Results 21 to 30 of about 3,878,610 (315)

Identification of candidate genes for dyslexia susceptibility on chromosome 18 [PDF]

, 2010
Background: Six independent studies have identified linkage to chromosome 18 for developmental dyslexia or general reading ability. Until now, no candidate genes have been identified to explain this linkage.
Olson, R K, Pennington Bruce F., Anthony P. Monaco, Pennington, B F, Scerri, TS, Alex J. Richardson, Smith, SD, Talcott, J, Richard K. Olson, Alex J Richardson, MacPhie, I L, Joel Talcott, Bruce F Pennington, Stein, J, Monaco, AP, Morris Andrew, Pennington, BF, Olson Richard K., Silvia Paracchini, Macphie, IL, DeFries, J C, Anthony P Monaco, Thomas S Scerri, Smith, Shelley D., Richardson, Alex J., Olson, RK, I Laurence MacPhie, Stein, John, Shelley D. Smith, Pennington, Bruce F., Monaco, Anthony P., Defries, JC, Paracchini, Silvia, John Stein, Stein, John F., Scerri Thomas S., MacPhie I. Laurence, Talcott, Joel B., I. Laurence MacPhie, Richardson, Alexandra, Monaco, Anthony, Andrew Morris, John C. DeFries, Talcott Joel, Morris, Andrew, Smith, S D, Smith Shelley D., Talcott, Joel, Bruce F. Pennington, Monaco Anthony P., Olson, Richard K., MacPhie, I. Laurence, Morris, A, Richardson, AJ, Paracchini, S, DeFries, John C., DeFries John C., Shelley D Smith, Stein John, John C DeFries, Monaco, A P, Richard K Olson, Paracchini Silvia, Thomas S. Scerri, Scerri, Thomas S., Scerri, T S   +65 more
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Candidate and non-candidate genes in behavior genetics

Current Opinion in Neurobiology, 2013
In this review we discuss recent developments in psychiatric genetics: on the one hand, studies using whole genome approaches (genome-wide association studies (GWAS) and exome sequencing) are coming close to finding genes and molecular variants that contribute to disease susceptibility; on the other candidate genes, such as the serotonin transporter ...
Flint, Jonathan, Munafò, Marcus R
openaire   +5 more sources

The clinical, personality, and genetic correlates of binge drinking: A controlled association study from India

Journal of Mental Health and Human Behaviour, 2018
Background and Objectives: Reasonable amount of literature has been accumulated over the years to indicate that the binge drinkers might be different from the group which does not have any history of binging.
Abhishek Ghosh, Savita Malhotra, Debasish Basu, Madhu Khullar   +3 more
doaj   +1 more source

Unifying candidate gene and GWAS Approaches in Asthma. [PDF]

, 2010
The first genome wide association study (GWAS) for childhood asthma identified a novel major susceptibility locus on chromosome 17q21 harboring the ORMDL3 gene, but the role of previous asthma candidate genes was not specifically analyzed in this GWAS ...
Heinzmann, Andrea, Ruether, Andreas, Otto Laub, Bufe, A., Lathrop, M, Schedel, M., Michel, Sven, Ruether, A., Michel, S., Schreiber, Stefan, von Berg, A., Gut, I.G., Christian Vogelberg, Ernst Rietschel, von Mutius, E., Burkhard Simma, Schreiber, S., Klopp, N., Schedel, Michaela, Depner, Martin, Laub, O., Liang, Liming, Stefan Schreiber, Illig, T., Rietschel, E., Michael Kabesch, Gut, Ivo Glynne, Mutius, Erika von, Frischer, T., Kabesch, Michael, Kabesch, M., Lathrop, Mark, Frischer, Thomas, Ashish Kumar, Jon Genuneit, Gut, Ivo G., Albrecht Bufe, Mark Lathrop, Kumar, A., Rietschel, Ernst, Ivo G. Gut, Illig, Thomas, Martin Depner, Liming Liang, Heinzmann, A., Andrea von Berg, Laub, Otto, Thomas Illig, Andreas Ruether, Simma, B., Vogelberg, Christian, Bufe, Albrecht, Erika von Mutius, Simma, Burkhard, Ivo G Gut, Kumar, Ashish, Sven Michel, Liang, L.M., Depner, M., Berg, Andrea von, Thomas Frischer, Michaela Schedel, Genuneit, J., Genuneit, Jon, Vogelberg, C., Norman Klopp, Klopp, Norman, Andrea Heinzmann   +67 more
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Allelic distribution of BDNF Val66Met polymorphism in healthy Romanian volunteers

