Results 51 to 60 of about 1,628 (159)

Candidalysin impedes the development of embryonic zebrafish (Danio rerio) [PDF]

, 2021
Abstract Candidalysin is a cytolytic peptide secreted by Candida albicans, an opportunistic human fungal pathogen that was widely spread in clinic and in the environment. However, its impacts on the development of aquatic organisms remain limited.
Jing Shen, JingCong Tan, Haochun Shi, Jie Zhou, Yanbin Zhao, Kun Zhang, Ning-Ning Liu, Hui Wang   +7 more
openaire   +1 more source

Gaining insights from Candida biofilm heterogeneity: one size does not fit all [PDF]

, 2018
Despite their clinical significance and substantial human health burden, fungal infections remain relatively under-appreciated. The widespread overuse of antibiotics and the increasing requirement for indwelling medical devices provides an opportunistic ...
Delaney, Christopher, Kean, Ryan, McLean, William, Metcalfe, Rebecca, Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Thomas, Rachael, Williams, Craig   +8 more
core   +4 more sources

Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping [PDF]

, 2016
This work was supported by the Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377/Z/11/Z. We are grateful to microbiology colleagues throughout Scotland for clinical isolates collection.Peer reviewedPublisher ...
Abeln, Sanne, Brandt, Bernd W., Burgess, Karl V, Heringa, Jaap, Jones, Brian L., Kean, Ryan, May, Ali, Munro, Carol A., Rajendran, Ranjith, Ramage, Gordon, Sherry, Leighann, Williams, Craig   +11 more
core   +4 more sources

Candida albicans Yeast, Pseudohyphal, and Hyphal Morphogenesis Differentially Affects Immune Recognition [PDF]

, 2017
The authors thank Amy Whittington for preliminary experiments on in vitro induction of pseudohyphae and Mihai Netea for discussions. The authors also thank Michael Weig for the pga29 strains. Funding NG and AW were supported by the Wellcome Trust (086827,
Bailey, Bates, Bates, Beaussart, Berman, Birse, Blasi, Brown, Bulawa, Calera, Cambi, Chen, Chen, Cheng, Cheng, Chiani, Courjol, Dalle, De Boer, Dennehy, d’Ostiani, Endres, Erwig, Fidel, Gantner, Gantner, Ghannoum, Gow, Gow, Gow, Gow, Gow, Gudlaugsson, Harris, Heinsbroek, Hobson, Hoebe, Hornby, Hornby, Hosseinzadeh, Jackson, Jouault, Kohatsu, Kullberg, Kullberg, Lee, Linden, Lo, Lu, Matuschak, McKenzie, Medzhitov, Merson-Davies, Mora-Montes, Mora-Montes, Moyes, Moyes, Moyes, Moyes, Munro, Murad, Netea, Netea, Netea, Pappas, Plaine, Rubin-Bejerano, Saville, Sellam, Sudbery, Sudbery, Sundstrom, Torosantucci, Van De Veerdonk, Van Der Graaf, Vavala, Wagener, Wheeler, Zhao, Zheng   +79 more
core   +2 more sources

The cell biology of the Trichosporon-Host interaction [PDF]

, 2017
Fungi of the genus Trichosporon are increasingly recognized as causative agents of superficial and invasive fungal disease in humans. Although most species are considered commensals of the human skin and gastrointestinal tract, these basidiomycetes are ...
Akoumianaki, Alby, Aratani, Arendrup, Arikawa, Arts, Bentubo, Cheng, Childers, Chitasombat, Choi, Colombo, Cong, Crawford, da Silva Dantas, de Almeida Junior, de Almeida Junior, Di Bonaventura, Ene, Ene, Erwig, Fernandes, Figueiredo-Carvalho, Fonseca, Fontaine, Gacser, Garlanda, Gish, Gouba, Gravelat, Gresnigt, Higashino-Kameda, Hole, Iliev, Karashima, Kontoyiannis, Kronstad, Krysan, Lamas, Lanternier, Lee, Li, Lyman, Lyman, Marine, Moalli, Monari, Moyes, Moylett, Muranaka, Nosanchuk, Pande, Picard, Piccioni, Quintin, Reddy, Richardson, Rieber, Rodriguez-Tudela, Rohatgi, Saeed, Sandai, Sasaki, Saunders, Schwartz, Sokol, Sriswasdi, Sugita, Sugita, Sun, Suzuki, Taylor-Smith, Thywißen, Walsh, Walsh, Wynne, Yauch, Zaragoza, Zelante, Zhang, Zhang, Zhang   +81 more
core   +1 more source

IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis [PDF]

, 2016
Signaling through the IL-17 receptor (IL-17R) is required to prevent oropharyngeal candidiasis (OPC) in mice and humans. However, the IL-17-responsive cell type(s) that mediate protection are unknown.
Brane, Lucas, Bruno, Vincent M., Childs, Erin E., Coleman, Bianca M., Conti, Heather R., Cruz, J. Agustin, Daugherty, Sean, Filler, Scott G., Gaffen, Sarah L., Garg, Abhishek V., Hendricks, Matthew R., Hise, Amy G., Hunter, Joseph P., Kolls, Jay K., Mengesha, Bemnet G., Naglik, Julian R., Richardson, Jonathan P., Saevig, Danielle L., Sinha, Satrajit, Solis, Norma, Verma, Akash H.   +20 more
core   +1 more source

The Dual Function of the Fungal Toxin Candidalysin during Candida albicans—Macrophage Interaction and Virulence

Toxins, 2020
The dimorphic fungus Candida albicans is both a harmless commensal organism on mucosal surfaces and an opportunistic pathogen. Under certain predisposing conditions, the fungus can overgrow the mucosal microbiome and cause both superficial and life ...
Annika König, Bernhard Hube, Lydia Kasper   +2 more
doaj   +1 more source

Recent trends in molecular diagnostics of yeast infections : from PCR to NGS [PDF]

, 2019
The incidence of opportunistic yeast infections in humans has been increasing over recent years. These infections are difficult to treat and diagnose, in part due to the large number and broad diversity of species that can underlie the infection.
Arastehfar, A, Boekhout, T, Buda De Cesare, G, Butler, G, Dolk, E, Gabaldón, Tony, Hafez, A, Hagen, F, Hovhannisyan, H, Hube, B, Iracane, E, Kostrzewa, M, Lackner, M, Lass-Flörl, C, Llorens, C, Mixão, V, Munro, C, Oliveira-Pacheco, J, OPATHY Consortium, the, Pekmezovic, M, Pérez-Hansen, A, Rodriguez Sánchez, Antonio, Sauer, FM, Sparbier, K, Stavrou, AA, Vaneechoutte, Mario, Vatanshenassan, M   +26 more
core   +2 more sources

Nucleic acids enrichment of fungal pathogens to study host-pathogen interactions [PDF]

, 2019
Fungal infections, ranging from superficial to life-threatening infections, represent a major public health problem that affects 25% of the worldwide population.
Coucke, Paul, Guillemyn, Brecht, Rodriguez Sánchez, Antonio, Vaneechoutte, Mario   +3 more
core   +1 more source

Medical mycology and fungal immunology : new research perspectives addressing a major world health challenge [PDF]

, 2016
N.A.R.G. is supported by grants from The Wellcome Trust and MRC. M.G.N. is supported by an ERC consolidator grant (no.
Brown GD, Jenkinson HF, Kennedy MJ, Mihai G. Netea, Neil A. R. Gow, Romani L, Van der Graaf CA   +6 more
core   +1 more source