Results 191 to 200 of about 47,203 (289)

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

SGIP1 limits cannabinoid receptor signalling in spinal nociceptive synapses and modulates analgesia during neuroinflammation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend SGIP1 constrains presynaptic cannabinoid signalling in the spinal dorsal horn and limits cannabinoid analgesia after inflammation. In vivo (both sexes), SGIP1 KO mice showed a higher baseline heat threshold but unchanged mechanical sensitivity.
Denisa Dresslerova   +7 more
wiley   +1 more source

Hemp Cultivation and Crop Diversification: Implications for Ecosystem Services in Kentucky

open access: yesApplied Economic Perspectives and Policy, Volume 48, Issue 5, Page 1367-1382, December 2026.
ABSTRACT This study examines the ecosystem benefits of expanding hemp cultivation by assessing its impact on crop diversity. Using scenario‐based simulations and fixed‐effect panel regressions with county‐level data in Kentucky, we find that increased hemp acreage tends to enhance crop diversity, improving water quality and bird diversity.
Yunsun Park   +4 more
wiley   +1 more source

Short‐term agronomic consequences of industrial hemp incorporation into traditional corn–soybean rotations

open access: yesAgrosystems, Geosciences &Environment, Volume 9, Issue 4, December 2026.
Abstract Kentucky producers have sought to add industrial hemp (Cannabis sativa L.) for grain, fiber, and/or floral material to their cropping systems since hemp's legalization in the 2018 Farm Bill. This study sought to quantify hemp's impact on ecosystem services provisioned by the traditional corn (Zea mays L.)–soybean (Glycine max (L.) Merr ...
Rebecca K. McGrail   +5 more
wiley   +1 more source

Perspectives in biomedicine: Superfoods and antioxidant power classification

open access: yesThe Canadian Journal of Chemical Engineering, Volume 104, Issue 12, Page 6393-6402, December 2026.
Abstract The market value of natural food antioxidants will double to 8 billion USD by 2033, driven by a global consumer demand for ‘clean label’ products and proactive wellness solutions. However, the industrial application and health labelling (commercial brands) of these compounds remain severely constrained by inconsistent analytical methods.
Domenico Fuoco, Gregory S. Patience
wiley   +1 more source

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