Results 91 to 100 of about 56,314 (199)

Cortical and Striatal Circuits in Huntington's Disease

, 2020
Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms.
Blumenstock, S., Dudanova, I.
core   +1 more source

The synthetic cannabinoids menace: a review of health risks and toxicity

European Journal of Medical Research
Synthetic cannabinoids (SCs) are chemically classified as psychoactive substances that target the endocannabinoid system in many body organs. SCs can initiate pathophysiological changes in many tissues which can be severe enough to damage the normal ...
Ayman Alzu’bi, Fatimah Almahasneh, Ramada Khasawneh, Ejlal Abu-El-Rub, Worood Bani Baker, Raed M. Al-Zoubi   +5 more
doaj   +1 more source

Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. [PDF]

, 2018
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe and dose-limiting side effect of cancer treatment that affects millions of cancer survivors throughout the world and current treatment options are extremely limited by their side effects ...
Mackie, Ken, Marty, Vincent N, Mulpuri, Yatendra, Munier, Joseph J, Schmidt, Brian L, Seltzman, Herbert H, Spigelman, Igor   +6 more
core   +1 more source

The evolution of cannabinoid receptors in cancer. [PDF]

WIREs Mech Dis, 2023
Pennant NM, Hinton CV.
europepmc   +1 more source

The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data

Brazilian Journal of Psychiatry
Objective: Schizophrenia is a multifactorial disorder. It is known that a combination of extensive multiple common alleles may be involved in its etiology, each contributing with a small to moderate effect, and, possibly, some rare alleles with a much ...
Eduardo S. Gouvêa, Airton F. Santos Filho, Vanessa K. Ota, Vinicius Mrad, Ary Gadelha, Rodrigo A. Bressan, Quirino Cordeiro, Sintia I. Belangero   +7 more
doaj   +1 more source

Update on the Role of Cannabinoid Receptors after Ischemic Stroke

Mediators of Inflammation, 2012
Cannabinoids are considered as key mediators in the pathophysiology of inflammatory diseases, including atherosclerosis. In particular, they have been shown to reduce the ischemic injury after acute cardiovascular events, such as acute myocardial ...
Luciano S. A. Capettini, Silvia Q. Savergnini, Rafaela F. da Silva, Nikos Stergiopulos, Robson A. S. Santos, François Mach, Fabrizio Montecucco   +6 more
doaj   +1 more source

Expression of Cannabinoid Receptors in the Trigeminal Ganglion of the Horse. [PDF]

Int J Mol Sci, 2023
Zamith Cunha R, Semprini A, Salamanca G, Gobbo F, Morini M, Pickles KJ, Roberts V, Chiocchetti R.   +7 more
europepmc   +1 more source

The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer's Disease. [PDF]

J Clin Med, 2023
Ferrisi R, Gado F, Ricardi C, Polini B, Manera C, Chiellini G.   +5 more
europepmc   +1 more source

The development and therapeutic potential of classical and next-generation cannabinoid ligands

Pharmacological Research
The endogenous cannabinoid system (ECS) is a complex network that plays a crucial role in various physiological processes, and its modulation through cannabinoid ligands has garnered significant interest in pharmacological research. Cannabinoid receptors,
Verónica Muñoz-Canales, Bellinda Benhamú, Mar Martín-Fontecha, Henar Vázquez-Villa, Silvia Ortega-Gutiérrez   +4 more
doaj   +1 more source

Alcohol induced behavioral and immune perturbations are attenuated by activation of CB2 cannabinoid receptors. [PDF]

Adv Drug Alcohol Res, 2023
Roberts A, Christian M, Dilone LN, Nelson N, Endrino MJ, Kneebone A, Embaby S, Fernandez J, Liu QR, Onaivi ES, Kibret BG.   +10 more
europepmc   +1 more source