Results 201 to 210 of about 41,551 (306)

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei   +7 more
wiley   +1 more source

Synthesis and Pharmacological Characterization of a Novel Cannabinoid Receptor 1 Antagonist. [PDF]

open access: yesACS Omega
Bengoetxea de Tena I   +13 more
europepmc   +1 more source

Effect of plant population on crop growth, floral biomass, and cannabinoid yield in field‐grown hemp

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 2, June 2026.
Abstract Hemp (Cannabis sativa L.) was recently re‐legalized in the United States and cultivated for various purposes, including floral cannabidiol (CBD), grain, and fiber. Due to prohibition of hemp for a century, research supporting production guidelines, including plant density effects on CBD production, remains limited.
Richard J. Roseberg   +2 more
wiley   +1 more source

Crystal structures of agonist-bound human cannabinoid receptor CB<sub>1</sub>. [PDF]

open access: yesNature
Hua T   +18 more
europepmc   +1 more source

Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression

open access: yesArchiv der Pharmazie, Volume 359, Issue 6, June 2026.
Ion channel remodelling induced by neuroinflammation in multiple sclerosis alters neuronal excitability and immune signalling, creating shared molecular pathways that link multiple sclerosis pathology to depression and reveal novel pharmacological targets.
Nicole Rychlik   +4 more
wiley   +1 more source

Low‐dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug–drug interaction study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1595-1606, June 2026.
Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko   +9 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Naringin Alleviates Autistic-Like Behaviors in BTBR Mice Through Cannabinoid Receptor Type 1-Mediated Restoration of Hippocampal Neurogenesis. [PDF]

open access: yesCNS Neurosci Ther
Liu Y   +12 more
europepmc   +1 more source

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