Results 71 to 80 of about 17,326 (159)

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

open access: yesAdvanced Science, Volume 13, Issue 37, 3 July 2026.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel   +15 more
wiley   +1 more source

Immunogenicity of a Multi‐Epitope Influenza Composite Peptide Vaccine Targeting Human, Swine, and Avian Viruses: Advancing Pandemic Preparedness

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background The emergence of novel reassortant influenza A virus strains and zoonotic transmission to the human population is a critical factor in the development of a global pandemic, as exemplified by the 2009 swine flu pandemic and the ongoing threat of an H5N1 avian flu pandemic.
Nimisha Rikhi   +6 more
wiley   +1 more source

Efficacy of the Canine Influenza Virus H3N8 Vaccine To Decrease Severity of Clinical Disease after Cochallenge with Canine Influenza Virus and Streptococcus equi subsp. zooepidemicus [PDF]

open access: yesClinical and Vaccine Immunology, 2011
ABSTRACTSince first emerging in the North American canine population in 2004, canine influenza virus (CIV) subtype H3N8 has shown horizontal transmission among dogs, with a high level of adaptation to this species. The severity of disease is variable, and coinfection by other respiratory pathogens is an important factor in the degree of morbidity and ...
Laurie J, Larson   +9 more
openaire   +2 more sources

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

open access: yesAdvanced Science, Volume 13, Issue 31, 4 June 2026.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li   +5 more
wiley   +1 more source

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

open access: yesSmall, Volume 22, Issue 33, 12 June 2026.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito   +2 more
wiley   +1 more source

Influenza A(H6N1) Virus in Dogs, Taiwan

open access: yesEmerging Infectious Diseases, 2015
We determined the prevalence of influenza A virus in dogs in Taiwan and isolated A/canine/Taiwan/E01/2014. Molecular analysis indicated that this isolate was closely related to influenza A(H6N1) viruses circulating in Taiwan and harbored the E627K ...
Hui-Ting Lin   +4 more
doaj   +1 more source

Paracetamol prescribing to small animals by veterinarians in Australia and New Zealand

open access: yesAustralian Veterinary Journal, Volume 104, Issue 6, Page 327-333, June 2026.
Objective To describe the prescribing patterns of paracetamol by veterinarians in Australia and New Zealand. Methods An online survey was created and distributed to veterinarians in Australia and New Zealand over a 3‐month period (July–October 2024).
A Tse, W Chee, CJ Boyd, CR Sharp
wiley   +1 more source

Streamlined Synthesis and Structure–Activity Relationship Analysis of 2‐Amidothiophene‐3‐Carboxamides Targeting Influenza Polymerase PA‐PB1 Heterodimerization

open access: yesChemMedChem, Volume 21, Issue 10, 27 May 2026.
Development of a three‐step synthesis and replacement of the cycloheptyl moiety in cycloheptathiophene‐3‐carboxamide derivatives revealed how thiophene C‐5 substitutions modulate PA–PB1 inhibition, antiviral potency, and water solubility. The phenyl analog 9 delivered sub‐µM potency across multiple IV strains, while the methyl analog 5 achieved the ...
Tommaso Felicetti   +8 more
wiley   +1 more source

LITERATUR REVIEW : INTRODUCTION OF THE CANINE INFLUENZA VIRUS

open access: yesBuletin Veteriner Udayana
The Canine Influenza Virus (CIV) is a causative agent of flu in dogs and belongs to the highly mutable Type A influenza virus group, which also infects various animals and humans. Despite ongoing efforts to control it, genetic variations in Type A influenza viruses persist.
Fedri Rell   +7 more
openaire   +1 more source

Multiplex PCR methods for detection of several viruses associated with canine respiratory and enteric diseases.

open access: yesPLoS ONE, 2019
Viral respiratory and intestinal infections are the most common causes of canine viral illness. Infection with multiple pathogens occurs in many cases. Rapid diagnosis of these multiple infections is important for providing timely and effective treatment.
Xiangqi Hao   +9 more
doaj   +1 more source

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