Endocannabinoid system and anticancer properties of cannabinoids [PDF]
, 2016 Cannabinoids impact human body by binding to cannabinoids receptors (CB1 and CB2). The two main phytocannabinoids are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD).
Nowak, Agnieszka +3 more
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Modulation of the Endocannabinoid System as a Potential Anticancer Strategy
Frontiers in Pharmacology, 2019 Currently, the involvement of the endocannabinoid system in cancer development and possible options for a cancer-regressive effect of cannabinoids are controversially discussed.
Robert Ramer +2 more
doaj +1 more source
On the G-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation [PDF]
, 2013 The modulatory role of allosteric receptor-receptor interactions in the pain pathways of the Central Nervous System and the peripheral nociceptors has become of increasing interest.
Agnati, Luigi F +6 more
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Cannabinoids and Innate Immunity: Taking a Toll on Neuroinflammation
The Scientific World Journal, 2011 The biologically active components of cannabis have therapeutic potential in neuroinflammatory disorders due to their anti-inflammatory propensity. Cannabinoids influence immune function in both the peripheral and the central nervous system (CNS), and ...
Eric J. Downer
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Cannabinoid Ligands Targeting TRP Channels
Frontiers in Molecular Neuroscience, 2019 Transient receptor potential (TRP) channels are a group of membrane proteins involved in the transduction of a plethora of chemical and physical stimuli.
Chanté Muller +2 more
doaj +1 more source
The Medicalization of Cannabis [PDF]
, 2010 Annotated and edited transcript of a Witness Seminar held on 24 March 2009. Introduction by Professor Leslie Iversen.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2010.©The Trustee of the Wellcome Trust, London, 2010 ...
Crowther, SM, Reynolds, LA, Tansey, EM
core
Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]
, 2016 Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
core +4 more sources
The Endocannabinoid System in the Retina: From Physiology to Practical and Therapeutic Applications
Neural Plasticity, 2016 Cannabis is one of the most prevalent drugs used in industrialized countries. The main effects of Cannabis are mediated by two major exogenous cannabinoids: ∆9-tetrahydroxycannabinol and cannabidiol.
Thomas Schwitzer +4 more
doaj +1 more source
Neurobiology of cannabinoid receptor signaling
Dialogues in Clinical Neuroscience, 2020 The endocannabinoid system (ECS) is a highly versatile signaling system within the nervous system. Despite its widespread localization, its functions within the context of distinct neural processes are very well discernable and specific. This is remarkable, and the question remains as to how such specificity is achieved.
openaire +3 more sources
Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding [PDF]
, 2010 Peer reviewedPublisher ...
Barabas, Klaudia +9 more
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