Results 151 to 160 of about 1,296,096 (233)

Discovery of new CB2 cannabinoid receptor full agonists

, 2018
Cannabinoid CB2 receptor agonists have gained attention as potential therapeutic targets in the management of numerous diseases. Selectivity towards this receptor subtype is necessary to avoid the characteristic central side effects, mediated by CB1 ...
Ruggiero, Emanuela
core  

In vitro CB₁ receptor activity of halogenated indazole synthetic cannabinoid receptor agonists. [PDF]

Arch Toxicol
Green H, McKenzie C, Hamra E, Rautio T, Wu X, Juneskog E, Sandblom R, Monti MC, Persson M, Norman C.   +9 more
europepmc   +1 more source

CB₁ cannabinoid receptor agonists induce acute respiratory depression in awake mice. [PDF]

Pharmacol Res
Watkins J, Aradi P, Hahn R, Makriyannis A, Mackie K, Katona I, Hohmann AG.   +6 more
europepmc   +1 more source

Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice. [PDF]

Drug Alcohol Depend
James JC, Thrush JR, Yusufali TM, Shaw HE, Avram M, Moran JH, Fantegrossi WE.   +6 more
europepmc   +1 more source

The resurgence of synthetic cannabinoid receptor agonists as adulterants in the Era of Cannabis legalization: Lessons from prior epidemics and clinical implications. [PDF]

Neurosci Biobehav Rev
Jones AT, Marwan Abu Taha A, Miller GP.
europepmc   +1 more source

4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as functional selective ligands at the hCB2 cannabinoid receptor

, 2012
Cannabinoid compounds (both synthetic and endogenous) exert their effects through at least two different G protein-coupled receptors, the CB1 and CB2 cannabinoid receptors.
Stern, Eric, Muccioli, Giulio, 22nd annual symposium of the international cannabinoid research society, Bosier, Barbara, Lambert, Didier   +4 more
core  

Structure-metabolism relationships of 4-pentenyl synthetic cannabinoid receptor agonists using in vitro human hepatocyte incubations and high-resolution mass spectrometry. [PDF]

Arch Toxicol
Baginski SR, Lindbom K, Valencia Crespo B, Bessa G, Rautio T, Wu X, Dahlén J, Nisbet LA, McKenzie C, Gréen H.   +9 more
europepmc   +1 more source

Post-Mortem Toxicology: A Systematic Review of Death Cases Involving Synthetic Cannabinoid Receptor Agonists. [PDF]

Front Psychiatry, 2020
Giorgetti A, Busardò FP, Tittarelli R, Auwärter V, Giorgetti R.   +4 more
europepmc   +1 more source

Synthetic cannabinoid receptor agonists containing silicon: exploring the metabolic pathways of ADMB- and Cumyl-3TMS-PrINACA in human urine specimens and post mortem material compared to in vitro and in silico data. [PDF]

Arch Toxicol
Zschiesche A, Carlier J, Pietsch J, Scheu M, Seibt J, Busardò FP, Auwärter V, Huppertz LM.   +7 more
europepmc   +1 more source

Pharmacological evaluation of new generation OXIZID synthetic cannabinoid receptor agonists. [PDF]

Eur J Pharmacol
Patel M, Zheng X, Akinfiresoye LR, Prioleau C, Walker TD, Glass M, Marusich JA.   +6 more
europepmc   +1 more source