Results 141 to 147 of about 1,118 (147)
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Polymers of the candidalysin peptide become membrane pores
Biophysical Journal, 2023Charles M. Russell +9 more
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International Immunopharmacology
Oropharyngeal candidiasis significantly impacts patients' quality of life. Although the immune mechanisms underlying OPC have been explored, the roles of immune checkpoints and macrophages in this context remain unclear. We employed single-cell techniques to analyze changes in the oral immune microenvironment and explored the role of Tim-3 in OPC.
Siqi, Liu +9 more
openaire +2 more sources
Oropharyngeal candidiasis significantly impacts patients' quality of life. Although the immune mechanisms underlying OPC have been explored, the roles of immune checkpoints and macrophages in this context remain unclear. We employed single-cell techniques to analyze changes in the oral immune microenvironment and explored the role of Tim-3 in OPC.
Siqi, Liu +9 more
openaire +2 more sources
When platelets meet candidalysin: “We just Wnt to have fun”
Allergy, 2022Ozlem Bulut +2 more
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Candidalysin meets the kynurenine pathway: a tale of damage and regulation
Candida albicans is a commensal fungus that colonises the gastrointestinal tract and transitions from yeast to hyphal morphology during invasion. The hyphal form secretes candidalysin, which is a cytolytic peptide essential for disrupting epithelial barriers, invading tissue, and activating pro-inflammatory immune responses. The kynurenine pathway (KP)openaire +1 more source
Insights into the evolution of Candidalysin and recent developments
Archives of MicrobiologyAnanya Konwar +5 more
openaire +1 more source
Candidalysin pre-pore assembly in solution is under kinetic control
Biophysical JournalCharles M. Russell +4 more
openaire +1 more source