional Response [PDF]

, 2023
The pathogenic yeast Candida auris represents a global threat of the utmost clinical relevance. This emerging fungal species is remarkable in its resistance to commonly used antifungal agents and its persistence in the nosocomial settings.
Lorenz, Michael C, Miramón, Pedro, Pountain, Andrew W   +2 more
core   +1 more source

The role of the C. albicans transcriptional repressor NRG1 during filamentation and disseminated candidiasis is strain dependent

mSphere
Candida albicans is one of the most common causes of superficial and invasive fungal diseases in humans. Its ability to cause disease is closely linked to its ability to undergo a morphological transition from budding yeast to filamentous forms (hyphae ...
Rohan S. Wakade, Melanie Wellington, Damian J. Krysan   +2 more
doaj   +1 more source

Author response: The Candida albicans virulence factor candidalysin polymerizes in solution to form membrane pores and damage epithelial cells

, 2022
C. Russell, Katherine G. Schaefer, Andrew C. Dixson, Amber L. H. Gray, Robert J. Pyron, Daiane S. Alves, Nicholas Moore, Elizabeth A. Conley, Ryan J Schuck, Tommi White, D. Thanh, Gavin M. King, Francisco N. Barrera   +12 more
openalex   +1 more source

Recent advances in understanding Candida albicans hyphal growth [PDF]

International audienceMorphological changes are critical for the virulence of a range of plant and human fungal pathogens. is a major human fungal Candida albicans pathogen whose ability to switch between different morphological states is associated with
Arkowitz, Robert, Bassilana, Martine
core   +1 more source

918 Candidalysin, a virulence factor of Candida albicans, activates human keratinocytes through MAPK and NF-κB pathways [PDF]

, 2018
Pu Song, François Niyonsaba, Kazuhiro Okumura, Shigaku Ikeda, H. Ogawa   +4 more
openalex   +1 more source

Screen for Candida albicans Virulence Factors that Modulate the Host Immune Response in the Larval Zebrafish [PDF]

Candida is one of the most frequent causes of bloodstream infections in the U.S. The first line of defense against these invasive infections is the innate immune system.
Blair, Bailey A
core   +1 more source

Challenging the first line of defense: Candida albicans interactions with epithelial barriers during infection and translocation [PDF]

Candida albicans is commonly found as a member of the healthy human microbiome on mucosal surfaces. Despite mostly existing as a harmless commensal, C. albicans is also an opportunistic pathogen.
Sprague, Jakob
core   +1 more source

Transcriptomic insights into Candida albicans adaptation to an anaerobic environment

Microbiology Spectrum
Candida albicans is a clinically significant fungal pathogen capable of adapting to diverse host environments, including steep oxygen gradients ranging from ~21% oxygen to anaerobic.
Karen D. Zeise, John R. Erb-Downward, Gary B. Huffnagle   +2 more
doaj   +1 more source

Effects of Candidalysin Derived from Candida albicans on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts [PDF]

Candida albicans (Ca) is frequently detected in the peri-implant sulcus with peri-implantitis, a major postoperative complication after oral implant therapy. However, the involvement of Ca in the pathogenesis of peri-implantitis remains unclear.
Hiroshima, Yuka, Ichikawa, Tetsuo, Kawano, Hiromichi, Kido, Jun-ichi, Murakami, Akikazu, Naruishi, Koji, Nishikawa, Yasufumi, Tomotake, Yoritoki, Yumoto, Hiromichi   +8 more
core  

Molecular approach to early diagnosis of colonizing or invasive Candida in critically ill ventilated patients [PDF]

, 2019
Candida colonization is a frequent event in respiratory tract of non-immunocompromised intensive care unit (ICU) ventilated patients. From 5 to 30% ofCandidacolonization patients will develop Invasive Candidiasis (IC), which is usually a late-onset ICU ...
PHAN, Thang
core