Results 11 to 20 of about 2,668,334 (282)
Neural Plasticity, 2015 Neurocognitive effects of cannabinoids have been extensively studied with a focus on CB1 cannabinoid receptors because CB1 receptors have been considered the major cannabinoid receptor in the nervous system. However, recent discoveries of CB2 cannabinoid
Yong Li, Jimok Kim
semanticscholar +2 more sources
Extracellular glutamate is not modulated by cannabinoid receptor activity. [PDF]
Sci RepCannabinoid receptor activation has been proposed to trigger glutamate release from astrocytes located in cortical layer 2/3. Here, we measure the basal concentration of extracellular glutamate in layer 2/3 of mouse somatosensory cortex and find it to be
Chiu DN, Carter BC.
europepmc +2 more sources
Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum
Animals, 2021 An important piece of evidence has shown that molecules acting on cannabinoid receptors influence gastrointestinal motility and induce beneficial effects on gastrointestinal inflammation and visceral pain.
Andrea Toschi +6 more
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Increased expression of cannabinoid CB₁ receptors in Achilles tendinosis. [PDF]
PLoS ONE, 2011 BACKGROUND: The endogenous cannabinoid system is involved in the control of pain. However, little is known as to the integrity of the cannabinoid system in human pain syndromes.
Emmelie Björklund +3 more
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Molecular Insights into Epigenetics and Cannabinoid Receptors
Biomolecules, 2022 The actions of cannabis are mediated by G protein-coupled receptors that are part of an endogenous cannabinoid system (ECS). ECS consists of the naturally occurring ligands N-arachidonylethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG), their ...
Balapal S. Basavarajappa +1 more
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Receptor mechanism of infarct-limiting effect of adaptation to normobaric hypoxia
Бюллетень сибирской медицины, 2021 The aim of the study was to investigate the involvement of bradykinin, cannabinoid and vanilloid (TRPV1 channel) receptors in the implementation of the infarct-limiting effect of chronic normobaric hypoxia (CNH).Materials and methods.
N. V. Naryzhnaya +3 more
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Roles of the Cannabinoid System in the Basal Ganglia in Parkinson’s Disease
Frontiers in Cellular Neuroscience, 2022 Parkinson’s disease (PD) is a neurodegenerative disease usually caused by neuroinflammation, oxidative stress and other etiologies. Recent studies have found that the cannabinoid system present in the basal ganglia has a strong influence on the ...
Mengya Wang, Huayuan Liu, Zegang Ma
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Frontiers in Pharmacology, 2023 Sevoflurane is widely used for maternal anesthesia during pregnancy. Sevoflurane exposure of rats at mid-gestation can cause abnormal development of the central nervous system in their offspring.
Yuxiao Wan +3 more
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Pharmacology Research & Perspectives, 2022 Sexual dimorphisms are observed in cannabinoid pharmacology. It is widely reported that female animals are more sensitive to the cataleptic, hypothermic, antinociceptive, and anti‐locomotive effects of cannabinoid receptor agonists such as CP55,940 ...
Hye Ji J. Kim +5 more
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In Vitro Signaling Properties of Cannabinoid and Orexin Receptors: How Orexin Receptors Influence Cannabinoid Receptor-Mediated Signaling. [PDF]
Pharmacol Res PerspectThe co‐expression of different types of G protein‐coupled receptors (GPCRs) in the same cells can have implications for receptor signaling and receptor cross‐talk, potentially altering the apparent potency or efficacy of ligands targeting each receptor ...
Mohamed KA, Laprairie RB.
europepmc +2 more sources