Results 181 to 190 of about 64,716 (311)

Full‐Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164) Improves Symptoms of Rett Syndrome: An Open‐Label Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating, Y. Ogru, T. G. Duthy, L. Douglas, K. Lichkus, E. Isikgel, M. C. Fahey, C. Ellaway   +7 more
wiley   +1 more source

Cannabinoids in Alzheimer's disease: animal-human evidence and clinical pharmacology challenges. [PDF]

Front Behav Neurosci
Komedera M, Wojda U, Kiryk A.
europepmc   +1 more source

Assessment of Cannabidiol Supplements Use in Small Animals Practice in Portugal

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study aimed to assess the current use of cannabidiol supplements (CBDS) by Portuguese small animal veterinary practitioners. An anonymous online survey questioning the frequency of CBDS use, purpose of use and the perceived outcome was developed using Microsoft Forms, and targeted veterinarians currently working in small animal clinics in
Maria Inês Santos, Ana Luísa Lourenço
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Cannabinoid-Driven Rewiring of GPCR and Ion Channel Signaling in Lung Cancer. [PDF]

Biomedicines
Heriyanto DS, Nurkolis F, Choi J, Park S, Choi M, Tjandrawinata RR, Rani A, Park MN, Kwak MJ, Shim BS, Kim B.   +10 more
europepmc   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Industrial and Therapeutic Applications of Hemp: A Review. [PDF]

Molecules
Chiririwa H.
europepmc   +1 more source

Delta‐9‐Tetrahydrocannabinol (THC) Before Bedtime: Feasibility and Mechanistic Pilot Study on Sleep and Cardiac Autonomic Activity

Journal of Sleep Research, EarlyView.
ABSTRACT Disordered sleep is a common reason individuals report using cannabis, yet the physiological effects of Δ9‐tetrahydrocannabinol (Δ9‐THC) on sleep and autonomic regulation remain incompletely understood. Early studies reported acute sleep‐promoting effects of Δ9‐THC, but chronic use has been associated with disrupted sleep and possible ...
Joshua E. Gonzalez, Alicia V. Stewart, Jacquelin L. Ellison, Omar H. Ordaz, LaTroy D. Robinson, Noal A. Clemons, Jonathan S. Emens, Sean P. M. Rice, Steven A. Shea, Nicole P. Bowles   +9 more
wiley   +1 more source

Nutritive Value and Cannabinoid Potency of Diverse Hemp (<i>Cannabis sativa</i> L.) Varieties Grown under Different Light Conditions and Harvested across Multiple Time Points as a Possible Feed Source for Livestock. [PDF]

J Agric Food Chem
Duringer JM, Saindon A, Irawan A, Ates S, Brownstein KJ, Gude KM, Ringo C, Kinney CA, Berhow M, Steiner J.   +9 more
europepmc   +1 more source

Straddling “The Gulf Between Medicine and Law”: Medico‐legal addiction and Japanese psychiatry

Medical Anthropology Quarterly, EarlyView.
Abstract Increasing punitive drug regulations in Japan amplify longstanding tensions within psychiatric practice, pushing psychiatrists to balance clinical obligations with complex socio‐legal demands. This article analyzes how psychiatrists specializing in illicit substance use disorders to navigate escalating criminalization by developing diagnostic ...
Selim Gokce Atici
wiley   +1 more source