Results 91 to 100 of about 337,650 (402)

Population pharmacokinetic modelling revealed large variability in oromucosal absorption of Δ9‐tetrahydrocannabinol in older patients with poor appetite

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Cannabis‐based medicines are gaining interest and being explored for new therapeutic indications, many of which commonly affect older medical patients. As most previous studies of the population pharmacokinetics of cannabinoids have been performed in healthy adults, this study aimed to investigate the population pharmacokinetics of Δ9 ...
Ida Klitzing Storgaard   +12 more
wiley   +1 more source

Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects

open access: yesFrontiers in Pharmacology, 2020
This review aims to present completed clinical trial data surrounding the medicinal benefits and potential side effects of the increasingly popular cannabidiol (CBD)-based drug products, specifically Epidiolex.
Christopher S. Pauli   +4 more
doaj   +1 more source

Assessment of clinical outcomes in patients with fibromyalgia: Analysis from the UK Medical Cannabis Registry

open access: yesBrain and Behavior, 2023
Introduction : There are limited therapeutic options for individuals with fibromyalgia. The aim of this study is to analyze changes in health‐related quality of life and incidence of adverse events of those prescribed cannabis‐based medicinal products ...
Claire Wang   +10 more
doaj   +1 more source

Substance Use and Depression Symptomatology: Measurement Invariance of the Beck Depression Inventory (BDI-II) among Non-Users and Frequent-Users of Alcohol, Nicotine and Cannabis [PDF]

open access: yes, 2016
Depression is a highly heterogeneous condition, and identifying how symptoms present in various groups may greatly increase our understanding of its etiology.
Moore, Ashlee A.   +3 more
core   +4 more sources

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro   +5 more
wiley   +1 more source

UK Medical Cannabis Registry: An analysis of clinical outcomes of medicinal cannabis therapy for attention‐deficit/hyperactivity disorder

open access: yesNeuropsychopharmacology Reports, 2023
Aim This study aims to analyze the health‐related quality of life (HRQoL) and safety outcomes in attention‐deficit/hyperactivity disorder (ADHD) patients treated with cannabis‐based medicinal products (CBMPs). Methods Patients were identified from the UK
Pim Ittiphakorn   +5 more
doaj   +1 more source

An examination into the possibility of the UK being a predominantly cannabis producing nation and a methodology of cultivation techniques [PDF]

open access: yes, 2016
Previously, the UK has been known to heavily import cannabis from producer countries, more recently vast quantities of cannabis farms are being discovered throughout the nation.
O'Hagan, A, Parker, A
core  

Prospective memory functioning among ecstasy/polydrug users: evidence from the Cambridge Prospective Memory Test (CAMPROMPT) [PDF]

open access: yes, 2011
Rationale: Prospective memory (PM) deficits in recreational drug users have been documented in recent years. However, the assessment of PM has largely been restricted to self-reported measures that fail to capture the distinction between event-based and
A Costa   +52 more
core   +1 more source

Changes in delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) concentrations in cannabis over time: systematic review and meta-analysis.

open access: yesAddiction, 2020
BACKGROUND AND AIMS Cannabis products with high delta-9-tetrahydrocannabinol (THC) concentrations carry an increased risk of addiction and mental health disorders, while it has been suggested that cannabidiol (CBD) may moderate the effects of THC.
T. Freeman   +6 more
semanticscholar   +1 more source

Drug poisonings following bariatric surgery: Case series report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari   +3 more
wiley   +1 more source

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