Results 61 to 70 of about 1,628 (159)

Zinc Limitation Induces a Hyper-Adherent Goliath Phenotype in Candida albicans [PDF]

, 2017
Pathogenic microorganisms often face acute micronutrient limitation during infection due to the action of host-mediated nutritional immunity. The human fungal pathogen Candida albicans is polymorphic and its morphological plasticity is one of its most ...
Alasio, Ameglio, Amich, Andreini, Andreini, Anzaldi, Ballou, Bedell, Bensen, Bottone, Boyce, Butler, Cassat, Citiulo, Crawford, Dade, Do, Ene, Enjalbert, Finkel, Gil-Bona, Gow, Gow, Heilmann, Hickman, Hood, Jacobsen, Jung, Kane, Kehl-Fie, Kehl-Fie, Klis, Kullberg, Liu, Loboda, Lu, MacCallum, Maresca, Martin, Massey, McManus, Mech, Mora-Montes, Moreno, Moyes, Nobile, Noble, Okagaki, Okagaki, Pande, Polke, Schneider, Sentandreu, Skaar, Soloviev, Sudbery, Sudbery, Tyc, Urban, Wachtler, Wachtler, Wagener, Waldron, Walsham, Whiteway, Wilson, Wilson, Wilson, Yano, Zaragoza, Zipfel   +70 more
core   +2 more sources

Dynamic expression of candidalysin facilitates oral colonization of Candida albicans in mice. [PDF]

Nat Microbiol
Abstract Candida albicans is a common fungal member of the human microbiota but can also cause infections via expression of virulence factors associated with the yeast-to-hyphae transition. The evolutionary selection pressure to retain these pathogenic traits for a commensal microorganism remains unclear.
Fróis-Martins R, Lagler J, Schille TB, Elshafee O, Martinez de San Vicente K, Mertens S, Stokmaier M, Kilb I, Sertour N, Bachellier-Bassi S, Mogavero S, Sanglard D, d'Enfert C, Hube B, LeibundGut-Landmann S.   +14 more
europepmc   +3 more sources

New Insights in Candida albicans Innate Immunity at the Mucosa: Toxins, Epithelium, Metabolism, and Beyond

Frontiers in Cellular and Infection Microbiology, 2020
The mucosal surfaces of the human body are challenged by millions of microbes on a daily basis. Co-evolution with these microbes has led to the development of plastic mechanisms in both host and microorganisms that regulate the balance between preserving
Aize Pellon, Shervin Dokht Sadeghi Nasab, David L. Moyes   +2 more
doaj   +1 more source

A variant ECE1 allele contributes to reduced pathogenicity of Candida albicans during vulvovaginal candidiasis.

PLoS Pathogens, 2021
Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide.
Junyan Liu, Hubertine M E Willems, Emily A Sansevere, Stefanie Allert, Katherine S Barker, David J Lowes, Andrew C Dixson, Zhenbo Xu, Jian Miao, Christian DeJarnette, Helene Tournu, Glen E Palmer, Jonathan P Richardson, Francisco N Barrera, Bernhard Hube, Julian R Naglik, Brian M Peters   +16 more
doaj   +1 more source

Candida albicans-Induced Epithelial Damage Mediates Translocation through Intestinal Barriers

mBio, 2018
Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, these ...
Stefanie Allert, Toni M. Förster, Carl-Magnus Svensson, Jonathan P. Richardson, Tony Pawlik, Betty Hebecker, Sven Rudolphi, Marc Juraschitz, Martin Schaller, Mariana Blagojevic, Joachim Morschhäuser, Marc Thilo Figge, Ilse D. Jacobsen, Julian R. Naglik, Lydia Kasper, Selene Mogavero, Bernhard Hube   +16 more
doaj   +1 more source

Oral Microbiota: Findings, Classification, Clinical Significance, and Therapeutic Interventions for Human Systemic Diseases

iMetaMed, Volume 2, Issue 1, March 2026.
Oral microbiota: findings, classification, clinical significance, and therapeutic interventions for human systemic diseases ABSTRACT The oral microbiota is an ecological community of commensal, symbiotic, and pathogenic microorganisms that colonizes the oral cavity.
Miao Zhang, Meihang Du, Wenjiang Zhang, Renhuan Huang, Wanting Li, Tongqi Li, Junping Bai, Ning Zhang, Jungang Chen, Jing Zhou, Bing Wang, Liwei An, Hideaki Kagami, Yiming Zhang   +13 more
wiley   +1 more source

It Takes Two to Tango: How a Dysregulation of the Innate Immunity, Coupled With Candida Virulence, Triggers VVC Onset

Frontiers in Microbiology, 2021
Vulvovaginal candidiasis (VVC) is a symptomatic inflammation of the vagina mainly caused by C. albicans. Other species, such as C. parapsilosis, C. glabrata, C. tropicalis, and C. krusei, are mainly associated to the recurrent form of the disease (RVVC),
Andrea Ardizzoni, Robert T. Wheeler, Robert T. Wheeler, Eva Pericolini, Eva Pericolini   +4 more
doaj   +1 more source

Detection of Fungal Translocation in Patients With Alcohol Use Disorder Using a Real‐Time PCR Assay

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT Gut microbiota plays a key role in triggering various diseases. However, translocation studies focus on bacteria, neglecting fungal elements, while fungi seem also involved in triggering various diseases. Aim of this study was to assess whether fungal elements were able to translocate in patients with AUD (alcohol use disorder) and to verify ...
Nathalie Pansu, Pascal Drakulovski, Donika Krasteva, Virginie Bellet, Jean‐Philippe Lavigne, Catherine Dunyach‐Remy, Florian Salipante, Alex Yahiaoui‐Martinez, Hélène Donnadieu‐Rigole, Sébastien Bertout   +9 more
wiley   +1 more source

Research Progress in the Treatment of Vaginitis With Bioactive Compounds: Targeting of Vaginal Microflora

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Mechanism diagram of the effect of herbal medicine on vaginitis. Herbal medicines mainly combat vaginitis by (A) inhibiting bacteria, (B) inhibiting fungi, (C) acting on the cilia of Trichomonas, (D) inhibiting virus replication, (E) repairing the mucosa, (F) enhancing immunity, and (G) maintaining the microecological balance.
Yongming Li, Huiyu Liu, Ruihan Li, Rong Li, Jiaqi Liu   +4 more
wiley   +1 more source

Taste Dysfunction in Oral Candidiasis: Impact of Candida Carriage and Hyphal Presence

Mycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Taste dysfunction is a common symptom of oral candidiasis; however, its underlying mechanisms remain unclear. Objectives This study aimed to determine whether Candida albicans carriage, particularly its hyphal phenotype, is associated with impaired taste sensitivity.
Younjung Park, Hyo‐Jung Jung, Sin Hye Hwang, Eunae Sandra Cho, Hyung‐Joon Ahn   +4 more
wiley   +1 more source