Results 91 to 100 of about 1,628 (159)

Cortactin: A major cellular target of viral, protozoal, and fungal pathogens

Molecular Microbiology, Volume 122, Issue 2, Page 165-183, August 2024.
Recent advances in research on various viral, protozoal, and fungal pathogens have deepened our understanding of microbial virulence strategies and human disease development. Cortactin, a key host protein involved in actin cytoskeletal dynamics, has emerged as crucial player in host–microbe interactions, with pathogens manipulating its expression and ...
Irshad Sharafutdinov, Barbara Friedrich, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer   +4 more
wiley   +1 more source

Candida albicans Morphology-Dependent Host FGF-2 Response as a Potential Therapeutic Target

Journal of Fungi, 2019
Angiogenesis mediated by proteins such as Fibroblast Growth Factor-2 (FGF-2) is a vital component of normal physiological processes and has also been implicated in contributing to the disease state associated with various microbial infections.
Sandeep Vellanki, Eun Young Huh, Stephen P. Saville, Soo Chan Lee   +3 more
doaj   +1 more source

Cross‐Sectional and Prospective Association of Serum 25‐Hydroxyvitamin D with Gut Mycobiota during Pregnancy among Women with Gestational Diabetes

Molecular Nutrition &Food Research, Volume 68, Issue 11, June 2024.
There is limited research conducted on the relationship between vitamin D and gut mycobiota. This study reveals that individuals with sufficient serum vitamin D exhibit a decreased abundance of fecal Saccharomyces. The results obtain from the vitamin D genetic risk score analysessupport this relationship.
Yuhui Liang, Zengliang Jiang, Yuanqing Fu, Sha Lu, Zelei Miao, Menglei Shuai, Xinxiu Liang, Wanglong Gou, Ke Zhang, Rui‐Qi Shi, Chang Gao, Mei‐Qi Shi, Xu‐Hong Wang, Wen‐Sheng Hu, Ju‐Sheng Zheng   +14 more
wiley   +1 more source

Characterization and evaluation of the antifungal activity of antibodies raised against Candida Albicans germ tube in a rabbit model of infection and patients with invasive Candidiasis. [PDF]

, 2018
236 p.In the last decades, the incidence of Invasive Candidiasis has dramatically increased. Since Candida is a common component of human microbiota, the distinction between invasion and colonization is complicated.
Carrano, Giulia
core   +4 more sources

Hemolytic Activity of Vaginal Candida albicans Isolates and Antifungal Effects of Quinalizarin with Hemolysis Modulation

Pathogens
This study evaluated the hemolytic activity of Candida albicans isolates from the female reproductive tract and investigated the in vitro effects of quinalizarin on fungal growth, hemolysis, and ECE1 expression. Ninety-four clinical C.
Monika Janeczko, Elżbieta Kochanowicz
doaj   +1 more source

Effects of Candidalysin Derived from Candida albicans on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts [PDF]

, 2023
Candida albicans (Ca) is frequently detected in the peri-implant sulcus with peri-implantitis, a major postoperative complication after oral implant therapy. However, the involvement of Ca in the pathogenesis of peri-implantitis remains unclear.
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core  

Digestive dynamics: Unveiling interplay between the gut microbiota and the liver in macronutrient metabolism and hepatic metabolic health

Physiological Reports, Volume 12, Issue 12, June 2024.
Abstract Although the liver is the largest metabolic organ in the body, it is not alone in functionality and is assisted by “an organ inside an organ,” the gut microbiota. This review attempts to shed light on the partnership between the liver and the gut microbiota in the metabolism of macronutrients (i.e., proteins, carbohydrates, and lipids).
Mrunmayee R. Kandalgaonkar, Virender Kumar, Matam Vijay‐Kumar   +2 more
wiley   +1 more source

Fangchinoline inhibits growth and biofilm of Candida albicans by inducing ROS overproduction

Journal of Cellular and Molecular Medicine, Volume 28, Issue 9, May 2024.
Abstract Infections caused by Candida species, especially Candida albicans, threaten the public health and create economic burden. Shortage of antifungals and emergence of drug resistance call for new antifungal therapies while natural products were attractive sources for developing new drugs.
Longfei Yang, Xiaonan Wang, Zhiming Ma, Yujie Sui, Xin Liu   +4 more
wiley   +1 more source

Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκB-mediated barrier protection.

PLoS Pathogens
The opportunistic fungal pathogen Candida albicans thrives on human mucosal surfaces as a harmless commensal, but frequently causes infections under certain predisposing conditions.
Jakob L Sprague, Tim B Schille, Stefanie Allert, Verena Trümper, Adrian Lier, Peter Großmann, Emily L Priest, Antzela Tsavou, Gianni Panagiotou, Julian R Naglik, Duncan Wilson, Sascha Schäuble, Lydia Kasper, Bernhard Hube   +13 more
doaj   +1 more source

Membrane Activity of the Fungal Peptide Toxin Candidalysin [PDF]

Biophysical Journal, 2018
Christian Nehls, Julia Wernecke, Laura Paulowski, Mareike Lewke, Helena S. Fabritz, Julian R. Naglik, Bernhard Hube, Thomas Gutsmann   +7 more
openaire   +1 more source