Results 31 to 40 of about 43,946 (263)

Oral cannabidiol (CBD) as add-on to paracetamol for painful chronic osteoarthritis of the knee: a randomized, double-blind, placebo-controlled clinical trialResearch in context

open access: yesThe Lancet Regional Health. Europe, 2023
Summary: Background: Painful knee osteoarthritis (KOA) is common, pharmacological treatment, however, is often hampered by limited tolerability. Cannabidiol, which preclinically showed anti-inflammatory, analgesic activity, could supplement established ...
Sibylle Pramhas   +6 more
doaj   +1 more source

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model. [PDF]

open access: yes, 2020
Dravet syndrome is a catastrophic epilepsy of childhood, characterized by cognitive impairment, severe seizures, and increased risk for sudden unexplained death in epilepsy (SUDEP).
Anvar, Mana   +3 more
core   +1 more source

Self-administration of edible Δ9-tetrahydrocannabinol and associated behavioral effects in mice [PDF]

open access: yes, 2019
Background With increasing access to legal cannabis across the globe, it is imperative to more closely study its behavioral and physiological effects.
Boehm, Stephen L., II   +3 more
core   +1 more source

Successful use of pure cannabidiol for the treatment of super-refractory status epilepticus

open access: yesEpilepsy and Behavior Case Reports, 2018
We present the case of a child with long-standing, super-refractory status epilepticus (SRSE) who manifested prompt and complete resolution of SRSE upon exposure to pure cannabidiol.
Rajsekar R. Rajaraman   +2 more
doaj   +1 more source

Cannabidiol Displays Proteomic Similarities to Antipsychotics in Cuprizone-Exposed Human Oligodendrocytic Cell Line MO3.13

open access: yesFrontiers in Molecular Neuroscience, 2021
Cannabidiol, a compound of Cannabis sativa, has been proposed as an alternative treatment of schizophrenia. Preclinical and clinical data have suggested that cannabidiol shares more similarity with atypical antipsychotics than typical, both of which are ...
Ana Caroline Brambilla Falvella   +12 more
doaj   +1 more source

Phytocannabinoids as novel therapeutic agents in CNS disorders [PDF]

open access: yes, 2012
The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has been used for thousands of years for both recreational and medicinal purposes.
Hill, Andrew J.   +3 more
core   +1 more source

Disposition of a single oral dose of a cannabidiol medication in healthy cats

open access: yesFrontiers in Veterinary Science, 2023
The historical use of the marijuana plant for medicinal purposes is long. One of the historical uses has been for the treatment of epilepsy. Recently, the Food and Drug Administration has approved a highly purified cannabidiol medication for the add on ...
Tom Jukier   +3 more
doaj   +1 more source

Cannabis and schizophrenia [PDF]

open access: yes, 2014
BACKGROUND Schizophrenia is a mental illness causing disordered beliefs, ideas and sensations. Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear
Gillies, Donna   +6 more
core   +1 more source

Medical use of cannabis: italian and european legislation [PDF]

open access: yes, 2018
This review illustrates some brief considerations of the medical use of cannabis recently issued in Italy. History and uses of cannabis throughout centuries and different countries are illustrated together with a description of botany and active ...
Di Luca, A.   +3 more
core   +1 more source

Evaluation of Two Commercially Available Cannabidiol Formulations for Use in Electronic Cigarettes [PDF]

open access: yes, 2016
Since 24 states and the District of Columbia have legalized marijuana in some form, suppliers of legal marijuana have developed Cannabis sativa products for use in electronic cigarettes (e-cigarettes). Personal battery powered vaporizers, or e-cigarettes,
Butler, Karen E.   +4 more
core   +2 more sources

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