Results 21 to 30 of about 59,439 (317)
Ictal vocalizations in the Scn1a+/− mouse model of Dravet syndrome
Epilepsia Open, 2023 Objective Ictal vocalizations have shown diagnostic utility in epilepsy patients. Audio recordings of seizures have also been used for seizure detection. The present study aimed to determine whether generalized tonic–clonic seizures in the Scn1a+/− mouse
Lyndsey L. Anderson +4 more
doaj +1 more source
Cannabinoid-inspired inhibitors of Autotaxin
, 2023 Autotaxin (ATX) is an enzyme primarily known for the production of lysophosphatidic acid. Being involved in the development of major human diseases, such as cancer and neurodegenerative diseases, the enzyme has been featured in multiple studies as a ...
Viet-Khoa, Tran-Nguyen +8 more
core +1 more source
Cannabinoid and Hyperemesis [PDF]
Mayo Clinic Proceedings, 2012 To the Editor: We read with interest the article by Simonetto et al1 on cannabinoid hyperemesis (CH) that was published in the February 2012 issue of Mayo Clinic Proceedings. Indeed, this entity is underdiagnosed due to a lack of awareness. Marijuana users presenting to the emergency department with nausea, vomiting, and abdominal pain are a common ...
Pallawi, Torka, Rajeev, Sharma
openaire +2 more sources
Medicinal Cannabis Prescribing in Australia: An Analysis of Trends Over the First Five Years
Frontiers in Pharmacology, 2022 A regulatory framework allowing legal access to medicinal cannabis (MC) products has operated in Australia since November 2016. MC prescribing by healthcare practitioners (HCPs) is primarily conducted through the Special Access Scheme - Category B (SAS-B)
Sara L. MacPhail +10 more
doaj +1 more source
The biosynthesis of the cannabinoids [PDF]
Journal of Cannabis Research, 2021 Abstract Cannabis has been integral to Eurasian civilization for millennia, but a century of prohibition has limited investigation. With spreading legalization, science is pivoting to study the pharmacopeia of the cannabinoids, and a thorough understanding of their biosynthesis is required to engineer strains with specific ...
M. Nazir Tahir +3 more
openaire +3 more sources
Understanding cannabinoid receptors: structure and function [PDF]
, 2018 The endocannabinoid system (ECS) consists of the endocannabinoids, cannabinoid receptors and the enzymes that synthesize and degrade endocannabinoids.
Słomski, Ryszard +4 more
core +1 more source
Enhanced Anandamide Plasma Levels in Patients with Complex Regional Pain Syndrome following Traumatic Injury: A Preliminary Report [PDF]
, 2009 The complex regional pain syndrome (CRPS) is a disabling neuropathic pain condition that may develop following injuries of the extremities. The pathogenesis of this syndrome is not clear; however, it includes complex interactions between the nervous and ...
Schelling, G. +15 more
core +1 more source
Co‐designing clinical trials alongside youth with chronic pain
Paediatric & Neonatal Pain, 2023 Youth have a right to participate in research that will inform the care that they receive. Engagement with children and young people has been shown to improve rates of enrollment and retention in clinical trials as well as reduce research waste.
Zina Zaslawski +8 more
doaj +1 more source
Roles of the Cannabinoid System in the Basal Ganglia in Parkinson’s Disease
Frontiers in Cellular Neuroscience, 2022 Parkinson’s disease (PD) is a neurodegenerative disease usually caused by neuroinflammation, oxidative stress and other etiologies. Recent studies have found that the cannabinoid system present in the basal ganglia has a strong influence on the ...
Mengya Wang, Huayuan Liu, Zegang Ma
doaj +1 more source
, 2020 The manuscript of a paper entitled "Interaction of Synthetic Cannabinoid Receptor Agonists with Cannabinoid Receptor I: Insights into Activation Molecular Mechanism".
Anton, Bashilov +5 more
core +1 more source