Results 41 to 50 of about 38,364 (253)

Medicinal Use of Cannabis in Children and Pregnant Women

Rambam Maimonides Medical Journal, 2020
The increasing medicinal use of cannabis during recent years has largely overlooked children and pregnant women due to litigious and ethical concerns.
Rana Cohen
doaj   +1 more source

Cannabis use among Norwegian university students: Gender differences, legalization support and use intentions, risk perceptions, and use disorder

Addictive Behaviors Reports, 2021
Aims: We explored past-year cannabis use and associated characteristics, focusing on legalization attitudes, use intentions, risk perceptions, and possible dependence among Norwegian university/college students.
Jasmina Burdzovic Andreas, Børge Sivertsen, Kari Jussie Lønning, Jens Christoffer Skogen   +3 more
doaj   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai, Anton L V Avanceña, Juan P Cata, Jamie C. Barner, Sharon H. Giordano, Chanhyun Park, Hui Zhao, Kirk E. Evoy, John K. Lin, Jennifer C. Spencer, Mariana Chavez‐MacGregor, Kelly K. Hunt, Kerollos Nashat Wanis   +12 more
wiley   +1 more source

Hours Since Last Drink Is Associated With Multiple Urine Ethyl Glucuronide Cutoffs Among Individuals With Alcohol Use Disorder

Drug Testing and Analysis, EarlyView.
Higher uEtG results indicated more recent drinking, rather than higher levels of alcohol consumption, and the period of detection of uEtG was shorter than previously reported. Even at low cutoffs, uEtG was best conceptualized as a measure of alcohol consumption in the prior 24 h.
Julianne D. Jett, Mohammad Keshtkar, Emma Seidler, Katharine Palmer, Diana Tyutyunnyk, Rachael Beck, Sara C. Parent, Douglas L. Weeks, Naomi Chaytor, Sterling M. McPherson, Michael G. McDonell   +10 more
wiley   +1 more source

The Neurobiology of Cannabis Use Disorders: A Call for Evidence [PDF]

Frontiers in Behavioral Neuroscience, 2016
Using cannabis is perceived by many as relatively harmless, but the adverse effects of problematic cannabis use are significant. Thirteen million individuals globally have Cannabis Use Disorders (CUDs; UNODC, 2015), with relapse rates comparable to those of other substance use disorders (~52–70%; Budney et al., 1999; Chauchard et al., 2013 ...
Lorenzetti, V, Cousijn, J, Solowij, N, Garavan, H, Suo, C, Yücel, M, Verdejo-García, A   +6 more
openaire   +7 more sources

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source

Factors associated with lower-risk cannabis use in adults in their mid-thirties

Journal of Cannabis Research
Background Harm reduction strategies encourage people who use cannabis to adopt lower-risk behaviors, such as refraining from daily or intensive use or limiting simultaneous use with other psychoactive substances.
Guillaume Dubé, Jennifer O’Loughlin, Jean-Sébastien Fallu, Christophe Huỳnh, Marie-Pierre Sylvestre   +4 more
doaj   +1 more source

Longitudinal Alterations in Prefrontal Resting Brain Connectivity in Non-Treatment-Seeking Young Adults With Cannabis Use Disorder

Frontiers in Psychiatry, 2019
Background: Cannabis is increasingly perceived as a harmless drug by recreational users, yet chronic use may impact brain changes into adulthood. Repeated cannabis exposure has been associated with enduring synaptic changes in executive control and ...
Jazmin Camchong, Paul F. Collins, Mary P. Becker, Kelvin O. Lim, Monica Luciana   +4 more
doaj   +1 more source

Adolescent cannabis use and the later onset of bipolar disorder: protocol for a systematic review and meta‐analysis of prospective cohort studies

Neuropsychopharmacology Reports, 2022
Background Cannabis is used by adolescents worldwide. Adolescents are more susceptible to the psychological effects of cannabis because their brains are still developing.
Naonori Yasuma, Kotaro Imamura, Kazuhiro Watanabe, Mako Iida, Ayumi Takano   +4 more
doaj   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source