Results 21 to 30 of about 41,551 (306)
Cannabinoids and Cannabinoid Receptors: The Story so Far [PDF]
iScience, 2020 Like most modern molecular biology and natural product chemistry, understanding cannabinoid pharmacology centers around molecular interactions, in this case, between the cannabinoids and their putative targets, the G-protein coupled receptors (GPCRs) cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2).
Fred Shahbazi +3 more
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Frontiers in Pharmacology, 2023 Sevoflurane is widely used for maternal anesthesia during pregnancy. Sevoflurane exposure of rats at mid-gestation can cause abnormal development of the central nervous system in their offspring.
Yuxiao Wan +3 more
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Pharmacology Research & Perspectives, 2022 Sexual dimorphisms are observed in cannabinoid pharmacology. It is widely reported that female animals are more sensitive to the cataleptic, hypothermic, antinociceptive, and anti‐locomotive effects of cannabinoid receptor agonists such as CP55,940 ...
Hye Ji J. Kim +5 more
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Cannabinoid receptors in invertebrates [PDF]
Journal of Evolutionary Biology, 2006 Abstract Two cannabinoid receptors, CB1 and CB2, are expressed in mammals, birds, reptiles, and fish. The presence of cannabinoid receptors in invertebrates has been controversial, due to conflicting evidence. We conducted a systematic review of the literature, using expanded search parameters. Evidence presented in the literature varied
J M, McPartland +4 more
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Frontiers in Neuroscience, 2021 The endocannabinoid and orexin neuromodulatory systems serve key roles in many of the same biological functions such as sleep, appetite, pain processing, and emotional behaviors related to reward.
Hye Ji J. Kim +7 more
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Differential β-arrestin2 requirements for constitutive and agonist-induced internalization of the CB1 cannabinoid receptor [PDF]
, 2013 CB1 cannabinoid receptor (CB1R) undergoes both constitutive and agonist-induced internalization, but the underlying mechanisms of these processes and the role of beta-arrestins in the regulation of CB1R function are not completely understood.
Boros, Eszter +7 more
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Influence of cannabinoid receptor GPR55 upon salivation of rat submandibular salivary gland
Біологічні студії, 2013 This paper is devoted to elucidation of functionally active cannabinoid receptor GPR55 in submandibular salivary gland cells of rats by introducing a specific agonist lysophosphatidylinositol.
S. Y. Korchynska +2 more
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Cells, 2021 The endocannabinoid (eCB) system has been found in all visual parts of the central ner-vous system and plays a role in the processing of visual information in many species, including monkeys and humans. Using anatomical methods, cannabinoid receptors are
Joseph Bouskila +4 more
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The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease. [PDF]
, 2010 Recent evidence suggests a crucial role of the endocannabinoid system, including the cannabinoid 1 receptor (CNR1), in intestinal inflammation. We therefore investigated the influence of the CNR1 1359 G/A (p.Thr453Thr; rs1049353) single nucleotide ...
Brand, Stephan +23 more
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Frontiers in Veterinary Science, 2019 Growing evidence indicates cannabinoid receptors as potential therapeutic targets for chronic pain. Consequently, there is an increasing interest in developing cannabinoid receptor agonists for treating human and veterinary pain. To better understand the
Roberto Chiocchetti +9 more
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