Results 211 to 220 of about 41,551 (306)

Dried blood spot analysis in antidoping: Technical challenges, analytical advances, and future perspectives

Bulletin of the Korean Chemical Society, Volume 47, Issue 6, Page 674-688, June 2026.
Dried blood spot (DBS) analysis enables minimally invasive blood collection with strong analyte stability and simplified logistics, supporting anti‐doping applications beyond traditional matrices. Recent advances address hematocrit, volume variability, and matrix effects while expanding coverage to steroid esters, World Anti‐Doping Agency‐listed ...
Jihyun Yoon, Jiyeong Hong, Hanbin Oh, Chi Hwan Lee, Ki Hun Kim   +4 more
wiley   +1 more source

Retraction Note: Crystal structures of agonist-bound human cannabinoid receptor CB₁. [PDF]

Nature
Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, Zhao S, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ.   +19 more
europepmc   +1 more source

Elucidating Immune Cell Mediated Causal Pathways Linking Blood Metabolites to Major Depressive Disorder: A Mediation Mendelian Randomization Analysis

Brain and Behavior, Volume 16, Issue 6, June 2026.
Our integrative Mendelian randomization framework revealed that specific circulating metabolites exert causal effects on major depressive disorder, partly through immune‐cell–mediated pathways. These findings highlight metabolite–immune interactions as potential mechanistic targets for MDD prevention and therapy.
Zhiwei Xu, Yining Zhou, Xuecheng Zhang, Xiaowen Chen, Yajing Li, Jintao Wang, Ting Chang, Zhen Yuan, Hongling Jia   +8 more
wiley   +1 more source

Novel floxed cannabinoid receptor 2 mouse line combines knockout capability with dual fluorescent reporters. [PDF]

Front Pharmacol
Laloli KJ, Rentsch P, Stayte S, Vissel B.   +3 more
europepmc   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, Volume 101, Issue 3, Page 1311-1333, June 2026.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source

Drug Repurposing: Conversion of the Peripherally Restricted HIV Protease Inhibitor Amprenavir to Potent, Selective, and CNS-Penetrant Agonists for the Cannabinoid Receptor 2. [PDF]

J Med Chem
Haymer DH, Duncan RA, Rodriguez AL, Han A, Lindsay RJ, Wijesiri NK, Thompson Gray A, Krishnan S, Qi A, Brown BP, Boutaud O, Engers DW, Jones CK, Niswender CM, Lindsley CW, Bender AM.   +15 more
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

eFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam, Ahmet B. Ortaakarsu, Sohaib Khatib, Mohamed A. Farag, Mansour Sobeh   +4 more
wiley   +1 more source

Cannabigerol Modulates Cannabinoid Receptor Type 2 Expression in the Spinal Dorsal Horn and Attenuates Neuropathic Pain Models. [PDF]

Pharmaceuticals (Basel)
Rezende B, Fernandes GG, de Simas Gonçalves VM, Nascimento GG, Marques KL, de Oliveira BCCA, Dos Santos YB, de Andrade MEB, Calumbi KS, Maia EP, Trefilio LM, Antunes F, Fontes-Dantas FL, Montes GC.   +13 more
europepmc   +1 more source

Nutritional Composition, Therapeutic Benefits, and Functional Food Potential of Coleus amboinicus: A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Coleus amboinicus is a nutrient‐rich herb containing vitamins (A‐, C‐, B‐complex), minerals (Ca, Mg, Fe, K), dietary fiber, and potent bioactives such as rosmarinic acid, quercetin, thymol, and carvacrol. These compounds contribute to antioxidant, anti‐inflammatory, antimicrobial, prebiotic, and cardioprotective benefits.
Shani Upadhyay, Rakesh Verma, Shikha Gupta   +2 more
wiley   +1 more source

Activity of protein kinase C controls the efficacy of cannabinoid receptor type 1 in the medial prefrontal cortex after neuropathic pain. [PDF]

J Neurophysiol
Chao D, Liu Y, Cheng T, Hogan QH, Pan B.
europepmc   +1 more source