Results 171 to 180 of about 41,551 (306)

The cannabinoid receptor 2 is an in vivo receptor of bisphenol A during bone formation. [PDF]

open access: yesJ Hazard Mater
Dubuisson MJ   +7 more
europepmc   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

Unlocking Selenium Chemical Space via a Programmable Synthesis Platform Bearing Cannabinoid Receptor Recognition Motifs. [PDF]

open access: yesJ Am Chem Soc
Iyer MR   +7 more
europepmc   +1 more source

In vivo evidence for functional selectivity at the CB1 cannabinoid receptor

open access: yes, 2009
While cannabinoids are generally expected to modulate synaptic communication through depolarisation-induced suppressions of inhibition or excitation (DSI/DSE), we previously reported a CB1 cannabinoid receptor-mediated complex regulation of tyrosine ...
Gordon Research Conferences on Cannabinoid function in the CNS   +1 more
core  

A MassQL‐Based Framework for Rule‐Guided MS/MS Class‐Level Retrieval and Analog Discovery of Cannabinoids

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Cannabinoids comprise a chemically diverse group of meroterpenoids whose extensive isomerism, variable side‐chain length, and frequent oxidative or rearranged derivatives lead to strongly overlapping yet characteristic MS/MS fragmentation patterns. In untargeted LC–MS/MS datasets, this combination of structural diversity and spectral
Julia Maia Galvão de Queiroz   +4 more
wiley   +1 more source

Exploring cannabinoid receptor CB1 autophagy and the obesity phenotype of p62-deficient mice. [PDF]

open access: yesBiochem Biophys Rep
Keller C   +5 more
europepmc   +1 more source

Oromucosal Administration of a Cannabidiol‐Enriched Cannabis sp. Extract for 2 Weeks Moderately Reduces Cold Hyperalgesia in Rats With Neuropathic Pain

open access: yesEuropean Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background Chronic neuropathic pain (CNP) involves complex interactions between resident and peripheral immune cells, as well as modulation of the endocannabinoid system. Cannabis‐based products have emerged as promising therapeutic options, but their effects on immune cells remain unclear.
Raquel Maria Pereira Campos   +5 more
wiley   +1 more source

Neuroprotective Effects of Biosynthetic d‐Calcium Pantothenate and Cyanocobalamin Against MPTP‐Induced Parkinsonism via Microbiota Modulation, Metabolic Homeostasis Restoration, and Endoplasmic Reticulum Stress Inhibition

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Biosynthetic D‐calcium pantothenate and cyanocobalamin alleviate MPTP‐induced Parkinsonism in mice by modulating gut microbiota, restoring metabolic homeostasis, and inhibiting Endoplasmic Reticulum Stress. ABSTRACT Vitamin B5 (VB5) and Vitamin B12 (VB12) are essential micronutrients widely distributed in functional foods, yet their neuroprotective ...
Yaru Chen   +6 more
wiley   +1 more source

Insulin increases expression of cannabinoid receptor 1 by suppressing lysosomal degradation via ERK signaling pathway. [PDF]

open access: yesInt J Med Sci
Liu SY   +12 more
europepmc   +1 more source

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