Results 191 to 200 of about 65,361 (277)

Characterization of binding kinetics and intracellular signaling of new psychoactive substances targeting cannabinoid receptor using transition-based reweighting method. [PDF]

Elife
Dutta S, Shukla D.
europepmc   +1 more source

Review: “The Disappointment Dilemma: Short‐ and Long‐Term Learning From Negative Outcomes”

European Journal of Neuroscience, Volume 63, Issue 9, May 2026.
The habenula routes negative‐outcome signals to VTA, RMTg, and IPN to shape aversive learning and motivation. The lateral habenula encodes acute negative prediction errors to rapidly adapt behavior to threat, fear, and avoidance. The medial habenula integrates repeated stress, drug, and aversive experiences into long‐term negative mood and expectations.
Ines Ibañez‐Tallon, Susanna Molas, Christophe D. Proulx, Joaquin Piriz, Edgar Soria‐Gómez   +4 more
wiley   +1 more source

Opposing Synovial Cannabinoid Receptor Type 2 and Transient Receptor Potential Vanilloid 1 Expression in Painful Osteoarthritis. [PDF]

Cureus
Toups CA, Guillot LG, Redondo K, Jensen S, Klein J, Marrero L.   +5 more
europepmc   +1 more source

Microvascular Effects of Endocannabinoid Signaling in Sepsis: A Mechanistic and Systematic Review

Microcirculation, Volume 33, Issue 4, May 2026.
ABSTRACT Microvascular dysfunction is a central determinant of organ failure in sepsis, reflecting early endothelial activation, increased permeability, and impaired capillary perfusion. Experimental evidence suggests that the endocannabinoid system (ECS) modulates these immunovascular processes, yet mechanistic insights remain dispersed across ...
Emanuel F. Matias, Francisco M. Vila‐Real, Maria A. Vieira‐Coelho   +2 more
wiley   +1 more source

Development of Carborane-Based Benzothiazole Analogues as Cannabinoid Receptor Type 2 (CB₂R) Ligands. [PDF]

ACS Omega
Ueberham L, Kazimir A, Deuther-Conrad W, Hey-Hawkins E.   +3 more
europepmc   +1 more source

Waxy- or Putty-Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity. [PDF]

Drug Test Anal
Timmerman A, Deventer MH, Andrews R, Reid R, Marland V, Edwards D, Pudney CR, Nic Daéid N, Stove CP, Norman C.   +9 more
europepmc   +1 more source

How THC works: Explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1. [PDF]

iScience
Shahbazi-Raz F, Meister D, Mohammadzadeh A, Trant JF.   +3 more
europepmc   +1 more source

Neuroprotective effects of G9a inhibition and cannabinoid receptor activation in Alzheimer's disease through a pharmacological approach. [PDF]

Neurotherapeutics
Bellver-Sanchis A, Ribalta-Vilella M, Lillo J, Ortuño-Sahagún D, Franco R, Pallàs M, Navarro G, Griñán-Ferré C.   +7 more
europepmc   +1 more source

In vitro CB₁ receptor activity of halogenated indazole synthetic cannabinoid receptor agonists. [PDF]

Arch Toxicol
Green H, McKenzie C, Hamra E, Rautio T, Wu X, Juneskog E, Sandblom R, Monti MC, Persson M, Norman C.   +9 more
europepmc   +1 more source

Cannabinoid CB2 receptor [PDF]

Science-Business eXchange, 2008
openaire   +1 more source