Results 51 to 60 of about 1,214 (146)
Food Hydrocolloids for HealthPectin, a dietary fiber, exhibits anti-inflammatory properties influenced by its degree of methyl-esterification (DM). Inflammatory bowel disease (IBD) is characterized by chronic inflammation due to a compromised epithelial barrier, dysregulated ...
Naschla Gasaly +2 more
exaly +3 more sources
Exploring the role of candidalysin in the pathogenicity of Candida albicans by gene set enrichment analysis and evolutionary dynamics [PDF]
American Journal of Translational ResearchTo explore the pathogenic mechanisms of Candida albicans (C. albicans), focusing on its impact on human health, particularly through invasive infections in the gastrointestinal and respiratory tracts.In this study, we evaluated the demographic and clinical profiles of 7 pneumonia patients.
Xingchen, Zhou +5 more
openaire +3 more sources
Candidalysin impedes the development of embryonic zebrafish (Danio rerio) [PDF]
, 2021 Abstract Candidalysin is a cytolytic peptide secreted by Candida albicans, an opportunistic human fungal pathogen that was widely spread in clinic and in the environment. However, its impacts on the development of aquatic organisms remain limited.
Jing Shen +7 more
openaire +1 more source
Fungal Toxins and Host Immune Responses
Frontiers in Microbiology, 2021 Fungi are ubiquitous organisms that thrive in diverse natural environments including soils, plants, animals, and the human body. In response to warmth, humidity, and moisture, certain fungi which grow on crops and harvested foodstuffs can produce ...
Rhys Brown +3 more
doaj +1 more source
Candidalysin secretion is correlated with IL-1β release and damage.
, 2021 HiBiT-tagged candidalysin secretion (Fig 6H) was plotted against (A) IL-1β release (Fig 6F) and (B) LDH levels (Fig 6G). Linear regression analysis was conducted and r2 values calculated. (TIF)
Andrew C. Dixson (11419367) +16 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 The mucosal surfaces of the human body are challenged by millions of microbes on a daily basis. Co-evolution with these microbes has led to the development of plastic mechanisms in both host and microorganisms that regulate the balance between preserving
Aize Pellon +2 more
doaj +1 more source
, 2021 (A) In silico modeling of candidalysin from both SC5314 and 529L reveal dihelical peptides with relatively conserved structure. (B) Sulforhodamine B (SRB) loaded lipid vesicles were treated with WT and VAR candidalysin for 1 h and fluorescence intensity (
Andrew C. Dixson (11419367) +16 more
core +1 more source
PLoS Pathogens, 2021 Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide.
Junyan Liu +16 more
doaj +1 more source
Variant ECE1 is associated with reduced candidalysin secretion.
, 2021 (A) Schematic depicting C-terminal candidalysin HiBiT tag within the ECE1 open reading frame and general assay function. (B) Strains GP1 (untagged, open bars) or WOHBT (HiBiT tagged, closed bars) were grown in RPMI-1640 or YNB medium for 16 h ...
Andrew C. Dixson (11419367) +16 more
core +1 more source
mBio, 2018 Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, these ...
Stefanie Allert +16 more
doaj +1 more source