Investigating the transcriptome of Candida albicans in a dual-species Staphylococcus aureus biofilm model [PDF]
, 2021 Candida albicans is an opportunistic pathogen found throughout multiple body sites and is frequently co-isolated from infections of the respiratory tract and oral cavity with Staphylococcus aureus. Herein we present the first report of the effects that S.
Brown, Jason L +9 more
core +1 more source
Fangchinoline inhibits growth and biofilm of Candida albicans by inducing ROS overproduction
Journal of Cellular and Molecular Medicine, Volume 28, Issue 9, May 2024.Abstract Infections caused by Candida species, especially Candida albicans, threaten the public health and create economic burden. Shortage of antifungals and emergence of drug resistance call for new antifungal therapies while natural products were attractive sources for developing new drugs.
Longfei Yang +4 more
wiley +1 more source
New insights into immunity to skin fungi shape our understanding of health and disease [PDF]
, 2022 Fungi represent an integral part of the skin microbiota. Their complex interaction network with the host shapes protective immunity during homeostasis. If host defences are breached, skin-resident fungi including Malassezia and Candida, and environmental
LeibundGut‐Landmann, Salomé +1 more
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“Nutrient–fungi–host” tripartite interaction in cancer progression
iMeta, Volume 3, Issue 2, April 2024.Interactions between nutrient and fungi in cancer development and treatment remain under investigation. In this article, we aim to provide insights into the relationships between fungi and various categories of cancer, mediated by diverse nutrient sensing pathways of fungi in response to external environment.
Di Wu +6 more
wiley +1 more source
MECHANISTIC INSIGHTS INTO THE ROLES OF IL-22/IL-22RA1 AXIS IN ORAL ANTIFUNGAL IMMUNITY [PDF]
, 2020 Oropharyngeal candidiasis (OPC, oral thrush) is an opportunistic infection caused by the commensal fungus Candida albicans. IL-17 and IL-22 are produced by Type 17 lymphocytes.Both cytokines mediate antifungal immunity yet activate quite distinct ...
Aggor, FEY
core
Diverse mechanisms control amino acid‐dependent environmental alkalization by Candida albicans
Molecular Microbiology, Volume 121, Issue 4, Page 696-716, April 2024.Glutamate dehydrogenase (Gdh2), a central enzyme of nitrogen metabolism, is dispensable for the virulent growth of Candida spp., including C. albicans, C. glabrata, and C. auris. Gdh2 deaminates mitochondria‐derived glutamate generating ammonia, alkalinizing the extracellular environment.
Fitz Gerald S. Silao +4 more
wiley +1 more source
Molecular Microbiology, Volume 121, Issue 4, Page 727-741, April 2024.The regulatory factor X (RFX) gene family comprises a diverse group of transcriptional regulators with a unique winged‐helix DNA binding domain. In contrast to model yeasts that harbor a single RFX gene, the genome of the pathogenic yeast C. albicans encodes two RFX homologs.
Diana L. Rodríguez +2 more
wiley +1 more source
Cover Image: Candidalysin delivery to the invasion pocket is critical for host epithelial damage induced by Candida albicans (Cellular Microbiology 10/2021) [PDF]
, 2021 Selene Mogavero +13 more
openalex +1 more source
Towards improved quantitative live-cell imaging [PDF]
Confocal microscopy is well known for its capability to produce 3D images with increased optical resolution and contrast in living multicellular thick samples.
Dasgupta, Anindita
core +1 more source
Candida auris-Macrophage Cellular Interactions and Transcriptional Response [PDF]
, 2023 The pathogenic yeast Candida auris represents a global threat of the utmost clinical relevance. This emerging fungal species is remarkable in its resistance to commonly used antifungal agents and its persistence in the nosocomial settings.
Lorenz, Michael C +2 more
core +1 more source