Results 21 to 30 of about 152,484 (372)
Asian Journal of Pharmaceutical Research and Health Care, 2022 Cannabidiol industrialization is expected to reach $20 billion in sales by 2024 due to a sudden rise in scientific interest in marijuana (cannabis) and its therapeutic potential. Cannabis has been utilized for thousands of years in both medicine and science.
Nicholas T. Lappas, Courtney M. Lappas
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BMC Pediatrics, 2018 Background Initial studies suggest pharmaceutical grade cannabidiol (CBD) can reduce the frequency of convulsive seizures and lead to improvements in quality of life in children affected by epileptic encephalopathies.
Darren Reithmeier +14 more
doaj +1 more source
Frontiers in Psychiatry, 2022 IntroductionSynthetic cannabinoid receptor agonists (SCRAs) are a diverse class of new psychoactive substances that have been associated with multiple instances and types of toxicity. Some SCRAs appear to carry a greater toxicological burden than others,
Richard C. Kevin +13 more
doaj +1 more source
Cannabinoid Receptor Involvement in Stress-Induced Cocaine Reinstatement: Potential Interaction with Noradrenergic Pathways [PDF]
, 2012 This study examined the role of endocannabinoid signaling in stress-induced reinstatement of cocaine seeking and explored the interaction between noradrenergic and endocannabinergic systems in the process.
Hillard, Cecilia J. +6 more
core +2 more sources
Endocannabinoid-related compounds in gastrointestinal diseases [PDF]
, 2018 The endocannabinoid system (ECS) is an endogenous signalling pathway involved in the control of several gastrointestinal (GI) functions at both peripheral and central levels.
Alessandra, D'Alessandro +7 more
core +1 more source
The evolution and comparative neurobiology of endocannabinoid signalling [PDF]
, 2012 CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A. +4 more
core +1 more source
Targeting Cannabinoid Receptors: Current Status and Prospects of Natural Products
International Journal of Molecular Sciences, 2020 Cannabinoid receptors (CB1 and CB2), as part of the endocannabinoid system, play a critical role in numerous human physiological and pathological conditions.
Dongchen An +3 more
semanticscholar +1 more source
Cannabinoid Hyperemesis Syndrome [PDF]
, 2015 Legalization of marijuana use will increase the number of people who will become long-term users. A prior medical record review study in Australia, in 2004, identified 19 chronic marijuana users who entered the emergency department with recurrent ...
Heise, Lynn
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Cannabinoid Ligands Targeting TRP Channels
Frontiers in Molecular Neuroscience, 2019 Transient receptor potential (TRP) channels are a group of membrane proteins involved in the transduction of a plethora of chemical and physical stimuli.
Chanté Muller, P. Morales, P. Reggio
semanticscholar +1 more source
Ictal vocalizations in the Scn1a+/− mouse model of Dravet syndrome
Epilepsia Open, 2023 Objective Ictal vocalizations have shown diagnostic utility in epilepsy patients. Audio recordings of seizures have also been used for seizure detection. The present study aimed to determine whether generalized tonic–clonic seizures in the Scn1a+/− mouse
Lyndsey L. Anderson +4 more
doaj +1 more source