Translational Neuroscience, 2016
Population stratification of functional gene polymorphisms is a potential confounding factor in genetic association studies. The Val66Met (rs6265) single-nucleotide polymorphism in the brain-derived neurotrophic factor gene (BDNF) exhibits one of the ...
Vulturar Romana, Chiş Adina, Hambrich Melinda, Kelemen Beatrice, Ungureanu Loredana, Miu Andrei C.   +5 more
doaj   +1 more source

Deciphering the Genetic Alterations in PIK3CA Gene Interacting Network and Their Putative Association with Breast Cancer: A Computational Approach [PDF]

Middle East Journal of Cancer
Background: Cancer is a polygenic complex disorder involving a network of genes. The phosphatidylinositol 3-kinase (PIK3CA) has been reported as an oncogene that plays a role in many cancer types.
Sivapriya Dayakar, Anitha Pandi, Chandra Pandi, Paramasivam Arumugam, Vijayashree Priyadharsini Jayaseelan   +4 more
doaj   +1 more source

UBE2QL1 is Disrupted by a Constitutional Translocation Associated with Renal Tumor Predisposition and is a Novel Candidate Renal Tumor Suppressor Gene [PDF]

, 2013
Investigation of rare familial forms of renal cell carcinoma (RCC) has led to the identification of genes such as VHL and MET that are also implicated in the pathogenesis of sporadic RCC. In order to identify a novel candidate renal tumor suppressor gene,
Hodgson, S, Morris, Mark R., Turnell, Andrew S., Woodward, ER, Prigmore, Elena, Woodward, Emma R.; id_orcid, Wake, NC, Wake, Naomi C., Gribble, Susan M., Ricketts, Christopher J., Skytte, AB, Brown, Michael, Banks, RE, Morris, MR, Prigmore, E, Maher, ER, Woodward, Emma R., Clarke, Noel, Hodgson, Shirley, Skytte, Anne-bine, Ricketts, CJ, Turnell, AS, Brown, Michael; id_orcid, Maher, Eamonn R., Clarke, N, Banks, Rosamonde E., Gribble, SM, Brown, M, Skytte, Anne Bine, Wake, N, Clarke, Noel W, Brown, Michael D, Ricketts, C, Woodward, E, Skytte, A-B, Maher, E, Morris, M, Banks, R, Turnell, A, Gribble, S   +39 more
core   +1 more source

Variation in the autism candidate gene GABRB3 modulates tactile sensitivity in typically developing children [PDF]

, 2012
Background: Autism spectrum conditions have a strong genetic component. Atypical sensory sensitivities are one of the core but neglected features of autism spectrum conditions. GABRB3 is a well-characterised candidate gene for autism spectrum conditions.
Simon Baron-Cohen, Tavassoli Teresa, Bonnie Auyeung, Bhismadev Chakrabarti, Baron-Cohen, Simon, Laura C Murphy, Murphy Laura C, Murphy, Laura; id_orcid, Auyeung, Bonnie, Chakrabarti Bhismadev, Auyeung Bonnie, Murphy, Laura C., Baron-Cohen Simon, Auyeung, Bonnie; id_orcid, Teresa Tavassoli, Chakrabarti, Bhismadev, Tavassoli, Teresa, Chakrabarti, Bhisma   +17 more
core   +4 more sources

Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array [PDF]

