Results 51 to 60 of about 78,274 (168)

Cannabidiol’s cytotoxicity in pancreatic cancer is induced via an upregulation of ceramide synthase 1 and ER stress

Journal of Cannabis Research
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies with a median 5 year-survival rate of 12%. Cannabidiol (CBD) has been found to exhibit antineoplastic potential and may potentiate the anticancer effects of cytotoxic’
Nagina Mangal, Vikash Reebye, Nagy Habib, Mikael H. Sodergren   +3 more
doaj   +1 more source

The cannabis conundrum [PDF]

European Journal of Hospital Pharmacy, 2019
There is no doubt that the medicinal use of cannabis and cannabinoids is controversial. While there are few licensed products, there are plenty of chronic pain patients and parents of children with treatment resistant epilepsy who are convinced that cannabis derivatives help these conditions.
openaire   +2 more sources

High CBD extract (CBD-X) modulates inflammation and immune cell activity in rheumatoid arthritis

Frontiers in Immunology
IntroductionRheumatoid arthritis (RA) is a debilitating autoimmune disease affecting approximately 1% of the global population and is associated with significant morbidity and mortality.
Miran Aswad, Antonina Pechkovsky, Narmeen Ghanayiem, Haya Hamza, Igal Louria-Hayon, Igal Louria-Hayon   +5 more
doaj   +1 more source

High-CBD Extract (CBD-X) in Asthma Management: Reducing Th2-Driven Cytokine Secretion and Neutrophil/Eosinophil Activity

Pharmaceuticals
Background/Objectives: Asthma is a chronic inflammatory disorder of the airways affecting over 10% of the global population. It is characterized by airway inflammation, mucus hypersecretion, and bronchial hyperresponsiveness, driven predominantly by type
Miran Aswad, Antonina Pechkovsky, Narmeen Ghanayiem, Haya Hamza, Yaniv Dotan, Igal Louria-Hayon   +5 more
doaj   +1 more source

Cannabis [PDF]

Der Schmerz, 2019
Peter, Cremer-Schaeffer, Winfried, Häuser   +1 more
openaire   +2 more sources

Cannabigerol (CBG) Modulates Neutrophil Activity and Ameliorates Rheumatoid Arthritis Pathogenesis

Pharmaceuticals
Background/Objectives: Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease that primarily affects the joints. Current treatments aim to relieve pain and limit joint damage; however, many are associated with significant side effects ...
Miran Aswad, Antonina Pechkovsky, Haya Hamza, Igal Louria-Hayon   +3 more
doaj   +1 more source

Development and validation of a minimal SNP genotyping panel for the differentiation of Cannabis sativa cultivars

BMC Genomics
Background Due to its previously illicit nature, Cannabis sativa had not fully reaped the benefits of recent innovations in genomics and plant sciences. However, Canada’s legalization of C.
Alex Cull, David L. Joly
doaj   +1 more source

Hemp Extract (Extractum Cannabis) in the Treatment of Gastrointestinal Distress and Dyspepsia: Historical Insights from Barcelona, Spain

Pharmaceuticals
This study explores the trajectory of interest in and use of Extractum Cannabis (hemp extract, i.e., extract of Cannabis sativa L.) for the symptomatic treatment of minor gastrointestinal distress and dyspepsia in nineteenth- and early twentieth-century ...
Kenzi Riboulet-Zemouli, Josep Allué Creus   +1 more
doaj   +1 more source

Effects and safety of a CBD-rich Cannabis sativa oil in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial – CANOA – cannabis for osteoarthritis

Frontiers in Pharmacology
Osteoarthritis is a common inflammatory and degenerative joint disease characterized by associated chronic pain, often ensuing to diminished quality of life.
Andrés Mojoli, Osvaldo Haider, Yasmin Fakih, Maria Victoria Luz Gonçalves, Bruno Zepeda Rojas, Giovanna Xaia, Emanuelly Krefta, Maíra Assunção Bicca, Thiago Lopes de Mari, Charles Francisco Ferreira, Fernando Cezar-Dos-Santos, Aline Theodoro Toci, Francisney Pinto Nascimento   +12 more
doaj   +1 more source

Cannabis-based extract for managing pain in dogs with osteoarthritis: efficacy and safety assessment

Frontiers in Pharmacology
IntroductionCanine osteoarthritis (OA) is a prevalent disease characterized by progressive joint degeneration, pain, and impaired mobility. In older dogs, OA affects approximately 80% of the population.
Neide Maria Griebeler, Ricardo Penayo Cremonese, Yasmin Rafaela Fakih Correa, Priscila Romero Mazzini Pereira, Amanda Furjan Rial, Emanuela Leite, Maria Victoria Luz Gonçalves, Luiz Renato Marques das Almas, Nedice Borges Cardoso, Fernando Cezar-dos-Santos, Aline Theodoro Toci, Andrés Mojoli Le-Quesne, Francisney Pinto Nascimento   +12 more
doaj   +1 more source