Results 111 to 120 of about 46,891 (297)

Analytical Approaches to Address Challenges in the Analysis of Cannabinoids in Vascular Matrices Using Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud, Robert B. Laprairie, Anas El‐Aneed   +2 more
wiley   +1 more source

Lipid Nanoparticle Formulations for the Skin Delivery of Cannabidiol

Pharmaceutics
Background/Objectives: The aims of this work were to formulate cannabidiol in different lipid carriers for skin delivery after topical application and to study their stability, interaction with the skin, and antibacterial activity.
Maria Natalia Calienni, Mirian Ana Scavone, Ana Paula Sanguinetti, Merlina Corleto, Magalí Rocío Di Meglio, Pablo Raies, Diego Sebastián Cristos, Paulo César Maffia, Jorge Montanari   +8 more
doaj   +1 more source

Cannabidiol as a Promising Strategy to Treat and Prevent Movement Disorders?

Frontiers in Pharmacology, 2018
Movement disorders such as Parkinson's disease and dyskinesia are highly debilitating conditions linked to oxidative stress and neurodegeneration. When available, the pharmacological therapies for these disorders are still mainly symptomatic, do not ...
Fernanda F. Peres, Fernanda F. Peres, Alvaro C. Lima, Jaime E. C. Hallak, Jaime E. C. Hallak, José A. Crippa, José A. Crippa, Regina H. Silva, Vanessa C. Abílio, Vanessa C. Abílio   +9 more
doaj   +1 more source

Movement Disorders in Developmental and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Monogenic developmental and epileptic encephalopathies (DEE) frequently feature co‐occurring movement disorders. Gene discovery has expanded epilepsy‐dyskinesia syndromes (EDS) from classic associations such as stereotypies in Rett syndrome to PRRT2‐related infantile seizures with paroxysmal dyskinesia and crouched gait in SCN1A ...
Shekeeb Mohammad, Darius Ebrahimi‐Fakhari, Hugo Morales‐Briceno   +2 more
wiley   +1 more source

The Incredible Edible: Protecting Businesses and Consumers in a Society of Legalized Cannabis

, 2020
This Article briefly discusses the history and origin of marijuana, or more precisely the cannabis plant, before branching into an examination of its chemical properties, forms, and uses.
Thompson, Brandon M
core  

Potential Clinical Impact of Cannabidiol (CBD) in Canine and Feline Behavior: An Open-label Clinical Trial

, 2021
Chie Mogi, Takaaki Fukuyama
openalex   +2 more sources

Gray Matter Volume Loss in Parkinson's Disease Psychosis and Cannabinoid Receptor Gene Expression in the Brain

Movement Disorders, EarlyView.
Abstract Background Serotonergic and dopaminergic pathways are implicated in Parkinson's disease psychosis (PDP), but preliminary evidence also implicates the endocannabinoid system (ECS). Objectives We examined the association of gray matter volume loss in PDP patients with brain expression of the genes coding for CB1 (cannabinoid type 1) and CB2 ...
Sara Pisani, František Váša, Latha Velayudhan, Sagnik Bhattacharyya   +3 more
wiley   +1 more source

Cannabinoids in neurology – Brazilian Academy of Neurology

Arquivos de Neuro-Psiquiatria, 2015
The use of cannabidiol in some neurological conditions was allowed by Conselho Regional de Medicina de São Paulo and by Agência Nacional de Vigilância Sanitária (ANVISA).
Sonia M. D. Brucki, Norberto Anísio Frota, Pedro Schestatsky, Adélia Henriques Souza, Valentina Nicole Carvalho, Maria Luiza Giraldes Manreza, Maria Fernanda Mendes, Elizabeth Comini-Frota, Cláudia Vasconcelos, Vitor Tumas, Henrique B. Ferraz, Egberto Barbosa, Mauro Eduardo Jurno   +12 more
doaj   +1 more source

Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa. [PDF]

, 2009
RNA isolated from the glands of a Delta(9)-tetrahydrocannabinolic acid (THCA)-producing strain of Cannabis sativa was used to generate a cDNA library containing over 100 000 expressed sequence tags (ESTs).
Dixon, Richard A, Gang, David R, He, Ji, Marks, M David, Omburo, Stephanie N, Soto-Fuentes, Wilfredo, Tian, Li, Weiblen, George D, Wenger, Jonathan P   +8 more
core  

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source