Results 21 to 30 of about 1,532,463 (338)

Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials

Nature Medicine, 2023
The signaling-specific inhibitor AEF0117 selectively inhibits CB_1 activation by THC and reduces self-administration and subjective effects of cannabis in clinical trials, making it a potential treatment for cannabis use disorder.
M. Haney, M. Vallée, Sandy Fabre, Stephanie Collins Reed, Marion Zanese, Ghislaine Campistron, Caroline A. Arout, R. Foltin, Z. Cooper, T. Kearney-Ramos, Mathilde Metna, Zuzana Justinova, C. Schindler, Etienne Hebert-Chatelain, L. Bellocchio, A. Cathala, A. Bari, R. Serrat, David B. Finlay, F. Caraci, B. Redon, E. Martín-García, A. Busquets-García, Isabelle Matías, F. Levin, F. Felpin, Nicolas Simon, Daniela Cota, U. Spampinato, R. Maldonado, Y. Shaham, M. Glass, L. Thomsen, H. Mengel, G. Marsicano, S. Monlezun, J. Revest, Pier Vincenzo Piazza   +37 more
semanticscholar   +1 more source

Impact of cannabis consumption on the course of bipolar disorder

European Psychiatry, 2021
Introduction Although one third of patients with Bipolar Disorder have an addiction to Cannabis or an abused consumption, the interaction between cannabis use and bipolar disorder remains controversial.
S. Brahim, M.H. Aoun, R. Boukhchina, S. Ben Frej, M. Henia, L. Zarrouk   +5 more
doaj   +1 more source

Pain, Cannabis Species, and Cannabis Use Disorders [PDF]

Journal of Studies on Alcohol and Drugs, 2016
The purpose of this study was to examine whether individuals who used medical cannabis for chronic pain were at increased risk for cannabis use problems compared with individuals who used medical cannabis for other reasons (e.g., anxiety, insomnia, and muscle spasms).
Nicole L, Cohen, Adrienne J, Heinz, Mark, Ilgen, Marcel O, Bonn-Miller   +3 more
openaire   +2 more sources

State Cannabis Legalization and Cannabis Use Disorder in the US Veterans Health Administration, 2005 to 2019

JAMA psychiatry, 2023
This observational study assesses the role of medical cannabis law and recreational cannabis law enactment in diagnosed cannabis use disorder prevalence among Veterans Health Administration patients by using yearly electronic medical record data from ...
D. Hasin, M. Wall, C. J. Choi, Daniel M. Alschuler, C. Malte, M. Olfson, K. Keyes, J. Gradus, M. Cerdá, Charles C. Maynard, S. Keyhani, S. Martins, David S. Fink, O. Livne, Z. Mannes, S. Sherman, A. Saxon   +16 more
semanticscholar   +1 more source

Cannabis use and the risk of primary open-angle glaucoma: a Mendelian randomization study

Scientific Reports, 2023
Several observational studies have investigated the association between cannabis use and intraocular pressure, but its association with primary open-angle glaucoma (POAG) remains unclear.
Andreas Katsimpris, Sebastian-Edgar Baumeister, Hansjörg Baurecht, Andrew J. Tatham, Michael Nolde   +4 more
doaj   +1 more source

Cannabis use, cannabis use disorder and mental health disorders among pregnant and postpartum women in the US: A nationally representative study.

Drug and Alcohol Dependence, 2023
BACKGROUND Cannabis use and cannabis use disorder (CUD) are associated with mental health disorders, however the extent of this matter among pregnant and recently postpartum (e.g., new moms) women in the US is unknown.
Q. Brown, D. Shmulewitz, Aaron L Sarvet, K. Young-Wolff, Tyriesa Howard, D. Hasin   +5 more
semanticscholar   +1 more source

Cannabis use and its relationship with bipolar disorder: A systematic review and meta-analysis

Industrial Psychiatry Journal, 2023
Cannabis use has been stated as a causal risk factor for the occurrence of schizophrenia and other psychotic disorders. There is a dearth of literature stating the association of cannabis with bipolar disorder.
Gaurav Maggu, Swati Choudhary, Rajon Jaishy, Suprakash Chaudhury, Daniel Saldanha, Manish Borasi   +5 more
doaj   +1 more source

Cannabis use disorder and the future risk of cardiovascular disease in parous women: a longitudinal cohort study

BMC Medicine, 2020
Background Cannabis use is increasing in women of reproductive age, but whether cannabis use disorders increase the long-term risk of cardiovascular disease in this population is not known.
Nathalie Auger, Gilles Paradis, Nancy Low, Aimina Ayoub, Siyi He, Brian J. Potter   +5 more
doaj   +1 more source

Genetic basis of cannabis use: a systematic review

BMC Medical Genomics, 2021
Background With the increase in cannabis use rates, cannabis use disorder is being reported as one of the most common drug use disorders globally.
Alannah Hillmer, Caroul Chawar, Stephanie Sanger, Alessia D’Elia, Mehreen Butt, Raveena Kapoor, Flavio Kapczinski, Lehana Thabane, Zainab Samaan   +8 more
doaj   +1 more source

The association between cannabis use and outcome in pharmacological treatment for opioid use disorder

Harm Reduction Journal, 2021
Background With the ongoing opioid crisis and policy changes regarding legalization of cannabis occurring around the world, it is necessary to consider cannabis use in the context of opioid use disorder (OUD) and its treatment.
Tea Rosic, R. Kapoor, B. Panesar, Leen Naji, Darren B. Chai, N. Sanger, D. Marsh, A. Worster, L. Thabane, Z. Samaan   +9 more
semanticscholar   +1 more source