Results 81 to 90 of about 1,118 (147)

Cross‐Sectional and Prospective Association of Serum 25‐Hydroxyvitamin D with Gut Mycobiota during Pregnancy among Women with Gestational Diabetes

open access: yesMolecular Nutrition &Food Research, Volume 68, Issue 11, June 2024.
There is limited research conducted on the relationship between vitamin D and gut mycobiota. This study reveals that individuals with sufficient serum vitamin D exhibit a decreased abundance of fecal Saccharomyces. The results obtain from the vitamin D genetic risk score analysessupport this relationship.
Yuhui Liang   +14 more
wiley   +1 more source

Candida albicans Morphology-Dependent Host FGF-2 Response as a Potential Therapeutic Target

open access: yesJournal of Fungi, 2019
Angiogenesis mediated by proteins such as Fibroblast Growth Factor-2 (FGF-2) is a vital component of normal physiological processes and has also been implicated in contributing to the disease state associated with various microbial infections.
Sandeep Vellanki   +3 more
doaj   +1 more source

Digestive dynamics: Unveiling interplay between the gut microbiota and the liver in macronutrient metabolism and hepatic metabolic health

open access: yesPhysiological Reports, Volume 12, Issue 12, June 2024.
Abstract Although the liver is the largest metabolic organ in the body, it is not alone in functionality and is assisted by “an organ inside an organ,” the gut microbiota. This review attempts to shed light on the partnership between the liver and the gut microbiota in the metabolism of macronutrients (i.e., proteins, carbohydrates, and lipids).
Mrunmayee R. Kandalgaonkar   +2 more
wiley   +1 more source

Fangchinoline inhibits growth and biofilm of Candida albicans by inducing ROS overproduction

open access: yesJournal of Cellular and Molecular Medicine, Volume 28, Issue 9, May 2024.
Abstract Infections caused by Candida species, especially Candida albicans, threaten the public health and create economic burden. Shortage of antifungals and emergence of drug resistance call for new antifungal therapies while natural products were attractive sources for developing new drugs.
Longfei Yang   +4 more
wiley   +1 more source

“Nutrient–fungi–host” tripartite interaction in cancer progression

open access: yesiMeta, Volume 3, Issue 2, April 2024.
Interactions between nutrient and fungi in cancer development and treatment remain under investigation. In this article, we aim to provide insights into the relationships between fungi and various categories of cancer, mediated by diverse nutrient sensing pathways of fungi in response to external environment.
Di Wu   +6 more
wiley   +1 more source

Diverse mechanisms control amino acid‐dependent environmental alkalization by Candida albicans

open access: yesMolecular Microbiology, Volume 121, Issue 4, Page 696-716, April 2024.
Glutamate dehydrogenase (Gdh2), a central enzyme of nitrogen metabolism, is dispensable for the virulent growth of Candida spp., including C. albicans, C. glabrata, and C. auris. Gdh2 deaminates mitochondria‐derived glutamate generating ammonia, alkalinizing the extracellular environment.
Fitz Gerald S. Silao   +4 more
wiley   +1 more source

Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκB-mediated barrier protection.

open access: yesPLoS Pathogens
The opportunistic fungal pathogen Candida albicans thrives on human mucosal surfaces as a harmless commensal, but frequently causes infections under certain predisposing conditions.
Jakob L Sprague   +13 more
doaj   +1 more source

EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin [PDF]

open access: gold, 2022
Nicole O. Ponde   +9 more
openalex   +1 more source

The Candida albicans virulence factor candidalysin polymerizes in solution to form membrane pores and damage epithelial cells

open access: gold, 2022
C. Russell   +12 more
openalex   +1 more source

Effects of Candidalysin Derived from Candida albicans on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts [PDF]

open access: gold, 2023
Yasufumi Nishikawa   +8 more
openalex   +1 more source

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