Results 81 to 90 of about 1,079 (138)

The role of the C. albicans transcriptional repressor NRG1 during filamentation and disseminated candidiasis is strain dependent

mSphere
Candida albicans is one of the most common causes of superficial and invasive fungal diseases in humans. Its ability to cause disease is closely linked to its ability to undergo a morphological transition from budding yeast to filamentous forms (hyphae ...
Rohan S. Wakade, Melanie Wellington, Damian J. Krysan   +2 more
doaj   +1 more source

TREM2 Recognition of Candidalysin Orchestrates Mucosal Immunity in Oropharyngeal Candidiasis

Abstract The landscape of oral mucosal immunity, particularly in the context of oropharyngeal candidiasis (OPC), remains largely uncharted. By employing single-cell RNA sequencing (scRNA-seq) on murine models of OPC, we have illuminated the immune dynamics within this niche.
Weiwei Deng, Yishan Chen, Siqi Liu, Kefan Lin, Kai Zhang, Di Wang, Zhiying Yu, Weijia Zhao, Yingping Xu, Xiaowen Wang, Bin Yang, Ruoyu Li, Yunsheng Liang   +12 more
openaire   +1 more source

An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans

Nature Communications
Candida albicans is a ubiquitous fungus in the human gut yet there is little understanding as to how crosstalk between the fungus and the host regulates gut colonization.
Pallavi Kakade, Juan F. Burgueno, Shabnam Sircaik, Nicole O. Ponde, Jinke Li, Iuliana V. Ene, Jiwoong Kim, Shen-Huan Liang, Rebecca Yunker, Ipsita Dey, Yasutada Akiba, Shipra Vaishnava, Jonathan D. Kaunitz, Sing Sing Way, Andrew Y. Koh, Sarah L. Gaffen, Maria T. Abreu, Richard J. Bennett   +17 more
doaj   +1 more source

Candidalysin promotes fungal-specific Th17 CD4 T cell differentiation and protective systemic immunogenicity. [PDF]

Mucosal Immunol
Nguyen NNM, Brady AE, Haslam DB, Frazer C, Pham G, Bennett RJ, Way SS.   +6 more
europepmc   +1 more source

Hidden battles: dissecting host-fungal interactions and immune heterogeneity in infection outcomes. [PDF]

mSphere
Drummond RA.
europepmc   +1 more source

The pathogenicity and future treatment strategies of <i>Candida albicans</i>. [PDF]

Front Cell Infect Microbiol
Wu J, Jiang C, Wang H, Chen T, Chen X, Da W.   +5 more
europepmc   +1 more source

The role and possible mechanism of intestinal fungi in the progression of chronic liver diseases. [PDF]

NPJ Biofilms Microbiomes
Hu Y, Yang Y, Wang S, Chu H.
europepmc   +1 more source

Fungal infection drives metabolic reprogramming in epithelial cells via aerobic glycolysis and an alternative TCA cycle shunt. [PDF]

Sci Adv
Pellon A, Sadeghi Nasab SD, Bidkhori G, Griffiths JS, Vaga S, Begum N, Blagojevic M, Sigh NK, Kotowicz NK, Uzochukwu I, Le Guennec A, Henley-Smith R, Gregson-Williams H, Clasen F, Pryce M, Karimpour N, Cook R, Anguita J, Richardson JP, Thavaraj S, Naglik JR, Shoaie S, Moyes DL.   +22 more
europepmc   +1 more source

Critical parameters of fungal pathogenicity at the epithelial interphase. [PDF]

Microlife
Möslinger A, Allert S, Vylkova S, Hube B.   +3 more
europepmc   +1 more source

Induction of IκBζ augments cytokine production by candidalysin in oral epithelial cells

Journal of Osaka Dental University, 2023
DOMAE, Eisuke, YOSHIKAWA, Yoshihiro, KAMADA, Aiko, IKEO, Takashi   +3 more
openaire   +1 more source