Results 71 to 80 of about 1,736,990 (170)

Estrogen receptors genotypes and canine mammary neoplasia

BMC Veterinary Research, 2019
Background Estrogens are essential for the development and proper function of several hormone-dependent organs. There are, however, several lines of evidence associating estrogens with mammary carcinogenesis.
Ana Canadas-Sousa, Marta Santos, Bárbara Leal, Rui Medeiros, Patrícia Dias-Pereira   +4 more
doaj   +1 more source

Safety and Feasibility of Infusing Ex Vivo Expanded Allogeneic Canine Natural Killer Cells for the Treatment of Metastatic Solid Tumours

Veterinary and Comparative Oncology, Volume 24, Issue 4, Page 745-755, December 2026.
ABSTRACT Companion canines need advances in therapeutic options for solid tumour malignancies. Natural killer (NK) cell infusions offer a promising treatment modality in canines with solid tumours. Autologous natural killer products are limited by dysfunctional immunity and a manufacturing process that delays care whereas allogeneic NK cells offer the ...
Allison M. Weisnicht, Fernanda Szewc, Monica Moonkyung Cho, Han‐Yun Hannah Cheng, Swetha Ganesh, Lauren Mahoney, Kathryn Fox, Portia R. Smith, Mallery Olsen, Rebecca M. Richards, David M. Vail, Christian M. Capitini   +11 more
wiley   +1 more source

Hormone Receptor Expression Analyses in Neoplastic and Non-Neoplastic Canine Mammary Tissue by a Bead Based Multiplex Branched DNA Assay: A Gene Expression Study in Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Samples. [PDF]

PLoS ONE, 2016
Immunohistochemistry (IHC) is currently considered the method of choice for steroid hormone receptor status evaluation in human breast cancer and, therefore, it is commonly utilized for assessing canine mammary tumors.
Annika Mohr, Florenza Lüder Ripoli, Susanne Conradine Hammer, Saskia Willenbrock, Marion Hewicker-Trautwein, Zdzisław Kiełbowicz, Hugo Murua Escobar, Ingo Nolte   +7 more
doaj   +1 more source

Expression of Topoisomerase II Alpha in Canine Colorectal Polyps, Adenomas and Adenocarcinomas

Veterinary and Comparative Oncology, Volume 24, Issue 4, Page 781-789, December 2026.
ABSTRACT With the development and increased accessibility of diagnostic methods in veterinary medicine, the possibilities for early detection of proliferative lesions in the canine large intestine have expanded over the past decade. Since in human medicine, topoisomerase II alpha (Topo IIα) is considered a prognostic and predictive marker in various ...
Joanna Fiedorowicz, Katarzyna Paździor‐Czapula, Paweł Antoni Kołodziejski, Iwona Otrocka‐Domagała   +3 more
wiley   +1 more source

Overexpression of α-enolase correlates with poor survival in canine mammary carcinoma

BMC Veterinary Research, 2011
Background α-Enolase (ENO1) is a key glycolytic enzyme implicated in the development of many human cancers including breast cancer. Increased expression of ENO1 has recently been reported in estrogen (ER)-positive human breast cancer patients.
Shih Neng-Yao, Liao Albert T, Hsu Nicholas C, Chu Pei-Yi, Hou Ming-Feng, Liu Chen-Hsuan   +5 more
doaj   +1 more source

Mitochondria in Viral Infections: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 11, November 2026.
Viral infections remodel mitochondrial function through direct viral regulation and infection‐induced changes in host cellular processes. These alterations affect OXPHOS, mitochondrial metabolism, calcium homeostasis, membrane potential, redox regulation, dynamics, and apoptosis, with distinct effects on viral replication and host antiviral responses ...
Ha Young Oh, Hye Jin Shin
wiley   +1 more source

Significance of ERα, HER2, and CAV1 expression and molecular subtype classification to canine mammary gland tumor [PDF]

, 2013
2013 Spring.Includes bibliographical references.Canine mammary gland tumor and human breast cancer share many similar features regarding their risk factors, histopathological features, and behavior.
Hanneman, William H., advisor, Shinoda, Hitomi, author, Legare, Marie E., committee member, Mason, Gary L., committee member   +3 more
core  

The Expression of Intermediate Filaments in Canine Mammary Glands and Their Tumors [PDF]

Veterinary Pathology, 1989
Monoclonal antibodies specific for different types of intermediate filaments (cytokeratin, vimentin, desmin and neurofilaments) were used to study the histogenesis of canine mammary glands and 57 canine mammary tumors by immunocytochemistry. The intra- and interlobular duct epithelium, acinar, and intralobular myoepithelial cells stained positively for
E, Hellmén, A, Lindgren
openaire   +2 more sources

Quantitative analysis of HER2 mRNA expression by RNA in situ hybridization in canine mammary gland tumors: Comparison with immunohistochemistry analysis.

PLoS ONE, 2020
Spontaneously occurring canine mammary gland tumors share many features with human breast cancer, including biological behavior and histologic features.
Byung-Joon Seung, Seung-Hee Cho, Soo-Hyeon Kim, Ha-Young Lim, Jung-Hyang Sur   +4 more
doaj   +1 more source

Overexpression of Mucin 1 Suppresses the Therapeutical Efficacy of Disulfiram against Canine Mammary Tumor

Animals, 2020
Mucin 1 (MUC1), a transmembrane protein, is closely associated with the malignancy and metastasis of canine mammary tumors; however, the role of overexpressed MUC1 in the development of cancer cells and response to drug treatment remains unclear.
Ying Zhao, Zixiang Lin, Zhaoyan Lin, Chaoyu Zhou, Gang Liu, Jiahao Lin, Di Zhang, Degui Lin   +7 more
doaj   +1 more source