eFood, Volume 7, Issue 3, June 2026.Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam +4 more
wiley +1 more source
Identification of the cannabinoid receptor 1 antagonist, ibipinabant, as a potent inhibitor of <i>Neisseria gonorrhoeae</i>. [PDF]
Antimicrob Agents ChemotherDove AS +3 more
europepmc +1 more source
New Zealand Journal of Crop and Horticultural Science, Volume 54, Issue 2, June 2026.Cannabis is cultivated for its flowers, which are abundant in volatile terpenes that impact sensory and therapeutic properties. These compounds are therefore targets for enhancement during cultivation. One such strategy is the provision of biostimulants, such as the long‐chain primary alcohol triacontanol (TRIA), which may be sourced from plant waxes ...
Kimber Wise +2 more
wiley +1 more source
Melatonin mitigates hormonal toxicity in cannabis-treated female Wistar rats: involvement of cannabinoid receptor. [PDF]
J Cannabis ResOluwasola A.
europepmc +1 more source
Transcriptome assemblies for two drug‐type cannabis chemotypes by long‐read RNA sequencing
The Plant Genome, Volume 19, Issue 2, June 2026.Abstract Cannabis sativa has undergone over 10,000 years of domestication, resulting in extensive genetic and phenotypic diversity among cultivated chemotypes. Increased medical and recreational use of specialized metabolites accumulating in cannabis glandular trichomes—primarily the cannabinoids ∆9‐tetrahydrocannabinol (THC) and cannabidiol (CBD)—has ...
Oliver Berkowitz +5 more
wiley +1 more source
Insights into cannabinoid receptor 2 (CB2) anterograde trafficking and pharmacological chaperoning. [PDF]
Cell Mol Life SciOyagawa CRM +4 more
europepmc +1 more source
Veterinary Record Open, Volume 13, Issue 1, June 2026.Abstract Background Canine mammary carcinoma (CMC) is characterised by a chronic inflammatory microenvironment resembling human breast cancer; however, the upstream regulatory mechanisms driving this phenotype remain unclear. The endocannabinoid system (ECS) has emerged as a potential modulator of inflammation and tumour biology.
Gianluca Antonio Franco +8 more
wiley +1 more source
Cannabinoid receptor 2 affect the inflammatory response in periodontitis by regulating macrophage M1/M2 polarization. [PDF]
BMC Oral HealthYuan SY, Zhao F, Tao R, Liu B, Liu CY.
europepmc +1 more source
Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks
British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1287-1308, May 2026.The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou +2 more
wiley +1 more source
Type-1 Cannabinoid Receptor Promiscuous Coupling: Computational Insights into Receptor-G Protein Interaction Dynamics. [PDF]
Int J Mol SciBerghella A +7 more
europepmc +1 more source