CBD oil exhibits neuroprotective effects in Parkinson's disease models by inhibiting NLRP3 inflammasome activation. It preserves dopamine levels and reduces α‐synuclein accumulation, suggesting its potential as a therapeutic strategy against neuroinflammation and neurodegeneration.
Göksun Demirel +7 more
wiley +1 more source
Characterization of binding kinetics and intracellular signaling of new psychoactive substances targeting cannabinoid receptor using transition-based reweighting method. [PDF]
Dutta S, Shukla D.
europepmc +1 more source
ABSTRACT Common beans (Phaseolus vulgaris L.) are essential raw material for the canning industry. This article reviews recent advances in assessing canning quality and the integration of artificial intelligence (AI) into breeding methodologies aimed at developing genotypes with superior yield and canning‐quality traits.
Arash Ghaitaranpour +2 more
wiley +1 more source
Opposing Synovial Cannabinoid Receptor Type 2 and Transient Receptor Potential Vanilloid 1 Expression in Painful Osteoarthritis. [PDF]
Toups CA +5 more
europepmc +1 more source
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Cannabis is cultivated for its flowers, which are abundant in volatile terpenes that impact sensory and therapeutic properties. These compounds are therefore targets for enhancement during cultivation. One such strategy is the provision of biostimulants, such as the long‐chain primary alcohol triacontanol (TRIA), which may be sourced from plant waxes ...
Kimber Wise +2 more
wiley +1 more source
Waxy- or Putty-Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity. [PDF]
Timmerman A +9 more
europepmc +1 more source
ABSTRACT Background The applicability of spontaneous reporting systems such as the US Food and Drug Administration Adverse Event Reporting System (FAERS) to detect cannabis‐related safety signals remains unclear due to the potential for discrepant reporting patterns between pharmaceutical and non‐pharmaceutical cannabis‐derived products (CDPs ...
Priscilla O. M. V. Lopes +2 more
wiley +1 more source
Development of Carborane-Based Benzothiazole Analogues as Cannabinoid Receptor Type 2 (CB<sub>2</sub>R) Ligands. [PDF]
Ueberham L +3 more
europepmc +1 more source
How THC works: Explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1. [PDF]
Shahbazi-Raz F +3 more
europepmc +1 more source

