Results 91 to 100 of about 1,412,180 (220)

Multiplex Detection of Five Canine Viral Pathogens for Dogs as Laboratory Animals by the Luminex xTAG Assay

Frontiers in Microbiology, 2018
More and more dogs have been used as a disease model for medical research and drug safety evaluation. Therefore, it is important to make sure that the dogs and their living houses are special pathogen free.
Miaoli Wu, Miaoli Wu, Feng Cong, Yujun Zhu, Yuexiao Lian, Meili Chen, Ren Huang, Pengju Guo   +7 more
doaj   +1 more source

High yield production of influenza virus in Madin Darby canine kidney (MDCK) cells with stable knockdown of IRF7. [PDF]

PLoS ONE, 2013
Influenza is a serious public health problem that causes a contagious respiratory disease. Vaccination is the most effective strategy to reduce transmission and prevent influenza.
Itsuki Hamamoto, Hiroshi Takaku, Masato Tashiro, Norio Yamamoto   +3 more
doaj   +1 more source

Safety, Immunogenicity, and Protective Efficacy of an H5N1 Chimeric Cold-Adapted Attenuated Virus Vaccine in a Mouse Model

Viruses, 2021
H5N1 influenza virus is a threat to public health worldwide. The virus can cause severe morbidity and mortality in humans. We constructed an H5N1 influenza candidate virus vaccine from the A/chicken/Guizhou/1153/2016 strain that was recommended by the ...
Weiyang Sun, Zhenfei Wang, Yue Sun, Dongxu Li, Menghan Zhu, Menglin Zhao, Yutian Wang, Jiaqi Xu, Yunyi Kong, Yuanguo Li, Na Feng, Tiecheng Wang, Yongkun Zhao, Songtao Yang, Yuwei Gao, Xianzhu Xia   +15 more
doaj   +1 more source

Bringing Gene Therapy Into Real World Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach, Pratima Chowdary, Margareth C. Ozelo   +2 more
wiley   +1 more source

A novel reassortant canine H3N1 influenza virus between pandemic H1N1 and canine H3N2 influenza viruses in Korea

Journal of General Virology, 2012
During recent canine influenza surveillance in South Korea, a novel H3N1 canine influenza virus (CIV) that is a putative reassortant between pandemic H1N1 2009 and H3N2 CIVs was isolated. Genetic analysis of eight genes of the influenza virus revealed that the novel H3N1 isolate presented high similarities (99.1–99.9 %) to pandemic influenza H1N1 ...
Daesub, Song, Hyoung-Joon, Moon, Dong-Jun, An, Hye-Young, Jeoung, Hyekwon, Kim, Min-Joo, Yeom, Minki, Hong, Jeong-Hyun, Nam, Seong-Jun, Park, Bong-Kyun, Park, Jin-Sik, Oh, Manki, Song, Robert G, Webster, Jeong-Ki, Kim, Bo-Kyu, Kang   +14 more
openaire   +2 more sources

Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. [PDF]

, 2011
Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1 ...
Michaelis, Martin, Sithisarn, Patchima, Leutz, Anke, Cinatl, Jindrich, Martin Michaelis, Geiler Janina, Patrizia Naczk, Geiler, Janina, Doerr, Hans Wilhelm, Naczk, Patrizia, Sithisarn Patchima, Anke Leutz, Janina Geiler, Patchima Sithisarn, Hans Wilhelm Doerr, Jindrich Cinatl, Doerr Hans Wilhelm, Naczk Patrizia, Cinatl Jindrich, Leutz Anke, Michaelis Martin   +20 more
core   +2 more sources

Cloning of the canine RNA polymerase I promoter and establishment of reverse genetics for influenza A and B in MDCK cells

Virology Journal, 2007
Background Recent incidents where highly pathogenic influenza A H5N1 viruses have spread from avian species into humans have prompted the development of cell-based production of influenza vaccines as an alternative to or replacement of current egg-based ...
Duke Gregory M, Wang Zhaoti
doaj   +1 more source

Computed tomographic characterisation and surgical management of a caudal mediastinal paraoesophageal abscess with associated pneumonia in a dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract An 8‐year‐old, entire, male German shorthaired pointer presented with acute respiratory distress, pyrexia and coughing following a period of boarding. Thoracic radiographs identified a caudal mediastinal mass effect with severe multilobar bronchopneumonia.
Yi Gu, Kyle L. Granger Jr., Alyson Frederick, Laura Roy‐Eitner, Stephanie Kline   +4 more
wiley   +1 more source

Multigram Scale Synthesis and Anti-Influenza Activity of 3-Indoleacetonitrile Glucosides

Natural Product Communications, 2020
Indole-3-acetonitrile-6- O-β - d -glucopyranoside 1 is a simple alkaloid with anti-influenza A virus activity extracted from Radix isatidis . Herein, a concise and practical total synthetic route of 1 was presented, starting from 6-benzyloxyindole on a ...
Jianghong Dong, Fengmei Yan, Shuang Li, Zewen Li, Yuanhang Qin   +4 more
doaj   +1 more source

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source