Results 81 to 90 of about 1,624 (196)

IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis [PDF]

, 2016
Signaling through the IL-17 receptor (IL-17R) is required to prevent oropharyngeal candidiasis (OPC) in mice and humans. However, the IL-17-responsive cell type(s) that mediate protection are unknown.
Brane, Lucas, Bruno, Vincent M., Childs, Erin E., Coleman, Bianca M., Conti, Heather R., Cruz, J. Agustin, Daugherty, Sean, Filler, Scott G., Gaffen, Sarah L., Garg, Abhishek V., Hendricks, Matthew R., Hise, Amy G., Hunter, Joseph P., Kolls, Jay K., Mengesha, Bemnet G., Naglik, Julian R., Richardson, Jonathan P., Saevig, Danielle L., Sinha, Satrajit, Solis, Norma, Verma, Akash H.   +20 more
core   +1 more source

New Insights in Candida albicans Innate Immunity at the Mucosa: Toxins, Epithelium, Metabolism, and Beyond

Frontiers in Cellular and Infection Microbiology, 2020
The mucosal surfaces of the human body are challenged by millions of microbes on a daily basis. Co-evolution with these microbes has led to the development of plastic mechanisms in both host and microorganisms that regulate the balance between preserving
Aize Pellon, Shervin Dokht Sadeghi Nasab, David L. Moyes   +2 more
doaj   +1 more source

Cell biology of Candida albicans-host interactions [PDF]

, 2016
Acknowledgements The authors are supported by the Wellcome Trust via a Senior Investigator Award to NG, an ISST award and a Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology.
Da Silva Dantas, Alessandra, Gow, Neil Andrew Robert, LEE, Kathy K, Raziunaite, Ingrida, Schaefer, Katja, Wagener, Jeanette, Yadav, Bhawna   +6 more
core   +1 more source

The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition of Candida albicans [PDF]

, 2023
Purpose of Review The fungus Candida albicans has evolved to live in close association with warm-blooded hosts and is found frequently on mucosal surfaces of healthy humans. As an opportunistic pathogen, C.
Jacobsen, Ilse D.
core   +1 more source

Ahr1-dependent regulation of ECE1 and other core filamentation response genes in Candida albicans [PDF]

, 2020
Candida albicans is a normally harmless commensal fungus and part of the human microbiota. However, in immunocompromised patients, C. albicans can cause diseases ranging from superficial infections to life threatening systemic infections.
Ruben, Sophia
core   +1 more source

Candida albicans and oral carcinogenesis. A brief review. [PDF]

, 2021
Current medical knowledge and research on patients’ management are still evolving, and several protocols on minimizing risk of infection by Candidaspp.among the population have developed.
Andrea Ballini, Angela Pia Cazzolla, Francesco Inchingolo, Ioannis Alexandros Charitos, Luigi Santacroce, Michele Di Cosola   +5 more
core   +1 more source

CARD9⁺ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment [PDF]

, 2019
This work was supported by the Intramural Research Program of the National Institute of Allergy and Infectious Disease, National Institutes of Health, as well as NIH grants awarded to TMH (R01 093808), SGF (R01AI124566) and SRL (R01CA161373).
A. Lira, Sergio, Bohrer, Andrea C., C. Schaefer, Brian, D. Brown, Gordon, D. Mayer-Barber, Katrin, Dambuza, Ivy M., Drummond, Rebecca A., G. Filler, Scott, Hube, Bernhard, Iwakura, Yoichir, M. Hohl, Tobias, Naglik, Julian Richard, Oikonomou, Vasileios, S. Lionakis, Michail, Swamydas, Muthulekha, Zhai, Bing   +15 more
core   +3 more sources

The cell biology of the Trichosporon-Host interaction [PDF]

, 2017
Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are ...
Akoumianaki, Alby, Aratani, Arendrup, Arikawa, Arts, Bentubo, Cheng, Childers, Chitasombat, Choi, Colombo, Cong, Crawford, da Silva Dantas, de Almeida Junior, de Almeida Junior, Di Bonaventura, Ene, Ene, Erwig, Fernandes, Figueiredo-Carvalho, Fonseca, Fontaine, Gacser, Garlanda, Gish, Gouba, Gravelat, Gresnigt, Higashino-Kameda, Hole, Iliev, Karashima, Kontoyiannis, Kronstad, Krysan, Lamas, Lanternier, Lee, Li, Lyman, Lyman, Marine, Moalli, Monari, Moyes, Moylett, Muranaka, Nosanchuk, Pande, Picard, Piccioni, Quintin, Reddy, Richardson, Rieber, Rodriguez-Tudela, Rohatgi, Saeed, Sandai, Sasaki, Saunders, Schwartz, Sokol, Sriswasdi, Sugita, Sugita, Sun, Suzuki, Taylor-Smith, Thywißen, Walsh, Walsh, Wynne, Yauch, Zaragoza, Zelante, Zhang, Zhang, Zhang   +81 more
core   +1 more source

Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin [PDF]

Science Immunology, 2017
Candidalysin, a hypha-associated fungal peptide, drives interleukin-17 responses to Candida albicans .
Akash Verma, Jonathan P. Richardson, Chunsheng Zhou, Bianca M. Coleman, David L. Moyes, Jemima Ho, Anna R. Huppler, Kritika Ramani, Mandy J. McGeachy, Ilgiz A. Mufazalov, Ari Waisman, Larry Kane, Partha S. Biswas, Bernhard Hube, Julian R. Naglik, Sarah L. Gaffen   +15 more
openalex   +7 more sources

Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers

mBio, 2018
Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, these ...
Stefanie Allert, Toni M. Förster, Carl-Magnus Svensson, Jonathan P. Richardson, Tony Pawlik, Betty Hebecker, Sven Rudolphi, Marc Juraschitz, Martin Schaller, Mariana Blagojevic, Joachim Morschhäuser, Marc Thilo Figge, Ilse D. Jacobsen, Julian R. Naglik, Lydia Kasper, Selene Mogavero, Bernhard Hube   +16 more
doaj   +1 more source