Canine Interferon-Inducible Transmembrane Protein Is a Host Restriction Factor That Potently Inhibits Replication of Emerging Canine Influenza Virus [PDF]
Canine influenza virus (CIV) is an emerging virus that is associated with major hidden hazards to the canine population and public health. Until now, how canine uses its innate immunity to restrict CIV replication is seldomly investigated.
Gang Lu, Shoujun Li, Xin Yin
exaly +4 more sources
Characterization of Canine Influenza Virus A (H3N2) Circulating in Dogs in China from 2016 to 2018 [PDF]
Avian H3N2 influenza virus follows cross-host transmission and has spread among dogs in Asia since 2005. After 2015–2016, a new H3N2 subtype canine influenza epidemic occurred in dogs in North America and Asia.
Hongbin He, Ye Ge, Yuanguo Li
exaly +4 more sources
Spread of Canine Influenza A(H3N2) Virus, United States [PDF]
A canine influenza A(H3N2) virus emerged in the United States in February-March 2015, causing respiratory disease in dogs. The virus had previously been circulating among dogs in Asia, where it originated through the transfer of an avian-origin influenza virus around 2005 and continues to circulate.
Ian E.H. Voorhees +12 more
openaire +4 more sources
In VitroSusceptibility of Canine Influenza A (H3N8) Virus to Nitazoxanide and Tizoxanide [PDF]
Infection of dogs with canine influenza virus (CIV) is considered widespread throughout the United States following the first isolation of CIV in 2004. While vaccination against influenza A infection is a common and important practice for disease control, antiviral therapy can serve as a valuable adjunct in controlling the impact of the disease.
Laura V. Ashton +3 more
openaire +3 more sources
Temperature-Sensitive Live-Attenuated Canine Influenza Virus H3N8 Vaccine. [PDF]
ABSTRACT Canine influenza is a respiratory disease of dogs caused by canine influenza virus (CIV). CIV subtypes responsible for influenza in dogs include H3N8, which originated from the transfer of H3N8 equine influenza virus to dogs; and the H3N2 CIV, which is an avian-origin virus that adapted to infect dogs.
Nogales A +8 more
europepmc +5 more sources
Emergence and Characterization of a Novel Reassortant Canine Influenza Virus Isolated from Cats. [PDF]
Cats are susceptible to a wide range of influenza A viruses (IAV). Furthermore, cats can serve as an intermediate host, and transfer avian influenza virus (AIV) H7N2 to a veterinarian.
Zhao J, He W, Lu M, He H, Lai A.
europepmc +2 more sources
Molecular Characterization of an H3N2 Canine Influenza Virus Isolated from a Dog in Jiangsu, China, in 2025. [PDF]
To investigate the molecular characteristics of H3N2 canine influenza viruses circulating in Jiangsu, China, we isolated a H3N2 strain (A/Canine/Nanjing/CnNj01-2025) from a dog presenting with respiratory signs at the Veterinary Teaching Hospital of ...
Peng J +8 more
europepmc +2 more sources
Negative regulation of reassortant canine influenza virus replication and key site identification in porcine and ferret bronchial epithelial cell lines. [PDF]
The segmented nature and high mutability of the influenza virus RNA genome facilitate rapid mutation and reassortment, allowing the virus to breach host barriers and migrate between different species, potentially leading to unpredictable influenza ...
Guo J +13 more
europepmc +2 more sources
H3N2 canine influenza virus-like particle vaccine with great protection in beagle dogs. [PDF]
In 2016, a distinct branch of H3N2 canine influenza virus (CIV) emerged, which has mutations related to mammalian adaptation and has replaced previously prevalent strains. This branch poses a risk of zoonotic infection.
Ge F-f +7 more
europepmc +2 more sources
Genetic characterization of an H3N2 canine influenza virus strain in China in 2023-acquisition of novel human-like amino acid substitutions. [PDF]
Around 2005, influenza A virus (IAV) once again crossed species barriers and established a stable lineage within canine populations. Currently, avian-origin H3N2 canine influenza virus (CIV) is the only strain of influenza that is stably circulating in ...
Li S, Chu L, Zhang Y, Yu Y, Wang G.
europepmc +2 more sources