, 2009
The outcome of Genome-Wide Association Studies (GWAS) has challenged the field of blood pressure (BP) genetics as previous candidate genes have not been among the top loci in these scans.
Döring, Angela, Illig, T, Peeter Juhanson, Katrin Kepp, Juhanson, P., Juhanson, P, Samani, Nilesh, Philip Howard, Caulfield, Mark J., P. B. Munroe (7602386), Veldre, G, Farrall, Martin, Lichtner Peter, Dobson, RJ, Viigimaa, M., C. Gieger (7609259), Morris Brown, Putku Margus, Wichmann, H.-E., Illig, T., Siim Sõber, Gudrun Veldre, Shaw-Hawkins, Sue, Kelgo, Piret, Illig Thomas, R. J. Dobson (7602557), Samani, N, Samani Nilesh, Laan, Maris, HYPertens ESTonia Study, A. Dominiczak (7611551), Munroe, Patricia B., Kepp, K, John Connell, T. Illig (7609322), Samani, N., M. Putku (7602647), Viigimaa Margus, Farrall Martin, Brown, M, Peter Lichtner, Sober, S, A. Döring (7609562), Lichtner, Peter, P. Howard (7611350), Piret Kelgo, Juhanson Peeter, Dobson, Richard J.; id_orcid, Org, E, Farrall, M, Dobson, R.J., Meitinger, T, Veldre, Gudrun, E. Org (7602644), Kooperative Gesundheitsforschung in der Region Augsburg Study, Lichtner, P., H-Erich Wichmann, Martin Farrall, Kepp, Katrin, Gieger, Christian, HYPertension in ESTonia Study, Margus Putku, Newhouse, SJ, Onipinla Abiodun, Caulfield Mark J., Meitinger, T., M. Laan (7602659), Caulfield, MJ, Maris Laan, Eyheramendy, S., Onipinla, A., Newhouse, S.J., M. Viigimaa (7602620), Gieger, C, Dominiczak, A., Kelgo, P, Onipinla, A, Döring Angela, Newhouse, Stephen J.; id_orcid, Shaw-Hawkins Sue, Susana Eyheramendy, Munroe, PB, Klopp, Norman, Newhouse, Stephen J., Brown, Morris, Putku, Margus, M. Farrall (6522599), Wichmann, H.-Erich, Meitinger Thomas, S. Eyheramendy (7611197), Wichmann, Heinz-Erich, Putku, M, M. Brown (3020991), Gieger, C., Christian Gieger, Döring, A., Dobson, Richard J., Munroe, P.B., Juhanson, Peeter, Lichtner, P, Richard J Dobson, Org, E., H-E. Wichmann (7611602), Doering, Angela, Howard Philip, Kepp, K., Org, Elin, Kelgo Piret, Anna Dominiczak, Klopp, N., S. Shaw-Hawkins (7602380), Org Elin, Gieger Christian, Dominiczak Anna, Margus Viigimaa, Viigimaa, Margus, Newhouse Stephen J., K. Kepp (7611593), Sue Shaw-Hawkins, Stephen J Newhouse, Howard, P., Munroe Patricia B., Wichmann, H. Erich, P. Kelgo (7611596), Wichmann H.-Erich, Eyheramendy, S, Kooperative Gesundheitsforsch, Putku, M., M. J. Caulfield (7602383), Patricia B Munroe, Howard, P, Angela Döring, Eyheramendy, Susana, Nilesh Samani, Veldre Gudrun, Kepp Katrin, Sõber Siim, J. . Connell (7611608), Wichmann, HE, MRC British Genet Hypertens Study, Laan, M., Laan Maris, Elin Org, Connell, J, Illig, Thomas, Meitinger, Thomas, Doring, A, Viigimaa, M, Thomas Illig, N. Klopp (7611599), S. J. Newhouse (7602371), Connell John, S. Sõber (7602650), Shaw-Hawkins, S, Onipinla, Abiodun, Shaw-Hawkins, S., Dobson Richard J., Dominiczak, A, Klopp Norman, T. Meitinger (14191), Abiodun Onipinla, G. Veldre (7602656), Sõber, Siim, Thomas Meitinger, Eyheramendy Susana, P. Lichtner (7611605), A. Onipinla (7602377), Mark J Caulfield, Klopp, N, Caulfield, M.J., N. Samani (7611611), P. Juhanson (7602641), Dominiczak, Anna, Veldre, G., Connell, J., Connell, John, Norman Klopp, MRC British Genetics of Hypertension Study, Brown, M., Sõber, S., Howard, Philip, Brown Morris, Laan, M, Sõber, S;Org, E;Kepp, K;Juhanson, P;Eyheramendy, S;Gieger, C;Lichtner, P;Klopp, N;Veldre, G;Viigimaa, M;Döring, A;Putku, M;Kelgo, P;Shaw-Hawkins, S;Howard, P;Onipinla, A;Dobson, RJ;Newhouse, SJ;Brown, M;Dominiczak, A;Connell, J;Samani, N;Farrall, M;Caulfield, MJ;Munroe, PB;Illig, T;Wichmann, HE;Meitinger, T;Laan, M   +183 more
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Bioinformatics methods for identifying candidate disease genes

Human Genomics, 2006
With the explosion in genomic and functional genomics information, methods for disease gene identification are rapidly evolving. Databases are now essential to the process of selecting candidate disease genes.
van Driel Marc A, Brunner Han G
doaj   +1 more source