Results 71 to 80 of about 30,067 (209)

The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus. [PDF]

, 2013
BackgroundThe current study was conducted to establish animal models (including mouse and ferret) for the novel avian-origin H7N9 influenza virus.FindingsA/Anhui/1/2013 (H7N9) virus was administered by intranasal instillation to groups of mice and ...
Bao, Linlin, Chen, Ting, Deng, Wei, Gao, Kai, Huang, Lan, Li, Fengdi, Li, Yanhong, Liu, Jiangning, Lv, Qi, Qin, Chuan, Wei, Qiang, Xiang, Zhiguang, Xu, Lili, Xu, Yanfeng, Yao, Yanfeng, Yong, Weidong, Yu, Pin, Yuan, Jing, Zhang, Lianfeng, Zhu, Hua   +19 more
core   +3 more sources

Serological evidence of canine influenza virus infection in shelter dogs in Turkey [PDF]

Medycyna Weterynaryjna, 2018
Influenza virus infection is an important disease which occurs in humans and a variety of animals. Because of the wide host adaptation and segmented genome, there is always the possibility of mutations and interspecies transmission of the influenza virus. Our study is the first to draw attention to canine influenza infection in Turkey.
TİMURKAN, MEHMET ÖZKAN, KIRBAŞ, AKIN, AYDIN, HAKAN, AKTAŞ, MUSTAFA SİNAN, AYDIN, ÖMER, ACAR, GÜLİZAR   +5 more
openaire   +4 more sources

Investigating Influenza Virus Polymerase Activity in Feline Cells Based on the Influenza Virus Minigenome Replication System Driven by the Feline RNA Polymerase I Promoter

Frontiers in Immunology, 2022
Emerging influenza virus poses a health threat to humans and animals. Domestic cats have recently been identified as a potential source of zoonotic influenza virus.
Gang Lu, Feiyan Zheng, Jiajun Ou, Xin Yin, Shoujun Li, Shoujun Li, Shoujun Li   +6 more
doaj   +1 more source

Bringing Gene Therapy Into Real World Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach, Pratima Chowdary, Margareth C. Ozelo   +2 more
wiley   +1 more source

Implementing Pasteur's vision for rabies elimination: the evidence base and the needed policy actions [PDF]

, 2014
It has been 129 years since Louis Pasteur's experimental protocol saved the life of a child mauled by a rabid dog, despite incomplete understanding of the etiology or mechanisms by which the miracle cure worked (1).
Cleaveland, Sarah, Hampson, Katie, Lankester, Felix, Lembo, Tiziana, Palmer, Guy, Taylor, Louise   +5 more
core   +1 more source

Safety, Immunogenicity, and Protective Efficacy of an H5N1 Chimeric Cold-Adapted Attenuated Virus Vaccine in a Mouse Model

Viruses, 2021
H5N1 influenza virus is a threat to public health worldwide. The virus can cause severe morbidity and mortality in humans. We constructed an H5N1 influenza candidate virus vaccine from the A/chicken/Guizhou/1153/2016 strain that was recommended by the ...
Weiyang Sun, Zhenfei Wang, Yue Sun, Dongxu Li, Menghan Zhu, Menglin Zhao, Yutian Wang, Jiaqi Xu, Yunyi Kong, Yuanguo Li, Na Feng, Tiecheng Wang, Yongkun Zhao, Songtao Yang, Yuwei Gao, Xianzhu Xia   +15 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Inhibition of influenza virus replication by nitric oxide [PDF]

, 1999
Nitric oxide (NO) has been shown to contribute to the pathogenesis of influenza virus-induced pneumonia in mouse models. Here we show that replication of influenza A and B viruses in Mabin Darby canine kidney cells is severely ...
Baars, M.M.J.W. (Marianne), Fouchier, R.A.M. (Ron), Lijster, P. (Pim) de, Osterhaus, A.D.M.E. (Albert), Rimmelzwaan, G.F. (Guus)   +4 more
core  

Selective engagement of FcγRIV by a M2e-specific single domain antibody construct protects against influenza A virus infection [PDF]

, 2019
Lower respiratory tract infections, such as infections caused by influenza A viruses, are a constant threat for public health. Antivirals are indispensable to control disease caused by epidemic as well as pandemic influenza A.
Ballegeer, Marlies, Creytens, Sarah, De Vlieger, Dorien, Hengel, Hartmut, Hoffmann, Katja, Nerinckx, Wim, Remaut, Han, Saelens, Xavier, Schepens, Bert, Van Hoecke, Lien, Van Molle, Inge   +10 more
core   +2 more sources

Efficacy of the Canine Influenza Virus H3N8 Vaccine To Decrease Severity of Clinical Disease after Cochallenge with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus [PDF]

Clinical and Vaccine Immunology, 2011
ABSTRACTSince first emerging in the North American canine population in 2004, canine influenza virus (CIV) subtype H3N8 has shown horizontal transmission among dogs, with a high level of adaptation to this species. The severity of disease is variable, and coinfection by other respiratory pathogens is an important factor in the degree of morbidity and ...
Laurie J, Larson, Jamie, Henningson, Patricia, Sharp, Bliss, Thiel, Muralidhar S, Deshpande, Tamara, Davis, Huchappa, Jayappa, Terri, Wasmoen, Nallakannu, Lakshmanan, Ronald D, Schultz   +9 more
openaire   +2 more sources