Results 101 to 110 of about 1,412,180 (220)

Molecular Epidemiology and Antigenic Characterization of Seasonal Influenza Viruses Circulating in Nepal

Journal of Nepal Health Research Council, 2017
Background: Influenza is one of the public health burdens in Nepal and its epidemiology is not clearly understood. The objective of this study was to explore the molecular epidemiology and the antigenic characteristics of the circulating influenza ...
Bishnu Prasad Upadhyay, Prakash Ghimire, Masato Tashiro, Megha Raj Banjara   +3 more
doaj   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

The role of influenza neuraminidase transmembrane domain on budding and virus morphology [PDF]

, 2014
Influenza A virus neuraminidase (NA), a type II transmembrane glycoprotein plays a role in the cleavage of sialic acids and facilitating the release of mature virions from the surface of infected cells. NA has also previously been shown to play a role in
Roddy, Scott, Edward
core  

Berberine Hampers Influenza A Replication through Inhibition of MAPK/ERK Pathway

Viruses, 2020
Background: Berberine (BBR) is an isoquinoline alkaloid which exhibits a variety of biological and therapeutic properties, and has been reported by some to block replication of the influenza virus. However, contradictory results have also been presented,
Paweł Botwina, Katarzyna Owczarek, Zenon Rajfur, Marek Ochman, Maciej Urlik, Maria Nowakowska, Krzysztof Szczubiałka, Krzysztof Pyrc   +7 more
doaj   +1 more source

Real‐Time and Non‐Invasive Detection of Respiratory Viral Infections Using an Intelligent Odor Monitoring System (IOMS)

Advanced Science, Volume 13, Issue 51, 14 September 2026.
An intelligent odor monitoring system integrates an IVC animal model, gas sensor array, real‐time resistance readout, and machine‐learning analysis to continuously monitor infection‐associated odor changes. The platform captures longitudinal sensor responses, distinguishes infected from healthy states, and supports early‐stage respiratory viral ...
Yajie Shen, Weifeng Yuan, Long Li, Yucheng Zheng, Kenan Liu, Hegeng Li, Hua‐Yao Li, Yongliang Zhao, Binzhou Ying, Lanpeng Guo, Wenjian Zhang, Shu‐Ming Kuo, Zirui Zhang, Yufan Deng, Bohan Yin, Zhaocheng Luo, Ke Xu, Huan Liu   +17 more
wiley   +1 more source

Enhanced replication of avian-origin H3N2 canine influenza virus in eggs, cell cultures and mice by a two-amino acid insertion in neuraminidase stalk

Veterinary Research, 2016
Canine influenza virus (CIV) is a newly identified, highly contagious respiratory pathogen in dogs. Recent studies indicate that avian-origin H3N2 CIV are circulating in Chinese dogs.
Yan Lin, Xing Xie, Yan-Bing Zhao, D. Kalhoro, Cheng-Ping Lu, Yong-Jie Liu   +5 more
semanticscholar   +1 more source

A functional link between the actin cytoskeleton and lipid rafts during budding of filamentous influenza virions [PDF]

, 2002
Morphogenesis of influenza virus is a poorly understood process that produces two types of enveloped virion: approximately 100-nm spheres and similar diameter filaments that reach 20 microm in length. Spherical particles assemble at plasma membrane lipid
Paul Digard, Simpson-Holley, Martha, McCauley, John, Debra Elton, Ellis, Darren, John McCauley, Darren Ellis, Digard, Paul, Martha Simpson-Holley, Fisher, Dawn, Elton, Debra, Dawn Fisher   +11 more
core   +1 more source

Efficacy of the Canine Influenza Virus H3N8 Vaccine To Decrease Severity of Clinical Disease after Cochallenge with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus [PDF]

Clinical and Vaccine Immunology, 2011
ABSTRACTSince first emerging in the North American canine population in 2004, canine influenza virus (CIV) subtype H3N8 has shown horizontal transmission among dogs, with a high level of adaptation to this species. The severity of disease is variable, and coinfection by other respiratory pathogens is an important factor in the degree of morbidity and ...
Laurie J, Larson, Jamie, Henningson, Patricia, Sharp, Bliss, Thiel, Muralidhar S, Deshpande, Tamara, Davis, Huchappa, Jayappa, Terri, Wasmoen, Nallakannu, Lakshmanan, Ronald D, Schultz   +9 more
openaire   +2 more sources

Deep Mutational Scanning for the Study and Engineering of Protein Assemblies

Chemistry–Methods, Volume 6, Issue 8, August 2026.
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger, Shoili Banerjee, Carolyn E. Mills   +2 more
wiley   +1 more source

Virus-like particle vaccine protects against H3N2 canine influenza virus in dog [PDF]

Vaccine, 2013
In the present study, virus-like particles (VLPs) were evaluated as a candidate veterinary vaccine against canine influenza virus (CIV) subtype H3N2. Specific pathogen-free (SPF) beagle dogs received a single injection of a VLP vaccine containing hemagglutinin (HA) and M1 protein of CIV H3N2 (H3 HA VLP). The vaccine was tested at 3 different doses with
Dong-Hun, Lee, Sang-Woo, Bae, Jae-Keun, Park, Jung-Hoon, Kwon, Seong-Su, Yuk, Jae-Min, Song, Sang-Moo, Kang, Yong-Kuk, Kwon, Hwi-Yool, Kim, Chang-Seon, Song   +9 more
openaire   +2 more sources