Results 41 to 50 of about 41,569 (168)

Cannabinoids and neuroinflammation [PDF]

British Journal of Pharmacology, 2004
Growing evidence suggests that a major physiological function of the cannabinoid signaling system is to modulate neuroinflammation. This review discusses the anti‐inflammatory properties of cannabinoid compounds at molecular, cellular and whole animal levels, first by examining the evidence for anti‐inflammatory effects of cannabinoids obtained using ...
Lisa, Walter, Nephi, Stella
openaire   +2 more sources

Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey

Journal of Eating Disorders
Background There are few effective treatments for eating disorders (EDs), and new interventions are urgently needed. The MEDication and other drugs For Eating Disorders (“MED–FED”) survey investigated the lived experience of adults with EDs regarding ...
Sarah-Catherine Rodan, Noah Meez, Sophie Lloyd-Hurwitz, Miguel A. Bedoya-Pérez, Anastasia Suraev, Natasha Sommer, Kayla Greenstien, Sarah Maguire, Iain S. McGregor   +8 more
doaj   +1 more source

Conspecific presence facilitates 22-kHz ultrasonic calls in male rats exposed to cat odor

Scientific Reports
Rats (Rattus norvegicus) exhibit defensive behaviors such as hiding, freezing, and fleeing when confronted with predators. They also may emit long-duration, flat frequency (~ 22-kHz), ultrasonic vocalizations (USVs) in response to predator detection ...
Miguel A. Bedoya-Pérez, Mehek F. Rahman, Iain S. McGregor   +2 more
doaj   +1 more source

Dendritic Cell Regulation by Cannabinoid-Based Drugs

Pharmaceuticals, 2010
Cannabinoid pharmacology has made important advances in recent years after the cannabinoid system was discovered. Studies in experimental models and in humans have produced promising results using cannabinoid-based drugs for the treatment of obesity and ...
Mattias Svensson, Puran Chen, Oscar Hammarfjord   +2 more
doaj   +1 more source

Pharmacological and physiological effects of cannabidiol: a dose escalation, placebo washout study protocol

BMC Neurology
Background Cannabinoids such as cannabidiol (CBD) exhibit anti-inflammatory properties and have the potential to act as a therapeutic following mild traumatic brain injury.
J. Patrick Neary, Jyotpal Singh, Jane Alcorn, Robert B. Laprairie, Payam Dehghani, Cameron S. Mang, Bruce H. Bjornson, Thomas Hadjistavropoulos, Holly A. Bardutz, Lanishen Bhagaloo, Zachary Walsh, Michael Szafron, Kim D. Dorsch, Elizabeth S. Thompson   +13 more
doaj   +1 more source

The Acute Effects of Cannabidiol on Physiological and Subjective Responses to Endurance Exercise: A Dose-Ranging Randomised Controlled Crossover Trial

Sports Medicine - Open
Background Athletes report using cannabidiol (CBD), a non-intoxicating constituent of Cannabis sativa L., to enhance post-exercise recovery and manage other health conditions (e.g., poor sleep, anxiety, concussion).
Ayshe Sahinovic, Namson S. Lau, Angelo Sabag, Rebecca Gordon, Amanda J. Cox, Katie Walker, Christopher Irwin, Ben Desbrow, Nathan Johnson, Paul J. Austin, Paul Haber, Iain S. McGregor, Danielle McCartney   +12 more
doaj   +1 more source

The Effect of Cannabidiol on Subjective Responses to Endurance Exercise: A Randomised Controlled Trial

Sports Medicine - Open
Background Exercise is known to improve health. However, it can be unpleasant, often inducing negative feelings, or ‘affect’. Cannabidiol (CBD), a non-intoxicating constituent of the cannabis plant, has been reported to enhance the subjective experience ...
Danielle McCartney, Christopher Irwin, Zeeta Bawa, Blake Palmer, Ayshe Sahinovic, Nathan Delang, Gregory R. Cox, Ben Desbrow, Namson S. Lau, Iain S. McGregor   +9 more
doaj   +1 more source

Effects of cannabidiol on psychosocial stress, situational anxiety and nausea in a virtual reality environment: a protocol for a single-centre randomised clinical trial

BMJ Open
Introduction The non-intoxicating plant-derived cannabinoid, cannabidiol (CBD), has demonstrated therapeutic potential in a number of clinical conditions. Most successful clinical trials have used relatively high (≥300 mg) oral doses of CBD.
Iain S McGregor, Richard Fox, Hamish MacDougall, Danielle McCartney, Zeeta Bawa, Miguel Bedoya-Pérez, Namson S Lau   +6 more
doaj   +1 more source

NSW cannabis medicines advisory service retrospective enquiry analysis to inform clinical guidance resource development

Neuropsychopharmacology Reports
Background An innovative New South Wales government funded statewide Cannabis Medicines Advisory Service (CMAS) operated between January 2018 and June 2022.
Myfanwy Graham, Edward Eden, Kelsey Maddison, Luise Lago, Samuel Allingham, Catherine J. Lucas, Jennifer Schneider, Jennifer H. Martin   +7 more
doaj   +1 more source

Cannabinoids [PDF]

Journal of Pain and Symptom Management, 2013
Paul, Howard, Robert, Twycross, John, Shuster, Mary, Mihalyo, Andrew, Wilcock   +4 more
openaire   +2 more sources