Results 11 to 20 of about 40,497 (266)
Cancers, 2021 Cannabinoids, active components of the plant Cannabis sativa, had been used for centuries in ancient medicine as therapeutic remedies for a variety of conditions, before becoming stigmatized due to their psychoactive effects [...]
Marco Falasca, Mauro Maccarrone
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Cannabinoids in Pediatrics [PDF]
The Journal of Pediatric Pharmacology and Therapeutics, 2017 Despite its controversial nature, the use of medical marijuana and cannabis-derived medicinal products grows more popular with each passing year. As of November 2016, over 40 states have passed legislation regarding the use of either medical marijuana or cannabidiol products. Many providers have started encountering patients experimenting with cannabis
Christopher T, Campbell +2 more
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Cannabinoids and glaucoma [PDF]
British Journal of Ophthalmology, 2004 Glaucoma is one of the leading causes of blindness in the world. In spite of the diverse therapeutic possibilities, new and better treatments for glaucoma are highly desirable. Cannabinoids effectively lower the intraocular pressure (IOP) and have neuroprotective actions. Thus, they could potentially be useful in the treatment of glaucoma.
Azuara-Blanco, A. +2 more
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Cannabinoids and Epilepsy [PDF]
Neurotherapeutics, 2015 Cannabis has been used for centuries to treat seizures. Recent anecdotal reports, accumulating animal model data, and mechanistic insights have raised interest in cannabis-based antiepileptic therapies. In this study, we review current understanding of the endocannabinoid system, characterize the pro- and anticonvulsive effects of cannabinoids [e.g ...
Evan C, Rosenberg +3 more
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Ictal vocalizations in the Scn1a+/− mouse model of Dravet syndrome
Epilepsia Open, 2023 Objective Ictal vocalizations have shown diagnostic utility in epilepsy patients. Audio recordings of seizures have also been used for seizure detection. The present study aimed to determine whether generalized tonic–clonic seizures in the Scn1a+/− mouse
Lyndsey L. Anderson +4 more
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Frontiers in Plant Science, 2021 In the last decades, growing evidence showed the therapeutic capabilities of Cannabis plants. These capabilities were attributed to the specialized secondary metabolites stored in the glandular trichomes of female inflorescences, mainly phytocannabinoids
Carni Lipson Feder +9 more
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The Scientific World JOURNAL, 2002 Cannabis has a long history of consumption both for recreational and medicinal uses. Recently there have been significant advances in our understanding of how cannabis and related compounds (cannabinoids) affect the brain and this review addresses the current state of knowledge of these effects.
Irving, Andrew J. +2 more
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Cannabinoid and Hyperemesis [PDF]
Mayo Clinic Proceedings, 2012 To the Editor: We read with interest the article by Simonetto et al1 on cannabinoid hyperemesis (CH) that was published in the February 2012 issue of Mayo Clinic Proceedings. Indeed, this entity is underdiagnosed due to a lack of awareness. Marijuana users presenting to the emergency department with nausea, vomiting, and abdominal pain are a common ...
Pallawi, Torka, Rajeev, Sharma
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Medicinal Cannabis Prescribing in Australia: An Analysis of Trends Over the First Five Years
Frontiers in Pharmacology, 2022 A regulatory framework allowing legal access to medicinal cannabis (MC) products has operated in Australia since November 2016. MC prescribing by healthcare practitioners (HCPs) is primarily conducted through the Special Access Scheme - Category B (SAS-B)
Sara L. MacPhail +10 more
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Heteroadamantyl Cannabinoids [PDF]
Journal of Medicinal Chemistry, 2010 The aliphatic side chain plays a pivotal role in determining the cannabinergic potency of tricyclic classical cannabinoids. We have synthesized a series of analogues in which the C3 position is substituted either directly or through a one-carbon atom linker with an adamantylamine or with an oxa- or an oxazaadamantane. The oxaadamantane pharmacophore in
Darryl D, Dixon +8 more
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