Results 131 to 140 of about 28,905 (252)

Global Prevalence of Self‐Reported Alarm Features in the General Population and Among Individuals With Disorders of Gut–Brain Interaction—Results From the Rome Foundation Global Epidemiology Study

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Background Data on the global prevalence of alarm features in the general population and among individuals with disorders of gut–brain interaction (DGBI) are limited. Methods We analysed data from the Rome Foundation Global Epidemiology Study to estimate the prevalence of fourteen self‐reported alarm features in the global population and among
Jessica Sjölund, Jóhann P. Hreinsson, Brian E. Lacy, Hans Törnblom, Shrikant I. Bangdiwala, Olafur S. Palsson, Ami D. Sperber, Magnus Simren   +7 more
wiley   +1 more source

Altered Network Function in Hippocampus After Sub-Chronic Activation of Cannabinoid Receptors in Early Adolescence. [PDF]

Int J Mol Sci
Rehn J, Admeus L, Kocsis B.
europepmc   +1 more source

Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina. [PDF]

Int J Mol Sci, 2023
Papadogkonaki S, Spyridakos D, Lapokonstantaki E, Chaniotakis N, Makriyannis A, Malamas MS, Thermos K.   +6 more
europepmc   +1 more source

Prevalence and Burden of Fatigue Across Disorders of Gut–Brain Interaction: Results From the Rome Foundation Global Epidemiology Study

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 5, Page 659-674, September 2026.
Fatigue is common and burdensome in disorders of gut‐brain interaction and increases with diagnostic overlap. In this global population‐based study, fatigue was associated with female sex, age, BMI, sleep disturbance, higher anxiety and depression scores, greater somatic symptom burden, lower psychological well‐being, antidepressant use, and greater ...
Fleur Veldman, Francesco Innocenti, Imran Aziz, Asma Fikree, Shrikant I. Bangdiwala, Olafur Palsson, Ami D. Sperber, Daniel Keszthelyi   +7 more
wiley   +1 more source

Evaluation of Anti-Inflammatory Effects of <i>Cannabis sativa</i> Extracts via Possible Modulation of mRNA Levels of Inflammatory Cytokines and Cannabinoid Receptors. [PDF]

Nutrients
Bartkowiak-Wieczorek J, Kujawski R, Szulc M, Czora-Poczwardowska K, Szymczak J, Gierszewska J, Miotk M, Mikołajczak P, Mądry E, Grzelak T.   +9 more
europepmc   +1 more source

The Leu/Val^6.51 Side Chain of Cannabinoid Receptors Regulates the Binding Mode of the Alkyl Chain of Δ⁹-Tetrahydrocannabinol. [PDF]

J Chem Inf Model, 2023
Llinas Del Torrent C, Raïch I, Gonzalez A, Casajuana-Martin N, Lillo J, Rebassa JB, Ferreiro-Vera C, Sánchez de Medina V, Franco R, Navarro G, Pardo L.   +10 more
europepmc   +1 more source

Cannabinoid and adenosine A2A receptor crosstalk regulates postnatal and adult hippocampal neurogenesis

British Journal of Pharmacology, Volume 183, Issue 18, Page 5440-5457, September 2026.
Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues, Adam Armada‐Moreira, Laura Gómez‐Acero, Filipa F. Ribeiro, Francisco M. Mouro, Ana M. Sebastião, Francisco Ciruela, Ester Aso, Sara Xapelli   +8 more
wiley   +1 more source

Therapeutic Potential of Cannabinoid Receptors Type 1 and 2-Novel Insights for Enhancing the Chance of Clinical Success. [PDF]

Pharmaceuticals (Basel)
Grether U.
europepmc   +1 more source

The endocannabinoid system's involvement in motor development relies on cannabinoid receptors, TRP channels, and Sonic Hedgehog signaling. [PDF]

Physiol Rep, 2023
Khara LS, Ali DW.
europepmc   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, Volume 183, Issue 18, Page 5458-5475, September 2026.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source