Results 51 to 60 of about 38,260 (253)

The Use of Cannabis as a Predictor of Early Onset of Bipolar Disorder and Suicide Attempts

Neural Plasticity, 2015
Introduction. Bipolar disorder (BD) implies risk of suicide. The age at onset (AAO) of BD carries prognostic significance. Substance abuse may precede the onset of BD and cannabis is the most common illicit drug used.
Rafaela Torres Portugal Leite, Sarah de Oliveira Nogueira, João Paulo Rodrigues do Nascimento, Laisa Soares de Lima, Taís Bastos da Nóbrega, Mariana da Silva Virgínio, Lucas Monte da Costa Moreno, Bruno Henrique Barbosa Sampaio, Fábio Gomes de Matos e Souza   +8 more
doaj   +1 more source

Case Report: CBD Cigarettes for Harm Reduction and Adjunctive Therapy in a Patient With Schizophrenia and Substance Use Disorder

Frontiers in Psychiatry, 2021
The treatment of patients with schizophrenia and substance use disorder poses a challenge for clinicians. Continued use of cannabis and cocaine can exacerbate psychotic symptoms and worsen the course of disease.
Maximilian Meyer, Marc Walter, Stefan Borgwardt, Alexandra Scheidegger, Elisabeth Lang, Patrick Köck   +5 more
doaj   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Adverse Cardiovascular Outcomes in Young Cannabis Users: A Nationwide Analysis

Hearts
Background: With the growing trends in recreational marijuana use, our study aims at analyzing the association between acute coronary syndromes (ACS) and ventricular fibrillation (Vfib) and cannabis use disorder in young adults (18–45).
Vivek Joseph Varughese, Yoshua Mathai, Cara Joseph, Logan Carlyle   +3 more
doaj   +1 more source

Adverse Childhood Experiences and Substance Use: The Mediating Role of Executive Function Deficits

Journal of Adolescence, EarlyView.
ABSTRACT Introduction While adverse childhood experiences (ACEs) are robust risk factors for adolescent substance use, the prospective neurocognitive pathways linking both cumulative and specific adversities to substance use remain understudied. This study tested a vulnerability model by examining whether executive function (EF) deficits mediate the ...
Mahsa P. Yousefkhani, Xiafei Wang, Sara A. Vasilenko   +2 more
wiley   +1 more source

A national population-based study of cannabis use and correlates among U.S. veterans prescribed opioids in primary care

BMC Psychiatry, 2023
Background Cannabis is marketed as a treatment for pain. There is limited data on the prevalence of cannabis use and its correlates among Veterans prescribed opioids.
Tauheed Zaman, Dawn M. Bravata, Amy L. Byers, Erin E. Krebs, Samuel J. Leonard, Friedhelm Sandbrink, Wylie Barker, Salomeh Keyhani   +7 more
doaj   +1 more source

Decision‐making and risk‐taking as predictors of health risk behaviors in the Millennium Cohort Study

JCPP Advances, EarlyView.
Abstract Background Facets of decision‐making and risk‐taking are implicated in adolescent health risk behaviors; however, whether they may lead to adolescent engagement in substance use, gambling, and self‐harm is unknown. Methods We used the Millennium Cohort Study to test whether a task‐based measure of decision‐making and risk‐taking predicts ...
Nicole G. Hammond, Georgia Condran, Elise E. DeVito, Marie‐Claude Geoffroy, Ian Colman   +4 more
wiley   +1 more source

Evaluation and treatment of mental health symptoms among unaccompanied migrant children and adolescents in the United States: A systematic review

JCPP Advances, EarlyView.
Abstract Background Unaccompanied migrant youths are at elevated risk for exposure to trauma and related mental health challenges, but there is minimal evidence guiding best practices. We conducted a systematic review of quantitative studies that examined mental health evaluation and treatment services for unaccompanied migrant youths resettled in the ...
Natan J. Vega Potler, Sebastian Villegas, Dorice Vieira, Sarah M. Horwitz   +3 more
wiley   +1 more source

Sequelae of child maltreatment: Umbrella synthesis of 148 meta‐analyses on the mental health correlates

JCPP Advances, EarlyView.
Our umbrella synthesis found strong, often equivalent, associations between child maltreatment and all examined mental health difficulties. Different types of maltreatment appear to have comparably negative effects on mental health. If replicated, these findings may cause us to reconsider conventional wisdom that suggests some forms of CM are less ...
Barry Coughlan, Robbie Duschinsky, Marian J. Bakermans‐Kranenburg, Lianne Bakkum, Guy C. M. Skinner, Alfred Markham, Helen Beckwith, Marinus H. van Ijzendoorn   +7 more
wiley   +1 more source