Results 231 to 240 of about 2,668,334 (282)
Some of the next articles are maybe not open access.
Cannabinoid receptors in atherosclerosis
Current Opinion in Lipidology, 2006Recent findings suggesting that cannabinoid receptors are potential targets for the treatment of atherosclerosis are reviewed.Cannabinoids, such as Delta9-tetrahydrocannabinol, the major psychoactive compound of marijuana, their synthetic analogs and endogenous cannabinoid ligands, produce their biological effects by interacting with specific receptors.
Sabine, Steffens, Francois, Mach
openaire +2 more sources
Canonical Cannabinoid Receptors
This chapter will review the basic pharmacology of the canonical cannabinoid receptors. The endocannabinoid system is a complex signalling network involved in a wide range of physiological processes, including pain modulation, appetite regulation, and synaptic plasticity.Beth, Ehrlich +3 more
openaire +2 more sources
Pharmacology of Cannabinoid Receptors
Annual Review of Pharmacology and Toxicology, 1995Two subtypes of cannabinoid receptors, CB1 and CB2, have been described to date, although future investigations may elucidate other receptors. The actions of cannabimimetic agents via CB1 receptors in brain are mediated by GI/O to inhibit adenylate cyclase and Ca2+ channels. Little is known about signal transduction mechanisms utilized by CB2 receptors.
openaire +2 more sources
Cannabinoid receptors and pain
Progress in Neurobiology, 2001Mammalian tissues contain at least two types of cannabinoid receptor, CB(1) and CB(2), both coupled to G proteins. CB(1) receptors are expressed mainly by neurones of the central and peripheral nervous system whereas CB(2) receptors occur centrally and peripherally in certain non-neuronal tissues, particularly in immune cells.
openaire +2 more sources
SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.
Journal of Pharmacology and Experimental Therapeutics, 1998Based on both binding and functional data, this study introduces SR 144528 as the first, highly potent, selective and orally active antagonist for the CB2 receptor.
M. Rinaldi-Carmona +13 more
semanticscholar +1 more source
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
Nature, 1990L. Matsuda +4 more
semanticscholar +1 more source
Isolation and structure of a brain constituent that binds to the cannabinoid receptor.
Science, 1992W. Devane +9 more
semanticscholar +1 more source
C&EN Global Enterprise, 2016
Two research groups have independently elucidated the first crystal structures of the cannabinoid receptor CB1, a cell-membrane protein involved in a host of appetite, pain-sensation, memory, and o...
openaire +1 more source
Two research groups have independently elucidated the first crystal structures of the cannabinoid receptor CB1, a cell-membrane protein involved in a host of appetite, pain-sensation, memory, and o...
openaire +1 more source