Results 61 to 70 of about 29,888 (208)

Genetic Evolution and Molecular Selection of the HE Gene of Influenza C Virus [PDF]

, 2019
Influenza C virus (ICV) was first identified in humans and swine, but recently also in cattle, indicating a wider host range and potential threat to both the livestock industry and public health than was originally anticipated.
He, Wanting, Li, Gairu, Su, Shuo, Veit, Michael, Wang, Congcong, Wen, Baiqing, Xu, Qiuhua, Zhang, Letian, Zhang, Wenyan, Zhang, Xu, Zhou, Jiyong   +10 more
core   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Infectivity and pathogenicity of canine H3N8 influenza A virus in horses [PDF]

Influenza and Other Respiratory Viruses, 2010
Please cite this paper as: Yamanaka et al. (2010) Infectivity and pathogenicity of canine H3N8 influenza A virus in horses. Influenza and Other Respiratory Viruses 4(6), 345–351.Background  Equine H3N8 influenza A viruses (EIVs) cause respiratory disease in horses and circulate among horses worldwide.
Yamanaka, Takashi, Tsujimura, Koji, Kondo, Takashi, Matsumura, Tomio, Ishida, Hideharu, Kiso, Makoto, Hidari, Kazuya I. P. J., Suzuki, Takashi   +7 more
openaire   +2 more sources

Elucidating the phylodynamics of endemic rabies virus in eastern Africa using whole-genome sequencing [PDF]

, 2015
Many of the pathogens perceived to pose the greatest risk to humans are viral zoonoses, responsible for a range of emerging and endemic infectious diseases.
Biek, Roman, Brunker, Kirstyn, Cleaveland, Sarah, Fooks, AR, Hampson, Katie, Horton, Daniel L, Kazwala, Rudovick, Lembo, Tiziana, Marston, Denise A, Mtema, Zacharia J, Ngeleja, Chanasa, Sambo, Maganga, Sikana, Lwitiko, Wilkie, Gavin   +13 more
core   +1 more source

Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons

Advanced Science, EarlyView.
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen‐xia Tian, Longlong Si   +14 more
wiley   +1 more source

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]

, 2014
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Barclay, Wendy S., Bean, Thomas J., Bruce, Christine, Carroll, Miles W., Dimmock, N. J., Dove, Brian K., Dowall, Stuart, Easton, A. J. (Andrew J.), Hallis, Bassam, Marriott, Anthony C., Newman, Edmund, Pearson, Geoff, Plank, Jenna, Rayner, Emma, Ryan, Kathryn A., Silman, Nigel J., Taylor, Irene, Whittaker, Catherine J.   +17 more
core   +6 more sources

Viral characterization of the reassortants between canine influenza H3N2 and human pandemic (2009) H1N1 and avian H9N2 viruses in canine ex vivo tracheal explants

Virology Journal
Background In 2007, the canine influenza H3N2 virus (H3N2-CIV) first emerged in the canine population in South Korea. The virus had since spread internationally and continues to circulate in the canines.
Tonia T. Kam, Christine H. T. Bui, Hin-Wo Yeung, Peter C. H. Wong, Alex W. H. Chin, John M. Nicholls, Malik Peiris, Kenrie P. Y. Hui, Leo L. M. Poon, Michael C. W. Chan   +9 more
doaj   +1 more source

A Multiplex RT-PCR Assay for Detection and Differentiation of Avian-Origin Canine H3N2, Equine-Origin H3N8, Human-Origin H3N2, and H1N1/2009 Canine Influenza Viruses. [PDF]

PLoS ONE, 2017
Virological and serological surveys have documented that H1N1/2009, avian-origin canine H3N2 (cH3N2), seasonal human-origin H3N2 (hH3N2), and equine-origin H3N8 influenza viruses are consistently circulating in dogs.
Chenxi Wang, Qian Wang, Junyi Hu, Honglei Sun, Juan Pu, Jinhua Liu, Yipeng Sun   +6 more
doaj   +1 more source

Investigating Influenza Virus Polymerase Activity in Feline Cells Based on the Influenza Virus Minigenome Replication System Driven by the Feline RNA Polymerase I Promoter

Frontiers in Immunology, 2022
Emerging influenza virus poses a health threat to humans and animals. Domestic cats have recently been identified as a potential source of zoonotic influenza virus.
Gang Lu, Feiyan Zheng, Jiajun Ou, Xin Yin, Shoujun Li, Shoujun Li, Shoujun Li   +6 more
doaj   +1 more source

An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism. [PDF]

, 2016
Influenza viruses cause seasonal flu each year and pandemics or epidemic sporadically, posing a major threat to public health. Recently, a new influenza D virus (IDV) was isolated from pigs and cattle. Here, we reveal that the IDV utilizes 9-O-acetylated
Chen, Xi, Diaz, Sandra, Gao, George F, Khedri, Zahra, Qi, Jianxun, Shi, Yi, Song, Hao, Varki, Ajit, Yu, Hai   +8 more
core   +3 more sources