Results 51 to 60 of about 1,736,990 (170)

mTOR pathway as a potential therapeutic target for cancer stem cells in canine mammary carcinoma

Frontiers in Oncology, 2023
Mammary adenocarcinoma, the most common cancer in female dogs, often exhibits the lymph node and lung metastases and has a higher mortality rate. However, mammary adenocarcinoma has no established treatment, except early surgical excision. Canine mammary
Masaki Michishita, Masaki Michishita, Kazuhiko Ochiai, Kazuhiko Ochiai, Rei Nakahira, Daigo Azakami, Yukino Machida, Tomokazu Nagashima, Takayuki Nakagawa, Toshiyuki Ishiwata   +9 more
doaj   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Evaluation of the expression of matrix metalloproteinase 9 and neutrophil gelatinase associated lipocalin in serum, urine and tumoral tissues of female dogs suffering from mammary gland tumors [PDF]

, 2013
In human medicine, it has been shown recently that the level of expression of matrix metalloproteinase-9 (MMP-9) and neutrophil gelatinase-associated lipocalin (NGAL) in serum, urine, and breast tissue were significantly increased in patients with breast
Belot, Guillaume
core  

Mouse Mammary Tumor Virus-Like Nucleotide Sequences in Canine and Feline Mammary Tumors [PDF]

Journal of Clinical Microbiology, 2010
ABSTRACT Mouse mammary tumor virus (MMTV) has been speculated to be involved in human breast cancer. Companion animals, dogs, and cats with intimate human contacts may contribute to the transmission of MMTV between mouse and human. The aim of this study was to detect MMTV-like nucleotide sequences in canine and feline mammary tumors by nested
Wei-Li, Hsu, Hsing-Yi, Lin, Shyan-Song, Chiou, Chao-Chin, Chang, Szu-Pong, Wang, Kuan-Hsun, Lin, Songkhla, Chulakasian, Min-Liang, Wong, Shih-Chieh, Chang   +8 more
openaire   +2 more sources

A study on the relationship between tumor size, tumor grade and lymph node involvement in canine mammary cancer: Simulation of tumor behavior in human breast cancer

Basic & Clinical Cancer Research, 2021
Background: In the last two decades, canine mammary cancer has played an important role in human breast cancer research. In many cases, there are various similarities between the biological and clinical features of canine breast cancer and female breast ...
Sanaz Rismanchi, Pejman Mortazavi, Samad Muhammadnejad   +2 more
doaj  

Inhibiting autophagy potentiates the antitumor efficacy of Euphorbia royleana for canine mammary gland tumors

BMC Veterinary Research, 2020
Background Canine mammary gland tumors (cMGTs) are the most common neoplasms in intact female canines and viewed as a suitable model for studying human breast cancers. Euphorbia royleana has been reported to have a variety of antitumor efficacies.
Yu-Ya Huang, Chia-Hung Chen, Chia-Hui Hsu, Tsun-Yung Kuo, Cheng-Chi Liu, Albert Tai-Ching Liao, Chen-Si Lin   +6 more
doaj   +1 more source

Labeling Strategies for Monitoring Cytoskeleton Dynamics in Cultured Epithelial Cells

Cytoskeleton, EarlyView.
ABSTRACT Collective cell migration relies on coordinated cytoskeletal remodeling, yet the impact of live‐cell actin filament probes on these dynamics remains poorly characterized. Here, we systematically compared the performance and cellular effects of fluorogenic jasplakinolide‐based probes, SiR‐actin and SiR‐XActin, with the genetically encoded ...
Victoria Levario‐Diaz, Lakshmi Nyapathi‐Gopinath, Jonah Luka Voigt, Katharina Weber, Marlene Maager, Veselin Nasufovic, Elisabetta Ada Cavalcanti‐Adam   +6 more
wiley   +1 more source

Protective Effect of HER2 Gene Polymorphism rs24537331 in the Outcome of Canine Mammary Tumors

Animals, 2023
The role of HER2 in canine mammary tumors is not completely elucidated, and the contradictory results published so far may be, in part, explained by the genetic variability recognized in the canine HER2 gene. Single nucleotide polymorphism (SNPs) in HER2
Ana Canadas-Sousa, Marta Santos, Patrícia Dias-Pereira   +2 more
doaj   +1 more source

Thrombocytosis and tumour distribution predict outcome in dogs with hepatocellular carcinoma: A multi‐institutional retrospective analysis

Veterinary Record, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is the most common canine hepatobiliary tumour. This study aimed to determine which criteria influenced outcome of HCC in a modern population of dogs across eight institutions. Methods The medical records of 106 dogs with HCC were retrospectively reviewed.
Emily A. Janik, MacKenzie A. Pellin, Dawn M. Clarke   +2 more
wiley   +1 more source

Canine desexing attitudes and practices of Australian veterinarians: A cross‐sectional survey

Australian Veterinary Journal, EarlyView.
Canine desexing is one of the most common small animal surgical procedures in Australia, yet little is known about current practices. This study characterised attitudes, practitioner recommendations and surgical practices for routine canine desexing among Australian veterinarians using an online cross‐sectional survey (n = 107). Respondent demographics
S. Impey, M. Blevins, G. Chung, A. Goh, P. Rak   +4 more
wiley   +1 more source