Results 71 to 80 of about 82,568 (267)

Multivariate Robustness Modeling of Cannabidiol and Δ⁹-Tetrahydrocannabinol Quantification Using Two-Level Full Factorial Design

Scientia Pharmaceutica
The present study aimed to establish a robustness modeling framework for the determination of cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) in cannabis extract using a multivariate approach.
Athip Maha, Thanapat Songsak, Surang Leelawat, Chaowalit Monton   +3 more
doaj   +1 more source

Estimating Illicit Stimulant Drug Consumption in Luxembourg Using Wastewater‐Based Epidemiology

Drug Testing and Analysis, EarlyView.
Wastewater‐based epidemiology provided nationwide estimates of illicit stimulant consumption in Luxembourg, revealing higher urban use, weekend increases in cocaine and MDMA, and cocaine as the dominant stimulant. The approach offers an objective complement to conventional drug surveillance for informing public health and policy.
Nadine Berndt, Luca Wiltgen, Nicolas Villani, Georges Dahm, Karin Roschel, Serge Schneider   +5 more
wiley   +1 more source

Changes in patterns of use and perceptions of cannabis among students in Canada: A decade of data from the Canadian Student Alcohol and Drugs Survey

Drug and Alcohol Dependence Reports
Introduction: The Canadian Student Alcohol and Drugs Survey is a biennial, repeat cross-sectional survey of grade 7–12 students in the Canadian provinces. This study examined cannabis-related behaviours at five timepoints before and after legalization of
Samantha Goodman, Sebastian A. Srugo, Emilia Krzeminska, Hanan Abramovici   +3 more
doaj   +1 more source

Population‐Stratified Distributions of Post‐Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual Interpretation

Drug Testing and Analysis, EarlyView.
Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani, Kirsten L. Rock, Kathleen Rice‐Davies, Rebecca Lo, Benedict Morley, Stephen Morley, Caroline S. Copeland   +6 more
wiley   +1 more source

The Role of Nitrous Oxide (“Laughing Gas”) in DUID Cases and Its Impact on Driving Fitness

Drug Testing and Analysis, EarlyView.
A total number of 39 cases of driving under the influence of nitrous oxide were investigated. Plasma concentrations of 0.22 to 17 mL/L (median:3.7 mL/L) were measured in blood samples withdrawn 38 to 144 min (median: 85 min) after control via Headspace‐GC–MS.
L. Lucuta, P. Stach, J. Hose, H. Andresen‐Streichert, M. Juebner   +4 more
wiley   +1 more source

Cannabis and the Cornea

Ocular Immunology and Inflammation, 2020
Purpose: While cannabis has the potential to reduce corneal pain, cannabinoids might induce side effects. This review article examines the effects of cannabinoids on the cornea. As more states and countries consider the legalization of adult cannabis use, health-care providers will need to identify ocular effects of cannabis consumption.Methods ...
Anne X. Nguyen, Albert Y. Wu
openaire   +3 more sources

UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Complex Regional Pain Syndrome

Brain and Behavior
Background Complex regional pain syndrome is characterized by severe, persistent pain. Emerging evidence suggests that cannabis‐based medicinal products may represent a new therapeutic option.
Lilia Evans, Simon Erridge, Madhur Varadpande, Arushika Aggarwal, Isaac Cowley, Evonne Clarke, Katy McLachlan, Ross Coomber, James J. Rucker, Michael Platt, Mikael H. Sodergren   +10 more
doaj   +1 more source

Hermaphroditism in Cannabis sativa L.: Impacts, Inducers, and Industry Implications

Plants
Cannabis sativa L. is a predominantly dioecious species, but sex expression is highly plastic and can be modified by genetic, hormonal, developmental, and environmental factors.
Chaylen Douglas Richards, Byeong-Ryeol Ryu, Gyeong-Ju Gim, Sang-Hyuck Park   +3 more
doaj   +1 more source

Mental Health and Well‐Being Across the Eating Disorder Spectrum—From Milder Symptoms of Disordered Eating Behaviors to Diagnosed Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examined differences in mental health and well‐being, risk behaviors, suicidality, and social functioning across a proposed eating disorder (ED) spectrum, ranging from no ED symptoms to clinically diagnosed EDs. Methods We examined 44,303 participants in the 18‐year follow‐up in the Danish National Birth Cohort (DNBC‐18 ...
Anne V. Aurup, Andrea Joensen, Else Marie Olsen, Nadia M. Mikkelsen, Stine Danielsen, Pernille Stemann Larsen, Katrine Strandberg‐Larsen   +6 more
wiley   +1 more source

Cannabidiol’s cytotoxicity in pancreatic cancer is induced via an upregulation of ceramide synthase 1 and ER stress

Journal of Cannabis Research
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies with a median 5 year-survival rate of 12%. Cannabidiol (CBD) has been found to exhibit antineoplastic potential and may potentiate the anticancer effects of cytotoxic’
Nagina Mangal, Vikash Reebye, Nagy Habib, Mikael H. Sodergren   +3 more
doaj   +1 more source