Results 151 to 160 of about 2,668,334 (282)

Evaluation of phytocannabinoids from high-potency Cannabis sativa using in vitro bioassays to determine structure–activity relationships for cannabinoid receptor 1 and cannabinoid receptor 2

Medicinal Chemistry Research, 2014
Afeef S. Husni, C. McCurdy, M. Radwan, Safwat Ahmed, D. Slade, S. Ross, M. Elsohly, S. Cutler   +7 more
semanticscholar   +1 more source

Differential Alterations in Offset Analgesia and Conditioned Pain Modulation in Fibromyalgia: Evidence for Distinct Central Dysregulation

European Journal of Pain, Volume 30, Issue 3, March 2026.
ABSTRACT Background Chronic pain often involves abnormalities in central pain processing. Two commonly used experimental methods for central pain modulation are conditioned pain modulation (CPM) and offset analgesia (OA). However, it is uncertain how similar the underlying processes they measure are.
Yara Agbaria, Giris Jacob, Raz Preger, Jacob N. Ablin, Valerie Aloush, Haggai Sharon   +5 more
wiley   +1 more source

Cannabinoid Receptor 2 (CB2) in Macrophages: A Promising Clinical Target for Immune Disorders. [PDF]

Int J Mol Sci
Yoon HH, Grimsey NL.
europepmc   +1 more source

Milk Fat Globule Membrane Supplementation Attenuates Cognitive Impairment in APP/PS1 Mice via Suppressing Neuroinflammation in a Gut Microbiota‐Mediated Serum Resolvin D1/Anandamide Manner

Food Frontiers, Volume 7, Issue 2, March 2026.
MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong, Qichen Yuan, Min Du, Xiaohan Liu, Xueying Mao   +4 more
wiley   +1 more source

Synthesis and Pharmacological Characterization of a Novel Cannabinoid Receptor 1 Antagonist. [PDF]

ACS Omega
Bengoetxea de Tena I, Pereira-Castelo G, Martínez-Gardeazabal J, Moreno-Rodríguez M, Manuel I, Martínez C, Vaz B, González-Ricarte J, Álvarez R, Torres-Mozas A, Peccati F, Jiménez-Osés G, Rodríguez de Lera A, Rodríguez-Puertas R.   +13 more
europepmc   +1 more source

Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva, Maria Gabriely de Lima Silva, Eduardo S. Silva, Lucas Yure S. Silva, Renata Torres Pessoa, Silvio C. Alves‐Júnior, Jullyana S. S. Quintans, Laurent Picot, Irwin Rose A. Menezes, Lucindo J. Quintans‐Júnior   +9 more
wiley   +1 more source

Novel floxed cannabinoid receptor 2 mouse line combines knockout capability with dual fluorescent reporters. [PDF]

Front Pharmacol
Laloli KJ, Rentsch P, Stayte S, Vissel B.   +3 more
europepmc   +1 more source

Repeated Low-Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains Cannabinoid Receptor Type 1–Mediated Antinociceptive and Gastroprotective Effects

Journal of Pharmacology and Experimental Therapeutics, 2013
S. Kinsey, L. Wise, Divya Ramesh, R. Abdullah, D. Selley, B. Cravatt, A. Lichtman   +6 more
semanticscholar   +1 more source

Upstream CB1R Regulation of β‐Adrenergic Memory Consolidation

Hippocampus, Volume 36, Issue 2, March 2026.
ABSTRACT Object recognition memory (ORM) plays a key role in identifying familiar items and encoding episodic information. ORM consolidation depends on β‐adrenergic receptor (βAR) signaling and is associated with increased BDNF expression in the dorsal hippocampus.
Janine I. Rossato, Lucas Ribeiro, Thais Lima‐Silva, Raquel Araujo, Rodrigo Orvate, Anna Lyvia Azevedo, Nina Bevilaqua Cammarota, Ana Luizi Baracho, Livia Carneiro, Martín Cammarota   +9 more
wiley   +1 more source

Retraction Note: Crystal structures of agonist-bound human cannabinoid receptor CB₁. [PDF]

Nature
Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, Zhao S, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ.   +19 more
europepmc   +1 more source